FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W3201634732> ?p ?o ?g. }

• W3201634732 endingPage "66" @default.
• W3201634732 startingPage "61" @default.
• W3201634732 abstract "Brugada syndrome is a rare inherited arrhythmic syndrome with a coved type 1 ST-segment elevation on ECG and an increased risk of sudden death. Many studies have evaluated risk stratification performance based on ECG-derived parameters. However, since historical Brugada patient cohorts included mostly paper ECGs, most studies have been based on manual ECG parameter measurements. We hypothesized that it would be possible to run automated algorithm-based analysis of paper ECGs. We aimed: 1) to validate the digitization process for paper ECGs in Brugada patients; and 2) to quantify the acute class I antiarrhythmic drug effect on relevant ECG parameters in Brugada syndrome.A total of 176 patients (30% female, 43 ± 13 years old) with induced type 1 Brugada syndrome ECG were included in the study. All of the patients had paper ECGs before and during class I antiarrhythmic drug challenge. Twenty patients also had a digital ECG, in whom printouts were used to validate the digitization process. Paper ECGs were scanned and then digitized using ECGScan software, version 3.4.0 (AMPS, LLC, New York, NY, USA) to obtain FDA HL7 XML format ECGs. Measurements were automatically performed using the Bravo (AMPS, LLC, New York, NY, USA) and Glasgow algorithms.ECG parameters obtained from digital and digitized ECGs were closely correlated (r = 0.96 ± 0.07, R2 = 0.93 ± 0.12). Class I antiarrhythmic drugs significantly increased the global QRS duration (from 113 ± 20 to 138 ± 23, p < 0.0001). On lead V2, class I antiarrhythmic drugs increased ST-segment elevation (from 110 ± 84 to 338 ± 227 μV, p < 0.0001), decreased the ST slope (from 14.9 ± 23.3 to -27.4 ± 28.5, p < 0.0001) and increased the TpTe interval (from 88 ± 18 to 104 ± 33, p < 0.0001).Automated algorithm-based measurements of depolarization and repolarization parameters from digitized paper ECGs are reliable and could quantify the acute effects of class 1 antiarrhythmic drug challenge in Brugada patients. Our results support using computerized automated algorithm-based analyses from digitized paper ECGs to establish risk stratification decision trees in Brugada syndrome." @default.
• W3201634732 created "2021-09-27" @default.
• W3201634732 creator A5018607116 @default.
• W3201634732 creator A5019450757 @default.
• W3201634732 creator A5034036432 @default.
• W3201634732 creator A5051740188 @default.
• W3201634732 creator A5053290257 @default.
• W3201634732 creator A5067349282 @default.
• W3201634732 creator A5068434310 @default.
• W3201634732 date "2021-11-01" @default.
• W3201634732 modified "2023-10-12" @default.
• W3201634732 title "Computerized automated algorithm-based analyses of digitized paper ECGs in Brugada syndrome" @default.
• W3201634732 cites W1968209580 @default.
• W3201634732 cites W1997696957 @default.
• W3201634732 cites W2013450234 @default.
• W3201634732 cites W2034863927 @default.
• W3201634732 cites W2122198208 @default.
• W3201634732 cites W2146227751 @default.
• W3201634732 cites W2520977877 @default.
• W3201634732 cites W2582102633 @default.
• W3201634732 cites W2599761051 @default.
• W3201634732 cites W2604359798 @default.
• W3201634732 cites W2737207910 @default.
• W3201634732 cites W2758659079 @default.
• W3201634732 cites W2948569452 @default.
• W3201634732 cites W2972758116 @default.
• W3201634732 cites W2985333116 @default.
• W3201634732 cites W3081821382 @default.
• W3201634732 cites W3120773450 @default.
• W3201634732 doi "https://doi.org/10.1016/j.jelectrocard.2021.09.009" @default.
• W3201634732 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/34563332" @default.
• W3201634732 hasPublicationYear "2021" @default.
• W3201634732 type Work @default.
• W3201634732 sameAs 3201634732 @default.
• W3201634732 citedByCount "0" @default.
• W3201634732 crossrefType "journal-article" @default.
• W3201634732 hasAuthorship W3201634732A5018607116 @default.
• W3201634732 hasAuthorship W3201634732A5019450757 @default.
• W3201634732 hasAuthorship W3201634732A5034036432 @default.
• W3201634732 hasAuthorship W3201634732A5051740188 @default.
• W3201634732 hasAuthorship W3201634732A5053290257 @default.
• W3201634732 hasAuthorship W3201634732A5067349282 @default.
• W3201634732 hasAuthorship W3201634732A5068434310 @default.
• W3201634732 hasBestOaLocation W32016347321 @default.
• W3201634732 hasConcept C111773187 @default.
• W3201634732 hasConcept C11413529 @default.
• W3201634732 hasConcept C126322002 @default.
• W3201634732 hasConcept C164705383 @default.
• W3201634732 hasConcept C2771771 @default.
• W3201634732 hasConcept C2775935837 @default.
• W3201634732 hasConcept C2777382798 @default.
• W3201634732 hasConcept C2780040984 @default.
• W3201634732 hasConcept C3020404979 @default.
• W3201634732 hasConcept C41008148 @default.
• W3201634732 hasConcept C500558357 @default.
• W3201634732 hasConcept C71924100 @default.
• W3201634732 hasConceptScore W3201634732C111773187 @default.
• W3201634732 hasConceptScore W3201634732C11413529 @default.
• W3201634732 hasConceptScore W3201634732C126322002 @default.
• W3201634732 hasConceptScore W3201634732C164705383 @default.
• W3201634732 hasConceptScore W3201634732C2771771 @default.
• W3201634732 hasConceptScore W3201634732C2775935837 @default.
• W3201634732 hasConceptScore W3201634732C2777382798 @default.
• W3201634732 hasConceptScore W3201634732C2780040984 @default.
• W3201634732 hasConceptScore W3201634732C3020404979 @default.
• W3201634732 hasConceptScore W3201634732C41008148 @default.
• W3201634732 hasConceptScore W3201634732C500558357 @default.
• W3201634732 hasConceptScore W3201634732C71924100 @default.
• W3201634732 hasLocation W32016347321 @default.
• W3201634732 hasLocation W32016347322 @default.
• W3201634732 hasLocation W32016347323 @default.
• W3201634732 hasOpenAccess W3201634732 @default.
• W3201634732 hasPrimaryLocation W32016347321 @default.
• W3201634732 hasRelatedWork W2020544432 @default.
• W3201634732 hasRelatedWork W2181479204 @default.
• W3201634732 hasRelatedWork W2192619873 @default.
• W3201634732 hasRelatedWork W2418904649 @default.
• W3201634732 hasRelatedWork W2746438284 @default.
• W3201634732 hasRelatedWork W2810192095 @default.
• W3201634732 hasRelatedWork W3035986844 @default.
• W3201634732 hasRelatedWork W3163804420 @default.
• W3201634732 hasRelatedWork W3208984736 @default.
• W3201634732 hasRelatedWork W2185852853 @default.
• W3201634732 hasVolume "69" @default.
• W3201634732 isParatext "false" @default.
• W3201634732 isRetracted "false" @default.
• W3201634732 magId "3201634732" @default.
• W3201634732 workType "article" @default.