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• W3201844425 abstract "IntroductionCatheter-based radiofrequency ablation is the most common treatment option to prevent recurrent implantable cardioverter-defibrillator (ICD) therapies in patients with ventricular tachycardia (VT).1Cronin E.M. Bogun F.M. Maury P. et al.2019 HRS/EHRA/APHRS/LAHRS expert consensus statement on catheter ablation of ventricular arrhythmias.Heart Rhythm. 2020; 17: e2-e154Abstract Full Text Full Text PDF PubMed Scopus (105) Google Scholar However, in patients with nonischemic cardiomyopathy, the radiofrequency ablation is considered ineffective owing to nonuniformity in the distribution of scar.2Anter E. Hutchinson M.D. Deo R. et al.Surgical ablation of refractory ventricular tachycardia in patients with nonischemic cardiomyopathy.Circ Arrhythm Electrophysiol. 2011; 4: 494-500Crossref PubMed Scopus (54) Google Scholar An epicardial scar may require ablation via the coronary venous system or using the pericardial approach.3Al-Khatib S.M. Stevenson W.G. Ackerman M.J. et al.2017 AHA/ACC/HRS Guideline for Management of Patients With Ventricular Arrhythmias and the Prevention of Sudden Cardiac Death: A Report of the American College of Cardiology/American Heart Association Task Force on Clinical Practice Guidelines and the Heart Rhythm Society.J Am Coll Cardiol. 2018; 72: e91-e220Crossref PubMed Scopus (456) Google Scholar In some patients with left ventricular summit VT, owing to proximity of proximal coronary vessels, inability to deliver adequate lesions within the anterior interventricular vein (even with impedance limiter turned off), and inaccessible pericardial space owing to adhesions, a surgical approach with epicardial mapping may have to be done. We present a patient with nonischemic dilated cardiomyopathy, recurrent VT, and ICD therapies, who after failure of percutaneous approaches underwent elective open sternotomy, mapping using a traditional electrophysiology catheter on a beating heart, and subsequent cryoablation. Open surgical epicardial entrainment mapping and cryoablation of summit VT has not been previously reported.Case reportA 63-year-old patient with a history of recurrent VT (Figure 1), nonischemic cardiomyopathy, and chronic systolic heart failure with recurrent ICD therapies was referred for ablation. Comorbidities included deep vein thrombosis, history of pulmonary embolism on anticoagulation, morbid obesity, sleep apnea, and anxiety from recurrent ICD therapies.She had failed medical therapy with amiodarone and mexiletine and had previously undergone 2 VT ablation procedures including endocardial and attempted epicardial approaches. The coronary sinus approach was not feasible owing to the completely occluded great cardiac vein and anterior interventricular vein.4Roberts-Thomson K.C. Steven D. Seiler J. et al.Coronary artery injury due to catheter ablation in adults: presentations and outcomes.Circulation. 2009; 120: 1465-1473Crossref PubMed Scopus (125) Google Scholar Percutaneous pericardial approach was not feasible owing to extensive pericardial adhesions.5Santangeli P. Marchlinski F.E. Zado E.S. et al.Percutaneous epicardial ablation of ventricular arrhythmias arising from the left ventricular summit: outcomes and electrocardiogram correlates of success.Circ Arrhythm Electrophysiol. 2015; 8: 337-343Crossref PubMed Scopus (104) Google Scholar Owing to recurrent VT, she was taken to the electrophysiology lab for another epicardial VT ablation via open sternotomy.Median sternotomy was performed by a cardiothoracic team. ICD was used to induce clinical VT with a ventricular burst at 340 ms. During induced VT (identical morphology to clinical VT), the patient was hemodynamically stable; epicardial activation and entrainment mapping were done to identify critical isthmus using a PentaRay catheter (Boston Scientific, Marlborough, MA; Figure 2A ). Entrainment mapping (Figure 3; stim-QRS/TCL = 30%, Stim-QRS = electrogram-QRS) was identified at the border between LV summit and anterolateral epicardial wall. Limited activation and voltage mapping were performed using the 3-dimensional CARTO mapping system (Biosense Webster, Diamond Bar, CA) (Supplemental Figure 1) but owing to interference from the metal retractor, the images were rendered only at a certain distance from the retractor. Besides, concealed entrainment finding with diastolic electrograms reduced