Matches in SemOpenAlex for { <https://semopenalex.org/work/W3201291206> ?p ?o ?g. }
Showing items 1 to 86 of
86
with 100 items per page.
- W3201291206 endingPage "1653" @default.
- W3201291206 startingPage "1647" @default.
- W3201291206 abstract "MicroRNA (miRNA) has emerged as an important gene-regulator that shows great potential in gene therapy because of its unique roles in gene-regulation. However, the knowledge on their function and transportation in vivo is still lacking, and there are limited obvious evidences to define intracellular transportation of miRNA. In this study, the dynamics of exogenous miR-21 transfected into HeLa cells was traced by live-cell microscopy. Their transportation at key time points was recorded and dynamic properties were analyzed by single particle tracking (SPT) and mean square displacement (MSD) calculation. Results showed that the exogenous miRNAs bounded to cells quickly and went through lysosome into cytosol, where they were subsequently recruited into p-body. They finally were degraded, otherwise went back to cytosol in some way. Long time observation and analysis of motion mode showed that the miRNAs were confined in a small region and their motion modes were flexible in different intracellular microenvironment after entering the cells." @default.
- W3201291206 created "2021-09-27" @default.
- W3201291206 creator A5001962625 @default.
- W3201291206 creator A5047316470 @default.
- W3201291206 creator A5063627915 @default.
- W3201291206 creator A5065418938 @default.
- W3201291206 creator A5068697434 @default.
- W3201291206 creator A5083427382 @default.
- W3201291206 date "2021-08-01" @default.
- W3201291206 modified "2023-09-30" @default.
- W3201291206 title "Dynamics and Traffic for Transfecting Exogenous MicroRNA as Studied by Live-Cell Microscopy" @default.
- W3201291206 doi "https://doi.org/10.1166/jbn.2021.3129" @default.
- W3201291206 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/34544541" @default.
- W3201291206 hasPublicationYear "2021" @default.
- W3201291206 type Work @default.
- W3201291206 sameAs 3201291206 @default.
- W3201291206 citedByCount "1" @default.
- W3201291206 countsByYear W32012912062023 @default.
- W3201291206 crossrefType "journal-article" @default.
- W3201291206 hasAuthorship W3201291206A5001962625 @default.
- W3201291206 hasAuthorship W3201291206A5047316470 @default.
- W3201291206 hasAuthorship W3201291206A5063627915 @default.
- W3201291206 hasAuthorship W3201291206A5065418938 @default.
- W3201291206 hasAuthorship W3201291206A5068697434 @default.
- W3201291206 hasAuthorship W3201291206A5083427382 @default.
- W3201291206 hasConcept C104317684 @default.
- W3201291206 hasConcept C111368507 @default.
- W3201291206 hasConcept C121332964 @default.
- W3201291206 hasConcept C127313418 @default.
- W3201291206 hasConcept C145059251 @default.
- W3201291206 hasConcept C145912823 @default.
- W3201291206 hasConcept C1491633281 @default.
- W3201291206 hasConcept C15526883 @default.
- W3201291206 hasConcept C181199279 @default.
- W3201291206 hasConcept C185592680 @default.
- W3201291206 hasConcept C203635412 @default.
- W3201291206 hasConcept C24890656 @default.
- W3201291206 hasConcept C2777366897 @default.
- W3201291206 hasConcept C54009773 @default.
- W3201291206 hasConcept C54355233 @default.
- W3201291206 hasConcept C55493867 @default.
- W3201291206 hasConcept C79879829 @default.
- W3201291206 hasConcept C86803240 @default.
- W3201291206 hasConcept C95444343 @default.
- W3201291206 hasConcept C98539663 @default.
- W3201291206 hasConceptScore W3201291206C104317684 @default.
- W3201291206 hasConceptScore W3201291206C111368507 @default.
- W3201291206 hasConceptScore W3201291206C121332964 @default.
- W3201291206 hasConceptScore W3201291206C127313418 @default.
- W3201291206 hasConceptScore W3201291206C145059251 @default.
- W3201291206 hasConceptScore W3201291206C145912823 @default.
- W3201291206 hasConceptScore W3201291206C1491633281 @default.
- W3201291206 hasConceptScore W3201291206C15526883 @default.
- W3201291206 hasConceptScore W3201291206C181199279 @default.
- W3201291206 hasConceptScore W3201291206C185592680 @default.
- W3201291206 hasConceptScore W3201291206C203635412 @default.
- W3201291206 hasConceptScore W3201291206C24890656 @default.
- W3201291206 hasConceptScore W3201291206C2777366897 @default.
- W3201291206 hasConceptScore W3201291206C54009773 @default.
- W3201291206 hasConceptScore W3201291206C54355233 @default.
- W3201291206 hasConceptScore W3201291206C55493867 @default.
- W3201291206 hasConceptScore W3201291206C79879829 @default.
- W3201291206 hasConceptScore W3201291206C86803240 @default.
- W3201291206 hasConceptScore W3201291206C95444343 @default.
- W3201291206 hasConceptScore W3201291206C98539663 @default.
- W3201291206 hasIssue "8" @default.
- W3201291206 hasLocation W32012912061 @default.
- W3201291206 hasOpenAccess W3201291206 @default.
- W3201291206 hasPrimaryLocation W32012912061 @default.
- W3201291206 hasRelatedWork W149502054 @default.
- W3201291206 hasRelatedWork W2004487226 @default.
- W3201291206 hasRelatedWork W2006693860 @default.
- W3201291206 hasRelatedWork W2015051372 @default.
- W3201291206 hasRelatedWork W2071063451 @default.
- W3201291206 hasRelatedWork W2365174857 @default.
- W3201291206 hasRelatedWork W2369148478 @default.
- W3201291206 hasRelatedWork W4220781642 @default.
- W3201291206 hasRelatedWork W4318161862 @default.
- W3201291206 hasRelatedWork W4365443771 @default.
- W3201291206 hasVolume "17" @default.
- W3201291206 isParatext "false" @default.
- W3201291206 isRetracted "false" @default.
- W3201291206 magId "3201291206" @default.
- W3201291206 workType "article" @default.