FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W3201452605> ?p ?o ?g. }

• W3201452605 endingPage "1206" @default.
• W3201452605 startingPage "1206" @default.
• W3201452605 abstract "With the stable gastric pentadecapeptide BPC 157 therapy known to heal various both external and internal rat fistulas, we attempt to approach vesicovaginal fistula, continuous urine leaking through vagina, bladder stones, and a possible therapy solution among rats with well-formed 2 week-fistulas (vaginal/vesical 4 mm large defects) started with delayed therapy. Subsequent control fistula course (the subsequent 1, 2, 4, and 6 weeks) since beginning revealed the failed healing, fistula leaking, adhesions, urinary leaking through vagina, failed epithelization, collagenization, granulation tissue and neovascularization, increased inflammation, and necrosis. Thereby, the later intervals revealed the persistent inability to sustain even minimal volume, vesical, and vaginal defects and stone formation at the end of the experiment (fistula-time day 56). BPC 157 therapy (10 µg/kg, 10 ng/kg, intraperitoneally once time daily or perorally in drinking water until sacrifice) was initiated with a considerable delay (at 2 weeks after fistula formation). Already within 1 week therapy, all BPC 157 regimens stopped urinary leaking through vagina, reversed the otherwise resistant poor healing course to the increased epithelization, collagenization, granulation tissue and neovascularization, decreased inflammation, and decreased necrosis. Thereby, at later intervals, all BPC 157 rats exhibited a five times larger volume that can be sustained before leaking as in healthy, vesical, and vaginal defects completely closed and no stone formation. Thus, macro/microscopic and functional recovery, and counteracted stone formation. Concluding, BPC 157 therapy’s beneficial effects resulted in healing and no stone formation, with µg- and ng-regimens, either given daily perorally in drinking water or intraperitoneally." @default.
• W3201452605 created "2021-09-27" @default.
• W3201452605 creator A5001768226 @default.
• W3201452605 creator A5006573657 @default.
• W3201452605 creator A5017004450 @default.
• W3201452605 creator A5017246332 @default.
• W3201452605 creator A5017342414 @default.
• W3201452605 creator A5035499944 @default.
• W3201452605 creator A5043779562 @default.
• W3201452605 creator A5050435159 @default.
• W3201452605 creator A5051423361 @default.
• W3201452605 creator A5059679692 @default.
• W3201452605 creator A5060443436 @default.
• W3201452605 creator A5075391124 @default.
• W3201452605 date "2021-09-13" @default.
• W3201452605 modified "2023-09-24" @default.
• W3201452605 title "Stable Gastric Pentadecapeptide BPC 157 Heals Established Vesicovaginal Fistula and Counteracts Stone Formation in Rats" @default.
• W3201452605 cites W1488353016 @default.
• W3201452605 cites W1923023830 @default.
• W3201452605 cites W1970728993 @default.
• W3201452605 cites W1973607009 @default.
• W3201452605 cites W1979034975 @default.
• W3201452605 cites W1985100420 @default.
• W3201452605 cites W1991392947 @default.
• W3201452605 cites W1992156646 @default.
• W3201452605 cites W2010381460 @default.
• W3201452605 cites W2011674093 @default.
• W3201452605 cites W2021530697 @default.
• W3201452605 cites W2025909685 @default.
• W3201452605 cites W2034300124 @default.
• W3201452605 cites W2039145880 @default.
• W3201452605 cites W2048474932 @default.
• W3201452605 cites W2055262503 @default.
• W3201452605 cites W2056536841 @default.
• W3201452605 cites W2058592348 @default.
• W3201452605 cites W2060263213 @default.
• W3201452605 cites W2065078838 @default.
• W3201452605 cites W2067927054 @default.
• W3201452605 cites W2069656614 @default.
• W3201452605 cites W2091403824 @default.
• W3201452605 cites W2113662018 @default.
• W3201452605 cites W2134205767 @default.
• W3201452605 cites W2138025841 @default.
• W3201452605 cites W2165661552 @default.
• W3201452605 cites W2258353357 @default.
• W3201452605 cites W2269315630 @default.
• W3201452605 cites W240686710 @default.
• W3201452605 cites W2476290316 @default.
• W3201452605 cites W2520476796 @default.
• W3201452605 cites W2520799412 @default.
• W3201452605 cites W2547000105 @default.
• W3201452605 cites W2556959132 @default.
• W3201452605 cites W2592642890 @default.
• W3201452605 cites W2616514904 @default.
• W3201452605 cites W2733096218 @default.
• W3201452605 cites W2745088377 @default.
• W3201452605 cites W2780820000 @default.
• W3201452605 cites W2793719339 @default.
• W3201452605 cites W2800606186 @default.
• W3201452605 cites W2808512344 @default.
• W3201452605 cites W2810235423 @default.
• W3201452605 cites W2811536948 @default.
• W3201452605 cites W2885357008 @default.
• W3201452605 cites W2905765253 @default.
• W3201452605 cites W2907173452 @default.
• W3201452605 cites W2913146335 @default.
• W3201452605 cites W2948266692 @default.
• W3201452605 cites W2968180545 @default.
• W3201452605 cites W2997242099 @default.
• W3201452605 cites W3011787004 @default.
• W3201452605 cites W3017845175 @default.
• W3201452605 cites W3018666705 @default.
• W3201452605 cites W3026448445 @default.
• W3201452605 cites W3029885011 @default.
• W3201452605 cites W3036157613 @default.
• W3201452605 cites W3084729216 @default.
• W3201452605 cites W3092159146 @default.
• W3201452605 cites W3164970319 @default.
• W3201452605 cites W3176731164 @default.
• W3201452605 cites W3177016342 @default.
• W3201452605 cites W3178904319 @default.
• W3201452605 cites W4250284053 @default.
• W3201452605 doi "https://doi.org/10.3390/biomedicines9091206" @default.
• W3201452605 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/8465604" @default.
• W3201452605 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/34572392" @default.
• W3201452605 hasPublicationYear "2021" @default.
• W3201452605 type Work @default.
• W3201452605 sameAs 3201452605 @default.
• W3201452605 citedByCount "4" @default.
• W3201452605 countsByYear W32014526052022 @default.
• W3201452605 countsByYear W32014526052023 @default.
• W3201452605 crossrefType "journal-article" @default.
• W3201452605 hasAuthorship W3201452605A5001768226 @default.
• W3201452605 hasAuthorship W3201452605A5006573657 @default.
• W3201452605 hasAuthorship W3201452605A5017004450 @default.
• W3201452605 hasAuthorship W3201452605A5017246332 @default.
• W3201452605 hasAuthorship W3201452605A5017342414 @default.
• W3201452605 hasAuthorship W3201452605A5035499944 @default.

• next