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- W3201479837 endingPage "3828" @default.
- W3201479837 startingPage "3813" @default.
- W3201479837 abstract "COVID-19, a type of viral pneumonia caused by severe acute respiratory syndrome coronavirus 2 has challenged the world as global pandemic. It has marked the identification of third generation of extremely pathogenic zoonotic coronaviruses of twenty-first century posing threat to humans and mainly targeting the lower respiratory tract. In this review, we focused on not only the structure and virology of SARS-COV-2 but have discussed in detail the molecular immunopathogenesis of this novel virus highlighting its interaction with immune system and the role of compromised or dysregulated immune response towards disease severity. We attempted to correlate the crosstalk between unregulated inflammatory outcomes with disrupted host immunity which may play a potential role towards fatal acute respiratory distress syndrome that claims to be life-threatening in COVID-19. Exploration and investigation of molecular host-virus interactions will provide a better understanding on the mechanism of fatal COVID-19 infection and also enlighten the escape routes from the same." @default.
- W3201479837 created "2021-09-27" @default.
- W3201479837 creator A5011365211 @default.
- W3201479837 creator A5013455547 @default.
- W3201479837 creator A5034287533 @default.
- W3201479837 date "2021-09-22" @default.
- W3201479837 modified "2023-10-01" @default.
- W3201479837 title "Molecular Insights into the Crosstalk Between Immune Inflammation Nexus and SARS-CoV-2 Virus" @default.
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