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- W3201700502 endingPage "951" @default.
- W3201700502 startingPage "951" @default.
- W3201700502 abstract "With the increasing incidence of skin cancer, many noninvasive technologies to detect its presence have been developed. This review focuses on reflectance confocal microscopy (RCM), optical coherence tomography (OCT), high-frequency ultrasound (HFUS), electrical impedance spectroscopy (EIS), pigmented lesion assay (PLA), and Raman spectroscopy (RS) and discusses the basic principle, clinical applications, advantages, and disadvantages of each technology. RCM provides high cellular resolution and has high sensitivity and specificity for the diagnosis of skin cancer. OCT provides lower resolution than RCM, although its evaluable depth is deeper than that of RCM. RCM and OCT may be useful in reducing the number of unnecessary biopsies, evaluating the tumor margin, and monitoring treatment response. HFUS can be mainly used to delineate tumor depths or margins and monitor the treatment response. EIS provides high sensitivity but low specificity for the diagnosis of skin malignancies. PLA, which is based on the genetic information of lesions, is applicable for the detection of melanoma with high sensitivity and moderate-to-high specificity. RS showed high accuracy for the diagnosis of skin cancer, although more clinical studies are required. Advances in these technologies for the diagnosis of skin cancer can lead to the realization of optimized and individualized treatments." @default.
- W3201700502 created "2021-10-11" @default.
- W3201700502 creator A5003308494 @default.
- W3201700502 creator A5010489738 @default.
- W3201700502 creator A5021865337 @default.
- W3201700502 creator A5057582488 @default.
- W3201700502 creator A5070738695 @default.
- W3201700502 creator A5075658511 @default.
- W3201700502 date "2021-09-24" @default.
- W3201700502 modified "2023-09-30" @default.
- W3201700502 title "Emerging Minimally Invasive Technologies for the Detection of Skin Cancer" @default.
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