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- W3201617373 abstract "Traumatic spinal cord injuries (SCIs) have far-reaching physical, social, and financial consequences. While medical advancements have improved supportive therapeutic measures for SCI patients, no effective neuroregenerative therapeutic options exist to date. Instead, the paradigm of SCI therapy is inevitably directed towards damage control rather than the restoration of a state of functional independence. Facing a continuous increase in the prevalence of spinal cord injured patients, neuroprotective and neuroregenerative strategies have earned tremendous scientific interest. This review intends to provide a robust summary of the most promising neuroprotective and neuroregenerative therapies currently under investigation. While we highlight encouraging neuroprotective strategies as well, the focus of this review lies on neuroregenerative therapies, including neuropharmacological and cell-based approaches. We finally point to the exciting investigational areas of biomaterial scaffolds and neuromodulation therapies." @default.
- W3201617373 created "2021-09-27" @default.
- W3201617373 creator A5048958970 @default.
- W3201617373 creator A5070195374 @default.
- W3201617373 date "2021-10-01" @default.
- W3201617373 modified "2023-10-18" @default.
- W3201617373 title "A review of emerging neuroprotective and neuroregenerative therapies in traumatic spinal cord injury" @default.
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- W3201617373 doi "https://doi.org/10.1016/j.coph.2021.08.009" @default.
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