the need for comprehensive mapping. A 120-second cryoablation at this location was performed (Figure 2B). Three insurance lesions of similar duration were delivered to adjacent LV summit and bordering anterolateral region.Figure 2A: PentaRay catheter (Boston Scientific, Marborough, MA) on the anterolateral wall. LAA = left atrial appendage; PA = pulmonary artery; RVOT = right ventricular outflow tract. B: Surgical cryoprobe performing cryoablation encompassing the central isthmus.View Large Image Figure ViewerDownload Hi-res image Download (PPT)Figure 3Concealed entrainment using the PentaRay catheter (Boston Scientific, Marborough, MA) from left ventricular summit and bordering anterolateral wall, revealing capture at the central isthmus. Stim to electrogram/TCL at 30% is within central isthmus, closer to exit site.View Large Image Figure ViewerDownload Hi-res image Download (PPT)Subsequent programmed ventricular electrical stimulation did not induce any further VT.The patient recovered in the hospital as per standard open heart surgery protocol. She was assessed during regular clinic visits by patient interview, 12-lead electrocardiogram, and device interrogation. At 6-month follow-up, ICD interrogation confirmed that the patient is free of any significant ventricular arrhythmias.DiscussionNonischemic dilated cardiomyopathy is frequently associated with ventricular arrhythmia of epicardial origin. Access to these areas can generally be accomplished using coronary venous branches or a percutaneous epicardial approach. In this instance, access to the coronary venous system and percutaneous pericardial approach failed.3Al-Khatib S.M. Stevenson W.G. Ackerman M.J. et al.2017 AHA/ACC/HRS Guideline for Management of Patients With Ventricular Arrhythmias and the Prevention of Sudden Cardiac Death: A Report of the American College of Cardiology/American Heart Association Task Force on Clinical Practice Guidelines and the Heart Rhythm Society.J Am Coll Cardiol. 2018; 72: e91-e220Crossref PubMed Scopus (456) Google ScholarThe subsequent decision involved a team discussion comprising the patient, cardiothoracic team, and cardiovascular/electrophysiology team members. A minimally invasive surgery vs median sternotomy approaches was discussed. Owing to morbid obesity, underlying pulmonary issues, and dense pericardial adhesions, open sternotomy was preferred over endoscopic, robotic ablation.6Mulpuru S.K. Feld G.K. Madani M. Sawhney N.S. A novel, minimally-invasive surgical approach for ablation of ventricular tachycardia originating near the proximal left anterior descending coronary artery.Circ Arrhythm Electrophysiol. 2012; 5: e95-e97Crossref PubMed Scopus (23) Google Scholar The patient agreed to undergo the procedure after being an active member of the group discussion.The advantage of median sternotomy is that it allows total exposure of nearly all of the ventricular myocardium through the mediastinum.7Michowitz Y. Mathuria N. Tung R. et al.Hybrid procedures for epicardial catheter ablation of ventricular tachycardia: value of surgical access.Heart Rhythm. 2010; 7: 1635-1643Abstract Full Text Full Text PDF PubMed Scopus (61) Google Scholar,8Li A. Hayase J. Do D. et al.Hybrid surgical vs percutaneous access epicardial ventricular tachycardia ablation.Heart Rhythm. 2018; 15: 512-519Abstract Full Text Full Text PDF PubMed Scopus (20) Google Scholar Additionally, complete exposure of the heart allows for vascular control in case of an injury and provides access for cardiopulmonary bypass in case of an emergency. Although irrigated radiofrequency ablation was available, cryoablation was considered safe by the team members owing to proximity of the scar to both the left anterior descending and circumflex coronary arteries in this position, and radiofrequency would be used as a bail-out strategy, in case of persistent inducibility.9Aziz Z. Moss J.D. Jabbarzadeh M. Hellstrom J. Balkhy H. Tung R. Totally endoscopic robotic epicardial ablation of refractory left ventricular summit arrhythmia: first-in-man.Heart Rhythm. 2017; 14: 135-138Abstract Full Text Full Text PDF PubMed Scopus (23) Google Scholar The cryoablation technique also provides enhanced catheter stabilization, which reduces damage to adjacent tissues.10Aoyama H. Nakagawa H. Pitha J.V. et al.Comparison of cryothermia and radiofrequency current in safety and efficacy of catheter ablation within the canine coronary sinus close to the left circumflex coronary artery.J Cardiovasc Electrophysiol. 