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- W3201604801 abstract "Real time controllable assembling/aptasensing approach via plasmonic graphene oxide (GO) nanocomposites has been firstly proven to simultaneously give tuning of micro-nano structure of plasmonic GO and ultrasensitive detection of MC-LR toxin. In order to fabricate the assembly, a high-quality hollow triangular nanoplate AgClAu:p-GO (HTNP AgClAu:p-GO) can act as a template; furthermore, we combine DNA-hybridization with biotin-strepavidin binding protocol for tuning the HTNP AgClAu:p-GO assemblies from networks to laminar structure, and simultaneously loading Raman reporters into the assemblies. The dynamic assembling process can be utilized as a real time SERS aptasensor for detecting MC-LR due to ratiometric introduction of MC-LR toxin inhibiting formation of plasmonic p-GO assembly via toxin/aptamer bioconjugation and causing reverse alteration of SERS signal for giving ultrasensitive SERS detection of MC-LR. A detection limit of 6.3pM with a wide linear range from 10pM to 5 nM can be achieved. When the aptasensor has been applied in real samples, the real time assembling/aptasensing approach shows recoveries from 98% to 103% with relative standard deviation (RSD) lower than 3%, expecting that one-step nanofabrication and sensing strategy can be extended to in-field test of environmental contaminants." @default.
- W3201604801 created "2021-09-27" @default.
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- W3201604801 date "2022-01-01" @default.
- W3201604801 modified "2023-09-27" @default.
- W3201604801 title "A facile ultrasensitive detection of MC-LR toxin via a real-time assembled aptasensor of plasmonic graphene oxide" @default.
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- W3201604801 doi "https://doi.org/10.1016/j.talanta.2021.122864" @default.
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