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- W3201702481 abstract "Oral mucositis is a debilitating oncology treatment side effect, with honey identified as a viable management option due to established wound-healing abilities. However, effects of saliva on properties attributed to honey's wound-healing abilities is unknown. Therefore, this study aimed to identify interactions between saliva, and antioxidant characteristics and pH of honey.Saliva was collected from 15 healthy participants (Females n=9; mean age=34.1 ± 11.2 years). Centrifuged salivary supernatant, whole saliva, and water were independently used to dilute commercial Australian honeys (n=42). Antioxidant characteristics (DPPH and FRAP) and pH of diluted honeys were analysed, and differences between dilution conditions were determined.Honey and saliva dilutions increased antioxidant characteristics compared to water, and addition of honey to saliva reduced pH compared with saliva alone. There were significant differences between dilutions for FRAP and pH, and water and salivary conditions for DPPH (p<0.001). No difference was observed between salivary conditions for DPPH (p=0.931), suggesting smaller cells remaining in the supernatant possess antioxidant abilities. However, differences observed for FRAP suggest precipitable molecules, including epithelial and food debris, could provide additional antioxidant power.The addition of saliva to honey may support properties attributed to honey's wound-healing abilities and should be considered in the context of oral mucositis management." @default.
- W3201702481 created "2021-10-11" @default.
- W3201702481 creator A5008363237 @default.
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- W3201702481 date "2021-09-29" @default.
- W3201702481 modified "2023-10-17" @default.
- W3201702481 title "Interaction between properties of commercial Australian honey and saliva: <i>in vitro</i> exploratory study of a potential mechanism in the treatment of oral mucositis" @default.
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- W3201702481 doi "https://doi.org/10.1515/jcim-2021-0280" @default.
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