Matches in SemOpenAlex for { <https://semopenalex.org/work/W3201566701> ?p ?o ?g. }
- W3201566701 endingPage "280" @default.
- W3201566701 startingPage "249" @default.
- W3201566701 abstract "Mild neuroinflammation is a neuroprotective process in response to infection or injury contributing to homeostasis and repair process. However, uncontrolled chronic neuroinflammation is a pathogenic process, which is promoted by the activation of microglia and astrocytes. Activation of microglia and astrocytes produces a series of pro-inflammatory and cytotoxic factors, such as iNOS, COX-2, TNF-α, IL-1β, and IL-6. These cytokines cause neuronal damage and eventually cell death. Available drugs for suppressing neuroinflammation include steroids, nonsteroid antiinflammatory drugs, and immunosuppressants. These drugs produce many harmful effects. Phytochemicals are natural metabolites, which are derived from natural herbs and plants. They are sources of alternative medications, which are safe, effective, and low-cost medicines for the suppression of neuroinflammation in animal and humans. They produce antineuroinflammatory effects by modulating NF-κB, MAPKs, STAT, and Nrf2 signaling pathways." @default.
- W3201566701 created "2021-09-27" @default.
- W3201566701 creator A5018817311 @default.
- W3201566701 date "2022-01-01" @default.
- W3201566701 modified "2023-09-23" @default.
- W3201566701 title "Prevention of neuroinflammation and resolution by phytochemicals" @default.
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