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- W3201749743 abstract "Chimeric antigen receptor T (CAR-T) cell therapy achieved extraordinary achievements results in antitumor treatments, especially against hematological malignancies, where it leads to remarkable, long-term antineoplastic effects with higher target specificity. Nevertheless, some limitations persist in autologous CAR-T cell therapy, such as high costs, long manufacturing periods, and restricted cell sources. The development of a universal CAR-T (UCAR-T) cell therapy is an attractive breakthrough point that may overcome most of these drawbacks. Here, we review the progress and challenges in CAR-T cell therapy, especially focusing on comprehensive comparison in UCAR-T cell therapy to original CAR-T cell therapy. Furthermore, we summarize the developments and concerns about the safety and efficiency of UCAR-T cell therapy. Finally, we address other immune cells, which might be promising candidates as a complement for UCAR-T cells. Through a detailed overview, we describe the current landscape and explore the prospect of UCAR-T cell therapy." @default.
- W3201749743 created "2021-10-11" @default.
- W3201749743 creator A5021606010 @default.
- W3201749743 creator A5023855870 @default.
- W3201749743 creator A5025106342 @default.
- W3201749743 creator A5030403651 @default.
- W3201749743 creator A5057943832 @default.
- W3201749743 date "2021-10-06" @default.
- W3201749743 modified "2023-10-14" @default.
- W3201749743 title "Advances in Universal CAR-T Cell Therapy" @default.
- W3201749743 cites W1605124125 @default.
- W3201749743 cites W1839053269 @default.
- W3201749743 cites W1881216623 @default.
- W3201749743 cites W1976400767 @default.
- W3201749743 cites W1991494425 @default.
- W3201749743 cites W2002132740 @default.
- W3201749743 cites W2045475405 @default.
- W3201749743 cites W2056249595 @default.
- W3201749743 cites W2093654081 @default.
- W3201749743 cites W2108373071 @default.
- W3201749743 cites W2116171543 @default.
- W3201749743 cites W2142943268 @default.
- W3201749743 cites W2149992805 @default.
- W3201749743 cites W2150539666 @default.
- W3201749743 cites W2169579205 @default.
- W3201749743 cites W2172065556 @default.
- W3201749743 cites W2265134611 @default.
- W3201749743 cites W2398298261 @default.
- W3201749743 cites W2508697147 @default.
- W3201749743 cites W2548694234 @default.
- W3201749743 cites W2569050105 @default.
- W3201749743 cites W2583070206 @default.
- W3201749743 cites W2589417329 @default.
- W3201749743 cites W2611873621 @default.
- W3201749743 cites W2626153771 @default.
- W3201749743 cites W2767731416 @default.
- W3201749743 cites W2773804840 @default.
- W3201749743 cites W2775161773 @default.
- W3201749743 cites W2791853504 @default.
- W3201749743 cites W2800187318 @default.
- W3201749743 cites W2802060782 @default.
- W3201749743 cites W2805135934 @default.
- W3201749743 cites W2807110328 @default.
- W3201749743 cites W2810715813 @default.
- W3201749743 cites W2864786814 @default.
- W3201749743 cites W2885806940 @default.
- W3201749743 cites W2887418427 @default.
- W3201749743 cites W2890955229 @default.
- W3201749743 cites W2893124025 @default.
- W3201749743 cites W2893691711 @default.
- W3201749743 cites W2897323740 @default.
- W3201749743 cites W2901262057 @default.
- W3201749743 cites W2903062212 @default.
- W3201749743 cites W2903484859 @default.
- W3201749743 cites W2903565415 @default.
- W3201749743 cites W2906950793 @default.
- W3201749743 cites W2913136103 @default.
- W3201749743 cites W2918120897 @default.
- W3201749743 cites W2923654788 @default.
- W3201749743 cites W2955975697 @default.
- W3201749743 cites W2969348242 @default.
- W3201749743 cites W2971477701 @default.
- W3201749743 cites W2972280750 @default.
- W3201749743 cites W2974276379 @default.
- W3201749743 cites W2980601614 @default.
- W3201749743 cites W2989809912 @default.
- W3201749743 cites W2994801226 @default.
- W3201749743 cites W2998345757 @default.
- W3201749743 cites W3000883312 @default.
- W3201749743 cites W3003850371 @default.
- W3201749743 cites W3004611567 @default.
- W3201749743 cites W3007769221 @default.
- W3201749743 cites W3017464623 @default.
- W3201749743 cites W3023646441 @default.
- W3201749743 cites W3024103680 @default.
- W3201749743 cites W3032567649 @default.
- W3201749743 cites W3038790873 @default.
- W3201749743 cites W3041276616 @default.
- W3201749743 cites W3048028213 @default.
- W3201749743 cites W3080714131 @default.
- W3201749743 cites W3091048385 @default.
- W3201749743 cites W3092444112 @default.
- W3201749743 cites W3095686188 @default.
- W3201749743 cites W3097015693 @default.
- W3201749743 cites W3105835660 @default.
- W3201749743 cites W3108211592 @default.
- W3201749743 cites W3113171896 @default.
- W3201749743 cites W3120017373 @default.
- W3201749743 cites W3132062361 @default.
- W3201749743 cites W3132281209 @default.
- W3201749743 cites W3135011427 @default.
- W3201749743 cites W3138655578 @default.
- W3201749743 cites W3160669634 @default.
- W3201749743 cites W576867606 @default.
- W3201749743 doi "https://doi.org/10.3389/fimmu.2021.744823" @default.
- W3201749743 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/8526896" @default.
- W3201749743 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/34691052" @default.
- W3201749743 hasPublicationYear "2021" @default.
- W3201749743 type Work @default.
- W3201749743 sameAs 3201749743 @default.