Matches in SemOpenAlex for { <https://semopenalex.org/work/W3201239614> ?p ?o ?g. }
Showing items 1 to 99 of
99
with 100 items per page.
- W3201239614 endingPage "179" @default.
- W3201239614 startingPage "171" @default.
- W3201239614 abstract "Monoclonal immunoglobulins (M-proteins) that migrate in the β region on serum protein electrophoresis (SPEP) are often cloaked by this region's normal constituents. The present study interrogates the utility of using both quantitative and qualitative alterations in β-region bands for detection of β-migrating M-proteins.Consecutive SPEP cases analyzed by capillary electrophoresis were searched to identify the initial workup on 1,841 patients with increased total β regions, suspicious β-region findings resulting in reflex immunofixation (IFE), or immunosubtraction (ISUB). To augment quantitative information, separate β1 and β2 measurements were established and retrospectively used to evaluate their sensitivity for M-protein detection.We identified M-proteins in 205 (11.1%) cases, including immunoglobulin A (IgA) (54%), IgG (24%), IgM (13%), and free light chain (9%) isotypes. Of the 15 cases flagged by separate β1 and β2 measurements that were not identified by total β-region measurement, 1 progressed to myeloma. Of the 56 β-migrating M-proteins identified by qualitative features but without increase in any of the β-region measurements, 1 progressed to myeloma.A combination of separate measurements for β1 and β2 regions together with detection of β-region distortions increase sensitivity for identifying β-migrating M-proteins via reflex IFE or ISUB." @default.
- W3201239614 created "2021-09-27" @default.
- W3201239614 creator A5016256229 @default.
- W3201239614 creator A5043828812 @default.
- W3201239614 creator A5068292077 @default.
- W3201239614 creator A5084690409 @default.
- W3201239614 date "2021-09-14" @default.
- W3201239614 modified "2023-10-01" @default.
- W3201239614 title "Reflexing Suspicious β-Region Findings on Capillary Serum Protein Electrophoresis to Immunofixation or Immunosubtraction for Detecting Monoclonal Proteins" @default.
- W3201239614 cites W1983664239 @default.
- W3201239614 cites W2023924548 @default.
- W3201239614 cites W2027027958 @default.
- W3201239614 cites W2031157863 @default.
- W3201239614 cites W2047688374 @default.
- W3201239614 cites W2089827806 @default.
- W3201239614 cites W2124240218 @default.
- W3201239614 cites W2143134528 @default.
- W3201239614 cites W2144728882 @default.
- W3201239614 cites W2144930991 @default.
- W3201239614 cites W2165974443 @default.
- W3201239614 cites W2211044314 @default.
- W3201239614 cites W2296238406 @default.
- W3201239614 cites W2567669025 @default.
- W3201239614 cites W2610715546 @default.
- W3201239614 cites W2785817645 @default.
- W3201239614 cites W2793091745 @default.
- W3201239614 cites W3093376706 @default.
- W3201239614 cites W4238153906 @default.
- W3201239614 cites W3143387670 @default.
- W3201239614 doi "https://doi.org/10.1093/ajcp/aqab108" @default.
- W3201239614 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/34519791" @default.
- W3201239614 hasPublicationYear "2021" @default.
- W3201239614 type Work @default.
- W3201239614 sameAs 3201239614 @default.
- W3201239614 citedByCount "2" @default.
- W3201239614 countsByYear W32012396142023 @default.
- W3201239614 crossrefType "journal-article" @default.
- W3201239614 hasAuthorship W3201239614A5016256229 @default.
- W3201239614 hasAuthorship W3201239614A5043828812 @default.
- W3201239614 hasAuthorship W3201239614A5068292077 @default.
- W3201239614 hasAuthorship W3201239614A5084690409 @default.
- W3201239614 hasConcept C101660505 @default.
- W3201239614 hasConcept C142724271 @default.
- W3201239614 hasConcept C153911025 @default.
- W3201239614 hasConcept C159654299 @default.
- W3201239614 hasConcept C163864487 @default.
- W3201239614 hasConcept C181199279 @default.
- W3201239614 hasConcept C188758523 @default.
- W3201239614 hasConcept C203014093 @default.
- W3201239614 hasConcept C2776364478 @default.
- W3201239614 hasConcept C2776855637 @default.
- W3201239614 hasConcept C2778808339 @default.
- W3201239614 hasConcept C2900643 @default.
- W3201239614 hasConcept C35859425 @default.
- W3201239614 hasConcept C36394416 @default.
- W3201239614 hasConcept C542903549 @default.
- W3201239614 hasConcept C55493867 @default.
- W3201239614 hasConcept C71924100 @default.
- W3201239614 hasConcept C86803240 @default.
- W3201239614 hasConceptScore W3201239614C101660505 @default.
- W3201239614 hasConceptScore W3201239614C142724271 @default.
- W3201239614 hasConceptScore W3201239614C153911025 @default.
- W3201239614 hasConceptScore W3201239614C159654299 @default.
- W3201239614 hasConceptScore W3201239614C163864487 @default.
- W3201239614 hasConceptScore W3201239614C181199279 @default.
- W3201239614 hasConceptScore W3201239614C188758523 @default.
- W3201239614 hasConceptScore W3201239614C203014093 @default.
- W3201239614 hasConceptScore W3201239614C2776364478 @default.
- W3201239614 hasConceptScore W3201239614C2776855637 @default.
- W3201239614 hasConceptScore W3201239614C2778808339 @default.
- W3201239614 hasConceptScore W3201239614C2900643 @default.
- W3201239614 hasConceptScore W3201239614C35859425 @default.
- W3201239614 hasConceptScore W3201239614C36394416 @default.
- W3201239614 hasConceptScore W3201239614C542903549 @default.
- W3201239614 hasConceptScore W3201239614C55493867 @default.
- W3201239614 hasConceptScore W3201239614C71924100 @default.
- W3201239614 hasConceptScore W3201239614C86803240 @default.
- W3201239614 hasIssue "2" @default.
- W3201239614 hasLocation W32012396141 @default.
- W3201239614 hasLocation W32012396142 @default.
- W3201239614 hasOpenAccess W3201239614 @default.
- W3201239614 hasPrimaryLocation W32012396141 @default.
- W3201239614 hasRelatedWork W119914118 @default.
- W3201239614 hasRelatedWork W1988327297 @default.
- W3201239614 hasRelatedWork W2060630093 @default.
- W3201239614 hasRelatedWork W2359520097 @default.
- W3201239614 hasRelatedWork W2389653796 @default.
- W3201239614 hasRelatedWork W2610715546 @default.
- W3201239614 hasRelatedWork W2967491443 @default.
- W3201239614 hasRelatedWork W3031315740 @default.
- W3201239614 hasRelatedWork W3135402041 @default.
- W3201239614 hasRelatedWork W4281651215 @default.
- W3201239614 hasVolume "157" @default.
- W3201239614 isParatext "false" @default.
- W3201239614 isRetracted "false" @default.
- W3201239614 magId "3201239614" @default.
- W3201239614 workType "article" @default.