Matches in SemOpenAlex for { <https://semopenalex.org/work/W3201501342> ?p ?o ?g. }
Showing items 1 to 81 of
81
with 100 items per page.
- W3201501342 abstract "Introduction: The FOXP3 protein is an immune regulatory protein that specifically maintains the function and differentiation of regulatory T cells (Tregs) and prevents autoimmunity. Variations in FOXP3 gene may alter its function and also the immune response. Objectives: The present study was conducted to investigate the association of the FOXP3 gene polymorphisms -3499 A/G and -3279 A/C with renal allograft function and survival in kidney transplant recipients. Patients and Methods: In this cross-sectional study, 150 eligible kidney transplant recipients were evaluated. Kidney function was evaluated at three- and five-year post-transplant using serum creatinine level and glomerular filtration rate as indicators. Genotyping of the study participants was performed using the PCR– restriction fragment length polymorphism method. Results: The frequencies of AA, AG, and GG genotypes of the -3499 A/G polymorphism were 62.42%, 29.53%, and 8.05%, respectively. For the -3279 A/C polymorphism, the frequencies of the AA, AC, and CC genotypes were 21.33%, 32%, and 46.67%, respectively. The mean ± SD of serum creatinine level, three and five years after transplantation were 1.70 ± 1.58 and 1.87 ± 1.94, respectively. Serum creatinine level and kidney function did not show any significant association with these polymorphisms. Conclusion: In the present study, only 10% of participants experienced episodes of severe kidney dysfunction and we did not find any significant association between kidney function and the subjects’ genotypes. Further epidemiologic studies with greater sample sizes may be needed to clarify this association." @default.
- W3201501342 created "2021-09-27" @default.
- W3201501342 creator A5007403377 @default.
- W3201501342 creator A5024158320 @default.
- W3201501342 creator A5024479644 @default.
- W3201501342 creator A5026943708 @default.
- W3201501342 creator A5031911085 @default.
- W3201501342 creator A5032468621 @default.
- W3201501342 creator A5033866063 @default.
- W3201501342 creator A5038665351 @default.
- W3201501342 creator A5069815223 @default.
- W3201501342 date "2020-11-02" @default.
- W3201501342 modified "2023-10-16" @default.
- W3201501342 title "The association of two single-nucleotide polymorphisms of the FOXP3 gene (rs3761548 and rs3761547) with renal allograft function and survival in kidney transplant recipients" @default.
- W3201501342 doi "https://doi.org/10.34172/ipp.2021.21" @default.
- W3201501342 hasPublicationYear "2020" @default.
- W3201501342 type Work @default.
- W3201501342 sameAs 3201501342 @default.
- W3201501342 citedByCount "0" @default.
- W3201501342 crossrefType "journal-article" @default.
- W3201501342 hasAuthorship W3201501342A5007403377 @default.
- W3201501342 hasAuthorship W3201501342A5024158320 @default.
- W3201501342 hasAuthorship W3201501342A5024479644 @default.
- W3201501342 hasAuthorship W3201501342A5026943708 @default.
- W3201501342 hasAuthorship W3201501342A5031911085 @default.
- W3201501342 hasAuthorship W3201501342A5032468621 @default.
- W3201501342 hasAuthorship W3201501342A5033866063 @default.
- W3201501342 hasAuthorship W3201501342A5038665351 @default.
- W3201501342 hasAuthorship W3201501342A5069815223 @default.
- W3201501342 hasBestOaLocation W32015013421 @default.
- W3201501342 hasConcept C104317684 @default.
- W3201501342 hasConcept C126322002 @default.
- W3201501342 hasConcept C135763542 @default.
- W3201501342 hasConcept C153209595 @default.
- W3201501342 hasConcept C159641895 @default.
- W3201501342 hasConcept C203014093 @default.
- W3201501342 hasConcept C2779727006 @default.
- W3201501342 hasConcept C2780091579 @default.
- W3201501342 hasConcept C2780303639 @default.
- W3201501342 hasConcept C2780306776 @default.
- W3201501342 hasConcept C2911091166 @default.
- W3201501342 hasConcept C31467283 @default.
- W3201501342 hasConcept C54355233 @default.
- W3201501342 hasConcept C71924100 @default.
- W3201501342 hasConcept C86803240 @default.
- W3201501342 hasConcept C8891405 @default.
- W3201501342 hasConcept C90924648 @default.
- W3201501342 hasConceptScore W3201501342C104317684 @default.
- W3201501342 hasConceptScore W3201501342C126322002 @default.
- W3201501342 hasConceptScore W3201501342C135763542 @default.
- W3201501342 hasConceptScore W3201501342C153209595 @default.
- W3201501342 hasConceptScore W3201501342C159641895 @default.
- W3201501342 hasConceptScore W3201501342C203014093 @default.
- W3201501342 hasConceptScore W3201501342C2779727006 @default.
- W3201501342 hasConceptScore W3201501342C2780091579 @default.
- W3201501342 hasConceptScore W3201501342C2780303639 @default.
- W3201501342 hasConceptScore W3201501342C2780306776 @default.
- W3201501342 hasConceptScore W3201501342C2911091166 @default.
- W3201501342 hasConceptScore W3201501342C31467283 @default.
- W3201501342 hasConceptScore W3201501342C54355233 @default.
- W3201501342 hasConceptScore W3201501342C71924100 @default.
- W3201501342 hasConceptScore W3201501342C86803240 @default.
- W3201501342 hasConceptScore W3201501342C8891405 @default.
- W3201501342 hasConceptScore W3201501342C90924648 @default.
- W3201501342 hasLocation W32015013421 @default.
- W3201501342 hasOpenAccess W3201501342 @default.
- W3201501342 hasPrimaryLocation W32015013421 @default.
- W3201501342 hasRelatedWork W1571661066 @default.
- W3201501342 hasRelatedWork W1975362039 @default.
- W3201501342 hasRelatedWork W1984544009 @default.
- W3201501342 hasRelatedWork W2087086071 @default.
- W3201501342 hasRelatedWork W2277608930 @default.
- W3201501342 hasRelatedWork W2315119463 @default.
- W3201501342 hasRelatedWork W2370331116 @default.
- W3201501342 hasRelatedWork W2392082400 @default.
- W3201501342 hasRelatedWork W3031554177 @default.
- W3201501342 hasRelatedWork W3031966738 @default.
- W3201501342 isParatext "false" @default.
- W3201501342 isRetracted "false" @default.
- W3201501342 magId "3201501342" @default.
- W3201501342 workType "article" @default.