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- W3201280954 abstract "BACKGROUND Breast cancer is an uncommon (rare) disease in men, approximately 1% of the total breast cancer cases in the world. By reason of the rare occurrence, there is no clinical or hospital study giving the information about the essential trace and toxic elements in the biological samples of male breast cancer patients. METHODS The aim of current study was to estimate association among essential trace {zinc (Zn), iron (Fe) and copper (Cu)} and toxic {cadmium (Cd) and lead (Pb)} elements in human biological samples particularly blood, serum, scalp hair, of male breast cancer patients (n = 14, age range 52 - 58 years) residents of Hyderabad, Pakistan. For comparative purposes, the biological samples of referent persons (n = 37) of the same age groups were also be analyzed. Microwave oven mediated digestion method was employed, and digestion of samples was carried out with the help of 2:1 mixture solution of HNO3 (65%) and H2O2 (30%). Atomic absorption spectrometry was employed for the determination of elemental concentrations from the microwave oven employed digested samples. RESULTS The found average of essential elements (zinc, iron, and copper) in samples of male breast cancer patients was found to be lower, while cadmium and nickel were found to be higher, when compared with samples from referents (p < 0.001). CONCLUSIONS These data will be helpful for treatment of male breast cancer patients to improve his health and life." @default.
- W3201280954 created "2021-09-27" @default.
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- W3201280954 date "2021-01-01" @default.
- W3201280954 modified "2023-09-26" @default.
- W3201280954 title "Elemental Concentration in the Biological Samples of Pakistani Male Breast Cancer Patients" @default.
- W3201280954 doi "https://doi.org/10.7754/clin.lab.2021.201223" @default.
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