FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W3201491582> ?p ?o ?g. }

• W3201491582 endingPage "113663" @default.
• W3201491582 startingPage "113663" @default.
• W3201491582 abstract "Tuberculosis (TB) remains the high-risk infectious pathogen that caused global pandemic and high mortality, particularly in the areas lack in health resources. Clinical TB screening and diagnosis are so far mainly conducted on limited types of commercial platforms, which are expensive and require skilled personnel. In this work, we introduced a low-cost and portable finger-driven microfluidic chip (named Fd-MC) based on recombinase polymerase amplification (RPA) for rapid on-site detection of TB. After injection of the pre-treated sample solution, the pre-packaged buffer was driven by the pressure generated by the finger-actuated operation to accomplish sequential processes of diagnosis in a fully isolated microchannel. An in-situ fluorescence strategy based on FAM-probe was implemented for on-chip results read-out though a hand-held UV lamp. Hence, the Fd-MC proved unique advantageous for avoiding the risk of infection or environmental contamination. In addition, the Fd-MC was designed for multiplexed detection, which is able to not only identify TB/non-TB infection, but also differentiate between human Mycobacterium tuberculosis and Mycobacterium bovis. The platform was verified in 37 clinical samples, statistically with 100% specificity and 95.2% sensitivity as compared to commercial real-time RPA. Overall, the proposed platform eliminates the need on external pumps and skilled personnel, holding promise to POC testing in the resource-limited area." @default.
• W3201491582 created "2021-09-27" @default.
• W3201491582 creator A5000693841 @default.
• W3201491582 creator A5003642180 @default.
• W3201491582 creator A5031087363 @default.
• W3201491582 creator A5034367719 @default.
• W3201491582 creator A5047295889 @default.
• W3201491582 creator A5055149792 @default.
• W3201491582 creator A5077695586 @default.
• W3201491582 date "2022-01-01" @default.
• W3201491582 modified "2023-10-17" @default.
• W3201491582 title "A finger-driven disposable micro-platform based on isothermal amplification for the application of multiplexed and point-of-care diagnosis of tuberculosis" @default.
• W3201491582 cites W1976252882 @default.
• W3201491582 cites W1986080495 @default.
• W3201491582 cites W2039310908 @default.
• W3201491582 cites W2041657167 @default.
• W3201491582 cites W2049653805 @default.
• W3201491582 cites W2055141898 @default.
• W3201491582 cites W2061932947 @default.
• W3201491582 cites W2072212493 @default.
• W3201491582 cites W2074826409 @default.
• W3201491582 cites W2080061019 @default.
• W3201491582 cites W2111922564 @default.
• W3201491582 cites W2141012160 @default.
• W3201491582 cites W2159773654 @default.
• W3201491582 cites W2266986848 @default.
• W3201491582 cites W2381611646 @default.
• W3201491582 cites W2399057498 @default.
• W3201491582 cites W2418180773 @default.
• W3201491582 cites W2515222185 @default.
• W3201491582 cites W2603064466 @default.
• W3201491582 cites W2605288157 @default.
• W3201491582 cites W2745419473 @default.
• W3201491582 cites W2766802619 @default.
• W3201491582 cites W2766989075 @default.
• W3201491582 cites W2771791410 @default.
• W3201491582 cites W2781735920 @default.
• W3201491582 cites W2789767203 @default.
• W3201491582 cites W2791748480 @default.
• W3201491582 cites W2809341244 @default.
• W3201491582 cites W2886461107 @default.
• W3201491582 cites W2936803404 @default.
• W3201491582 cites W2944770028 @default.
• W3201491582 cites W2950672457 @default.
• W3201491582 cites W2966056094 @default.
• W3201491582 cites W2968377049 @default.
• W3201491582 cites W2979611309 @default.
• W3201491582 cites W2982604016 @default.
• W3201491582 cites W2997077129 @default.
• W3201491582 cites W3017734555 @default.
• W3201491582 cites W3024995036 @default.
• W3201491582 cites W3026431994 @default.
• W3201491582 cites W3033346096 @default.
• W3201491582 cites W3089242181 @default.
• W3201491582 cites W3090882943 @default.
• W3201491582 cites W3091127702 @default.
• W3201491582 cites W3116495303 @default.
• W3201491582 cites W3117019926 @default.
• W3201491582 cites W3132711590 @default.
• W3201491582 cites W3152087952 @default.
• W3201491582 doi "https://doi.org/10.1016/j.bios.2021.113663" @default.
• W3201491582 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/34610534" @default.
• W3201491582 hasPublicationYear "2022" @default.
• W3201491582 type Work @default.
• W3201491582 sameAs 3201491582 @default.
• W3201491582 citedByCount "22" @default.
• W3201491582 countsByYear W32014915822022 @default.
• W3201491582 countsByYear W32014915822023 @default.
• W3201491582 crossrefType "journal-article" @default.
• W3201491582 hasAuthorship W3201491582A5000693841 @default.
• W3201491582 hasAuthorship W3201491582A5003642180 @default.
• W3201491582 hasAuthorship W3201491582A5031087363 @default.
• W3201491582 hasAuthorship W3201491582A5034367719 @default.
• W3201491582 hasAuthorship W3201491582A5047295889 @default.
• W3201491582 hasAuthorship W3201491582A5055149792 @default.
• W3201491582 hasAuthorship W3201491582A5077695586 @default.
• W3201491582 hasConcept C136229726 @default.
• W3201491582 hasConcept C139713532 @default.
• W3201491582 hasConcept C142724271 @default.
• W3201491582 hasConcept C171250308 @default.
• W3201491582 hasConcept C192562407 @default.
• W3201491582 hasConcept C19275194 @default.
• W3201491582 hasConcept C2777975735 @default.
• W3201491582 hasConcept C2781069245 @default.
• W3201491582 hasConcept C41008148 @default.
• W3201491582 hasConcept C51915194 @default.
• W3201491582 hasConcept C54355233 @default.
• W3201491582 hasConcept C552990157 @default.
• W3201491582 hasConcept C60635243 @default.
• W3201491582 hasConcept C71924100 @default.
• W3201491582 hasConcept C76155785 @default.
• W3201491582 hasConcept C8673954 @default.
• W3201491582 hasConcept C86803240 @default.
• W3201491582 hasConceptScore W3201491582C136229726 @default.
• W3201491582 hasConceptScore W3201491582C139713532 @default.
• W3201491582 hasConceptScore W3201491582C142724271 @default.
• W3201491582 hasConceptScore W3201491582C171250308 @default.
• W3201491582 hasConceptScore W3201491582C192562407 @default.

• next