2005; 16: 1218-1226Crossref PubMed Scopus (101) Google Scholar,11Di Biase L. Al-Ahamad A. Santangeli P. et al.Safety and outcomes of cryoablation for ventricular tachyarrhythmias: results from a multicenter experience.Heart Rhythm. 2011; 8: 968-974Abstract Full Text Full Text PDF PubMed Scopus (51) Google ScholarThe PentaRay catheter used for entrainment mapping has a small electrode size and close interelectrode spacing, which helps in better mapping resolution.12Maagh P. Christoph A. Dopp H. Mueller M.S. Plehn G. Meissner A. High-density mapping in ventricular tachycardia ablation: a PentaRay((R)) study.Cardiol Res. 2017; 8: 293-303Crossref PubMed Google Scholar,13Acosta J. Penela D. Andreu D. et al.Multielectrode vs. point-by-point mapping for ventricular tachycardia substrate ablation: a randomized study.Europace. 2018; 20: 512-519Crossref PubMed Scopus (36) Google ScholarConclusionOpen sternotomy with epicardial VT mapping using conventional electrophysiology catheter carries the major advantage of direct anatomical visualization and enhanced catheter stability. Therefore, hybrid VT ablation is effective in patients with multiple failed ablation attempts and pericardial adhesions. IntroductionCatheter-based radiofrequency ablation is the most common treatment option to prevent recurrent implantable cardioverter-defibrillator (ICD) therapies in patients with ventricular tachycardia (VT).1Cronin E.M. Bogun F.M. Maury P. et al.2019 HRS/EHRA/APHRS/LAHRS expert consensus statement on catheter ablation of ventricular arrhythmias.Heart Rhythm. 2020; 17: e2-e154Abstract Full Text Full Text PDF PubMed Scopus (105) Google Scholar However, in patients with nonischemic cardiomyopathy, the radiofrequency ablation is considered ineffective owing to nonuniformity in the distribution of scar.2Anter E. Hutchinson M.D. Deo R. et al.Surgical ablation of refractory ventricular tachycardia in patients with nonischemic cardiomyopathy.Circ Arrhythm Electrophysiol. 2011; 4: 494-500Crossref PubMed Scopus (54) Google Scholar An epicardial scar may require ablation via the coronary venous system or using the pericardial approach.3Al-Khatib S.M. Stevenson W.G. Ackerman M.J. et al.2017 AHA/ACC/HRS Guideline for Management of Patients With Ventricular Arrhythmias and the Prevention of Sudden Cardiac Death: A Report of the American College of Cardiology/American Heart Association Task Force on Clinical Practice Guidelines and the Heart Rhythm Society.J Am Coll Cardiol. 2018; 72: e91-e220Crossref PubMed Scopus (456) Google Scholar In some patients with left ventricular summit VT, owing to proximity of proximal coronary vessels, inability to deliver adequate lesions within the anterior interventricular vein (even with impedance limiter turned off), and inaccessible pericardial space owing to adhesions, a surgical approach with epicardial mapping may have to be done. We present a patient with nonischemic dilated cardiomyopathy, recurrent VT, and ICD therapies, who after failure of percutaneous approaches underwent elective open sternotomy, mapping using a traditional electrophysiology catheter on a beating heart, and subsequent cryoablation. Open surgical epicardial entrainment mapping and cryoablation of summit VT has not been previously reported. Catheter-based radiofrequency ablation is the most common treatment option to prevent recurrent implantable cardioverter-defibrillator (ICD) therapies in patients with ventricular tachycardia (VT).1Cronin E.M. Bogun F.M. Maury P. et al.2019 HRS/EHRA/APHRS/LAHRS expert consensus statement on catheter ablation of ventricular arrhythmias.Heart Rhythm. 2020; 17: e2-e154Abstract Full Text Full Text PDF PubMed Scopus (105) Google Scholar However, in patients with nonischemic cardiomyopathy, the radiofrequency ablation is considered ineffective owing to nonuniformity in the distribution of scar.2Anter E. Hutchinson M.D. Deo R. et al.Surgical ablation of refractory ventricular tachycardia in patients with nonischemic cardiomyopathy.Circ Arrhythm Electrophysiol. 2011; 4: 494-500Crossref PubMed Scopus (54) Google Scholar An epicardial scar may require ablation via the coronary venous system or using the pericardial approach.3Al-Khatib S.M. Stevenson W.G. Ackerman M.J. et al.2017 AHA/ACC/HRS Guideline for Management of Patients With Ventricular Arrhythmias and the Prevention of Sudden Cardiac Death: A Report of the American College of Cardiology/American Heart Association Task Force on Clinical Practice Guidelines and the Heart Rhythm Society.J Am Coll Cardiol. 