FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W3201319100> ?p ?o ?g. }

• W3201319100 endingPage "100120" @default.
• W3201319100 startingPage "100120" @default.
• W3201319100 abstract "Diabetic nephropathy is a major complication of diabetes mellitus, and thus novel biomarkers are desired to evaluate the presence and progression of diabetic nephropathy. In this study, we sought to identify possible metabolites related to diabetic nephropathy among urinary eicosanoids and related mediators. Using liquid chromatogram-tandem mass spectrometry, we optimized the lipid extraction from urine using the Monospin C18 as a solid-phase extraction cartridge and measured the urinary lipid mediators in 111 subjects with type 2 diabetes mellitus as well as 33 healthy subjects. We observed that 14 metabolites differed significantly among the clinical stages of nephropathy. Among them, levels of tetranor-prostaglandin E metabolite (tetranor-PGEM), an arachidonic acid metabolite, were significantly higher in subjects with stage 1 nephropathy than in healthy subjects and increased with the progression of nephropathy. We also observed that levels of maresin-1, a docosahexaenoic acid metabolite, and leukotriene B4-ethanolamide, an arachidonoyl ethanolamide metabolite, were significantly lower in subjects with stage 3-4 nephropathy than in healthy subjects and those with stage 1-2 nephropathy. Finally, using a comprehensive analysis of urinary eicosanoids and related mediators, we concluded that tetranor-PGEM was capable of discriminating clinical stages of nephropathy and thus useful as a novel biomarker for diabetic nephropathy." @default.
• W3201319100 created "2021-09-27" @default.
• W3201319100 creator A5004173815 @default.
• W3201319100 creator A5026162371 @default.
• W3201319100 creator A5042125737 @default.
• W3201319100 creator A5059263459 @default.
• W3201319100 creator A5060462446 @default.
• W3201319100 creator A5077332068 @default.
• W3201319100 date "2021-01-01" @default.
• W3201319100 modified "2023-10-18" @default.
• W3201319100 title "Simultaneous analyses of urinary eicosanoids and related mediators identified tetranor-prostaglandin E metabolite as a novel biomarker of diabetic nephropathy" @default.
• W3201319100 cites W1970668209 @default.
• W3201319100 cites W1980344936 @default.
• W3201319100 cites W1983604563 @default.
• W3201319100 cites W2002455578 @default.
• W3201319100 cites W2004421629 @default.
• W3201319100 cites W2005581755 @default.
• W3201319100 cites W2032579917 @default.
• W3201319100 cites W2053230486 @default.
• W3201319100 cites W2058541568 @default.
• W3201319100 cites W2085673497 @default.
• W3201319100 cites W2087112943 @default.
• W3201319100 cites W2124622798 @default.
• W3201319100 cites W2136679436 @default.
• W3201319100 cites W2137412478 @default.
• W3201319100 cites W2148740884 @default.
• W3201319100 cites W2171565169 @default.
• W3201319100 cites W2293276114 @default.
• W3201319100 cites W2626362188 @default.
• W3201319100 cites W2790272775 @default.
• W3201319100 cites W2890994536 @default.
• W3201319100 cites W2951411706 @default.
• W3201319100 cites W2955830011 @default.
• W3201319100 cites W2968989375 @default.
• W3201319100 cites W2983001709 @default.
• W3201319100 cites W412403171 @default.
• W3201319100 cites W779449604 @default.
• W3201319100 doi "https://doi.org/10.1016/j.jlr.2021.100120" @default.
• W3201319100 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/8515300" @default.
• W3201319100 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/34560080" @default.
• W3201319100 hasPublicationYear "2021" @default.
• W3201319100 type Work @default.
• W3201319100 sameAs 3201319100 @default.
• W3201319100 citedByCount "11" @default.
• W3201319100 countsByYear W32013191002022 @default.
• W3201319100 countsByYear W32013191002023 @default.
• W3201319100 crossrefType "journal-article" @default.
• W3201319100 hasAuthorship W3201319100A5004173815 @default.
• W3201319100 hasAuthorship W3201319100A5026162371 @default.
• W3201319100 hasAuthorship W3201319100A5042125737 @default.
• W3201319100 hasAuthorship W3201319100A5059263459 @default.
• W3201319100 hasAuthorship W3201319100A5060462446 @default.
• W3201319100 hasAuthorship W3201319100A5077332068 @default.
• W3201319100 hasBestOaLocation W32013191001 @default.
• W3201319100 hasConcept C126322002 @default.
• W3201319100 hasConcept C134018914 @default.
• W3201319100 hasConcept C181199279 @default.
• W3201319100 hasConcept C185592680 @default.
• W3201319100 hasConcept C2776352991 @default.
• W3201319100 hasConcept C2777180221 @default.
• W3201319100 hasConcept C2777477808 @default.
• W3201319100 hasConcept C2778078955 @default.
• W3201319100 hasConcept C2779922275 @default.
• W3201319100 hasConcept C2780026642 @default.
• W3201319100 hasConcept C2781184683 @default.
• W3201319100 hasConcept C2781197716 @default.
• W3201319100 hasConcept C55493867 @default.
• W3201319100 hasConcept C555293320 @default.
• W3201319100 hasConcept C71924100 @default.
• W3201319100 hasConcept C77411442 @default.
• W3201319100 hasConceptScore W3201319100C126322002 @default.
• W3201319100 hasConceptScore W3201319100C134018914 @default.
• W3201319100 hasConceptScore W3201319100C181199279 @default.
• W3201319100 hasConceptScore W3201319100C185592680 @default.
• W3201319100 hasConceptScore W3201319100C2776352991 @default.
• W3201319100 hasConceptScore W3201319100C2777180221 @default.
• W3201319100 hasConceptScore W3201319100C2777477808 @default.
• W3201319100 hasConceptScore W3201319100C2778078955 @default.
• W3201319100 hasConceptScore W3201319100C2779922275 @default.
• W3201319100 hasConceptScore W3201319100C2780026642 @default.
• W3201319100 hasConceptScore W3201319100C2781184683 @default.
• W3201319100 hasConceptScore W3201319100C2781197716 @default.
• W3201319100 hasConceptScore W3201319100C55493867 @default.
• W3201319100 hasConceptScore W3201319100C555293320 @default.
• W3201319100 hasConceptScore W3201319100C71924100 @default.
• W3201319100 hasConceptScore W3201319100C77411442 @default.
• W3201319100 hasLocation W32013191001 @default.
• W3201319100 hasLocation W32013191002 @default.
• W3201319100 hasLocation W32013191003 @default.
• W3201319100 hasOpenAccess W3201319100 @default.
• W3201319100 hasPrimaryLocation W32013191001 @default.
• W3201319100 hasRelatedWork W2032111989 @default.
• W3201319100 hasRelatedWork W2032738451 @default.
• W3201319100 hasRelatedWork W2038657938 @default.
• W3201319100 hasRelatedWork W2047956456 @default.
• W3201319100 hasRelatedWork W2075939542 @default.
• W3201319100 hasRelatedWork W2104195310 @default.
• W3201319100 hasRelatedWork W2406277046 @default.

• next