Matches in SemOpenAlex for { <https://semopenalex.org/work/W3201415977> ?p ?o ?g. }
Showing items 1 to 94 of
94
with 100 items per page.
- W3201415977 endingPage "40" @default.
- W3201415977 startingPage "34" @default.
- W3201415977 abstract "Previous studies have shown that a patent, watertight esophageal anastomosis can be accomplished safely using specially-shaped magnets in piglets. However, it is unclear whether such a magnetic esophageal compression anastomosis (MECA) remains patent in the long-term. The purpose of this study was to evaluate the long-term outcome of MECA in an experimental pig model over an observation period of 2 months.Ten piglets underwent creation of an MECA with custom-made 8 mm magnets and a U-shaped esophageal bypass loop to allow peroral nutrition at eight weeks of life. Two weeks later, the bypass loop was closed surgically, requiring the pigs to swallow via the newly created magnetic compression anastomosis. The pigs were fed soft chow for 2 months. They were monitored for weight gain and signs of dysphagia. At the endpoint of two months, esophagoscopy and contrast esophagography was performed. After removal of the esophagus, the tissues were macroscopiocally and histologically assessed.Six piglets survived until the endpoint. In two pigs, closure of the bypass loop failed, these demonstrated mean weight gain of 792 gs/day [95% Confidence interval 575 to 1009 gs/day]. Weight gain in four pigs that exclusively fed via the magnetic anastomosis averaged 577 gs/day [95% confidence interval 434 to 719 gs/day (p = 0.18)]. There were no signs of dysphagia. All magnets passed with the stool within 16 days. After 2 months, a well-formed magnetic compression anastomosis was visible and easily negotiated with a 6.5 mm endoscope. Esophogram and macroscopic findings confirmed patentency of the esophageal anastomoses. Histopathology showed a circular anastomosis lined with contiguous epithelium.MECA creates a long-term functional and patent anastomosis in pigs. This concept may facilitate minimally-invasive esophageal atresia repair by obviating a technically challenging and time-consuming hand-sewn anastomosis." @default.
- W3201415977 created "2021-09-27" @default.
- W3201415977 creator A5016346717 @default.
- W3201415977 creator A5034413406 @default.
- W3201415977 creator A5038465174 @default.
- W3201415977 creator A5045592416 @default.
- W3201415977 creator A5049753468 @default.
- W3201415977 creator A5051192670 @default.
- W3201415977 creator A5057067159 @default.
- W3201415977 creator A5069645782 @default.
- W3201415977 creator A5084885911 @default.
- W3201415977 creator A5090698923 @default.
- W3201415977 date "2022-01-01" @default.
- W3201415977 modified "2023-10-01" @default.
- W3201415977 title "An experimental study on long term outcomes after magnetic esophageal compression anastomosis in piglets" @default.
- W3201415977 cites W2000170067 @default.
- W3201415977 cites W2018906274 @default.
- W3201415977 cites W2045955863 @default.
- W3201415977 cites W2066407068 @default.
- W3201415977 cites W2123973805 @default.
- W3201415977 cites W2279699835 @default.
- W3201415977 cites W2310903781 @default.
- W3201415977 cites W2720264530 @default.
- W3201415977 cites W2750545711 @default.
- W3201415977 cites W2751224308 @default.
- W3201415977 cites W2762126559 @default.
- W3201415977 cites W2891044887 @default.
- W3201415977 cites W2893109200 @default.
- W3201415977 cites W2944067808 @default.
- W3201415977 cites W2973600732 @default.
- W3201415977 cites W2986565699 @default.
- W3201415977 cites W3003305375 @default.
- W3201415977 cites W3003810066 @default.
- W3201415977 cites W3030225815 @default.
- W3201415977 cites W3097118569 @default.
- W3201415977 cites W3127405034 @default.
- W3201415977 doi "https://doi.org/10.1016/j.jpedsurg.2021.09.032" @default.
- W3201415977 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/34656308" @default.
- W3201415977 hasPublicationYear "2022" @default.
- W3201415977 type Work @default.
- W3201415977 sameAs 3201415977 @default.
- W3201415977 citedByCount "6" @default.
- W3201415977 countsByYear W32014159772022 @default.
- W3201415977 countsByYear W32014159772023 @default.
- W3201415977 crossrefType "journal-article" @default.
- W3201415977 hasAuthorship W3201415977A5016346717 @default.
- W3201415977 hasAuthorship W3201415977A5034413406 @default.
- W3201415977 hasAuthorship W3201415977A5038465174 @default.
- W3201415977 hasAuthorship W3201415977A5045592416 @default.
- W3201415977 hasAuthorship W3201415977A5049753468 @default.
- W3201415977 hasAuthorship W3201415977A5051192670 @default.
- W3201415977 hasAuthorship W3201415977A5057067159 @default.
- W3201415977 hasAuthorship W3201415977A5069645782 @default.
- W3201415977 hasAuthorship W3201415977A5084885911 @default.
- W3201415977 hasAuthorship W3201415977A5090698923 @default.
- W3201415977 hasConcept C126322002 @default.
- W3201415977 hasConcept C141071460 @default.
- W3201415977 hasConcept C2776820786 @default.
- W3201415977 hasConcept C2777819096 @default.
- W3201415977 hasConcept C2780596822 @default.
- W3201415977 hasConcept C44249647 @default.
- W3201415977 hasConcept C71924100 @default.
- W3201415977 hasConcept C8443397 @default.
- W3201415977 hasConceptScore W3201415977C126322002 @default.
- W3201415977 hasConceptScore W3201415977C141071460 @default.
- W3201415977 hasConceptScore W3201415977C2776820786 @default.
- W3201415977 hasConceptScore W3201415977C2777819096 @default.
- W3201415977 hasConceptScore W3201415977C2780596822 @default.
- W3201415977 hasConceptScore W3201415977C44249647 @default.
- W3201415977 hasConceptScore W3201415977C71924100 @default.
- W3201415977 hasConceptScore W3201415977C8443397 @default.
- W3201415977 hasFunder F4320306899 @default.
- W3201415977 hasIssue "1" @default.
- W3201415977 hasLocation W32014159771 @default.
- W3201415977 hasLocation W32014159772 @default.
- W3201415977 hasOpenAccess W3201415977 @default.
- W3201415977 hasPrimaryLocation W32014159771 @default.
- W3201415977 hasRelatedWork W1560045202 @default.
- W3201415977 hasRelatedWork W156330091 @default.
- W3201415977 hasRelatedWork W2014435840 @default.
- W3201415977 hasRelatedWork W2017705908 @default.
- W3201415977 hasRelatedWork W2101162798 @default.
- W3201415977 hasRelatedWork W2378358762 @default.
- W3201415977 hasRelatedWork W2397422327 @default.
- W3201415977 hasRelatedWork W3170439550 @default.
- W3201415977 hasRelatedWork W4319982561 @default.
- W3201415977 hasRelatedWork W93911891 @default.
- W3201415977 hasVolume "57" @default.
- W3201415977 isParatext "false" @default.
- W3201415977 isRetracted "false" @default.
- W3201415977 magId "3201415977" @default.
- W3201415977 workType "article" @default.