Matches in SemOpenAlex for { <https://semopenalex.org/work/W3201608529> ?p ?o ?g. }
- W3201608529 endingPage "326" @default.
- W3201608529 startingPage "313" @default.
- W3201608529 abstract "Abstract Glioblastoma remains lethal even when treated with standard therapy. This review aims to outline the recent development of various advanced therapeutics for glioblastoma and briefly discuss the potential impact of glioblastoma and some of its therapeutic approaches on the neurological function micturition control. Although immunotherapy led to success in treating hematological malignancies, but no similar success occurred in treatment for brain glioblastoma. Neither regenerative medicine nor stem cell therapy led to astounding success in glioblastoma. However, CRISPR Cas system holds potential in multiple applications due to its capacity to knock-in and knock-out genes, modify immune cells and cell receptors, which will enable it to address clinical challenges in immunotherapy such as CAR-T and regenerative therapy for brain glioblastoma, improving the precision and safety of these approaches. The studies mentioned in this review could indicate that glioblastoma is a malignant disease with multiple sophisticated barriers to be overcome and more challenges might arise in the attempt of researchers to yield a successful cure. A multimodal approach of future generation of refined and safe therapeutics derived from CRISPR Cas therapeutics, immunotherapy, and regenerative therapeutics mentioned in this review might prolong survival or even contribute towards a potential cure for glioblastoma." @default.
- W3201608529 created "2021-09-27" @default.
- W3201608529 creator A5011071284 @default.
- W3201608529 creator A5027832181 @default.
- W3201608529 creator A5078196849 @default.
- W3201608529 date "2021-09-16" @default.
- W3201608529 modified "2023-10-18" @default.
- W3201608529 title "Future generation of combined multimodal approach to treat brain glioblastoma multiforme and potential impact on micturition control" @default.
- W3201608529 cites W1482109403 @default.
- W3201608529 cites W1514125758 @default.
- W3201608529 cites W1536219359 @default.
- W3201608529 cites W1569982723 @default.
- W3201608529 cites W1594827615 @default.
- W3201608529 cites W1692777765 @default.
- W3201608529 cites W1788555665 @default.
- W3201608529 cites W1879322546 @default.
- W3201608529 cites W1911456703 @default.
- W3201608529 cites W1951128322 @default.
- W3201608529 cites W1965398961 @default.
- W3201608529 cites W1965411082 @default.
- W3201608529 cites W1967600348 @default.
- W3201608529 cites W1989696297 @default.
- W3201608529 cites W1992246726 @default.
- W3201608529 cites W1992985027 @default.
- W3201608529 cites W1998558441 @default.
- W3201608529 cites W2005426031 @default.
- W3201608529 cites W2007753570 @default.
- W3201608529 cites W2010770435 @default.
- W3201608529 cites W2011940955 @default.
- W3201608529 cites W2012807675 @default.
- W3201608529 cites W2015180126 @default.
- W3201608529 cites W2016821076 @default.
- W3201608529 cites W2017467835 @default.
- W3201608529 cites W2018117162 @default.
- W3201608529 cites W2020017623 @default.
- W3201608529 cites W2020821895 @default.
- W3201608529 cites W2022308075 @default.
- W3201608529 cites W2028460943 @default.
- W3201608529 cites W2032281007 @default.
- W3201608529 cites W2033678007 @default.
- W3201608529 cites W2039721940 @default.
- W3201608529 cites W2041491651 @default.
- W3201608529 cites W2042868415 @default.
- W3201608529 cites W2044337953 @default.
- W3201608529 cites W2045435533 @default.
- W3201608529 cites W2052424792 @default.
- W3201608529 cites W2064815984 @default.
- W3201608529 cites W2065617830 @default.
- W3201608529 cites W2067131837 @default.
- W3201608529 cites W2067856703 @default.
- W3201608529 cites W2077572566 @default.
- W3201608529 cites W2081872121 @default.
- W3201608529 cites W2083172345 @default.
- W3201608529 cites W2092142572 @default.
- W3201608529 cites W2094945699 @default.
- W3201608529 cites W2096287682 @default.
- W3201608529 cites W2104759721 @default.
- W3201608529 cites W2108119601 @default.
- W3201608529 cites W2110099116 @default.
- W3201608529 cites W2110399041 @default.
- W3201608529 cites W2111237964 @default.
- W3201608529 cites W2124929662 @default.
- W3201608529 cites W2128085444 @default.
- W3201608529 cites W2134803598 @default.
- W3201608529 cites W2138909102 @default.
- W3201608529 cites W2140088548 @default.
- W3201608529 cites W2144120657 @default.
- W3201608529 cites W2144649295 @default.
- W3201608529 cites W2145544530 @default.
- W3201608529 cites W2145689707 @default.
- W3201608529 cites W2154115071 @default.
- W3201608529 cites W2156229286 @default.
- W3201608529 cites W2157769714 @default.
- W3201608529 cites W2158128644 @default.
- W3201608529 cites W2158953873 @default.
- W3201608529 cites W2159948826 @default.
- W3201608529 cites W2161289668 @default.
- W3201608529 cites W2164384962 @default.
- W3201608529 cites W2166662937 @default.
- W3201608529 cites W2167351436 @default.
- W3201608529 cites W2173968248 @default.
- W3201608529 cites W2192976324 @default.
- W3201608529 cites W2199695484 @default.
- W3201608529 cites W2293496672 @default.
- W3201608529 cites W2315693860 @default.
- W3201608529 cites W2325421340 @default.
- W3201608529 cites W2335365056 @default.
- W3201608529 cites W2347191528 @default.
- W3201608529 cites W2366536035 @default.
- W3201608529 cites W2392045628 @default.
- W3201608529 cites W2400116375 @default.
- W3201608529 cites W2416228289 @default.
- W3201608529 cites W2521918372 @default.
- W3201608529 cites W2528173482 @default.
- W3201608529 cites W2548694234 @default.
- W3201608529 cites W2567424265 @default.
- W3201608529 cites W2569050105 @default.
- W3201608529 cites W2572765595 @default.