2018; 72: e91-e220Crossref PubMed Scopus (456) Google Scholar In some patients with left ventricular summit VT, owing to proximity of proximal coronary vessels, inability to deliver adequate lesions within the anterior interventricular vein (even with impedance limiter turned off), and inaccessible pericardial space owing to adhesions, a surgical approach with epicardial mapping may have to be done. We present a patient with nonischemic dilated cardiomyopathy, recurrent VT, and ICD therapies, who after failure of percutaneous approaches underwent elective open sternotomy, mapping using a traditional electrophysiology catheter on a beating heart, and subsequent cryoablation. Open surgical epicardial entrainment mapping and cryoablation of summit VT has not been previously reported. Case reportA 63-year-old patient with a history of recurrent VT (Figure 1), nonischemic cardiomyopathy, and chronic systolic heart failure with recurrent ICD therapies was referred for ablation. Comorbidities included deep vein thrombosis, history of pulmonary embolism on anticoagulation, morbid obesity, sleep apnea, and anxiety from recurrent ICD therapies.She had failed medical therapy with amiodarone and mexiletine and had previously undergone 2 VT ablation procedures including endocardial and attempted epicardial approaches. The coronary sinus approach was not feasible owing to the completely occluded great cardiac vein and anterior interventricular vein.4Roberts-Thomson K.C. Steven D. Seiler J. et al.Coronary artery injury due to catheter ablation in adults: presentations and outcomes.Circulation. 2009; 120: 1465-1473Crossref PubMed Scopus (125) Google Scholar Percutaneous pericardial approach was not feasible owing to extensive pericardial adhesions.5Santangeli P. Marchlinski F.E. Zado E.S. et al.Percutaneous epicardial ablation of ventricular arrhythmias arising from the left ventricular summit: outcomes and electrocardiogram correlates of success.Circ Arrhythm Electrophysiol. 2015; 8: 337-343Crossref PubMed Scopus (104) Google Scholar Owing to recurrent VT, she was taken to the electrophysiology lab for another epicardial VT ablation via open sternotomy.Median sternotomy was performed by a cardiothoracic team. ICD was used to induce clinical VT with a ventricular burst at 340 ms. During induced VT (identical morphology to clinical VT), the patient was hemodynamically stable; epicardial activation and entrainment mapping were done to identify critical isthmus using a PentaRay catheter (Boston Scientific, Marlborough, MA; Figure 2A ). Entrainment mapping (Figure 3; stim-QRS/TCL = 30%, Stim-QRS = electrogram-QRS) was identified at the border between LV summit and anterolateral epicardial wall. Limited activation and voltage mapping were performed using the 3-dimensional CARTO mapping system (Biosense Webster, Diamond Bar, CA) (Supplemental Figure 1) but owing to interference from the metal retractor, the images were rendered only at a certain distance from the retractor. Besides, concealed entrainment finding with diastolic electrograms reduced the need for comprehensive mapping. A 120-second cryoablation at this location was performed (Figure 2B). Three insurance lesions of similar duration were delivered to adjacent LV summit and bordering anterolateral region.Figure 3Concealed entrainment using the PentaRay catheter (Boston Scientific, Marborough, MA) from left ventricular summit and bordering anterolateral wall, revealing capture at the central isthmus. Stim to electrogram/TCL at 30% is within central isthmus, closer to exit site.View Large Image Figure ViewerDownload Hi-res image Download (PPT)Subsequent programmed ventricular electrical stimulation did not induce any further VT.The patient recovered in the hospital as per standard open heart surgery protocol. She was assessed during regular clinic visits by patient interview, 12-lead electrocardiogram, and device interrogation. At 6-month follow-up, ICD interrogation confirmed that the patient is free of any significant ventricular arrhythmias. A 63-year-old patient with a history of recurrent VT (Figure 1), nonischemic cardiomyopathy, and chronic systolic heart failure with recurrent ICD therapies was referred for ablation. Comorbidities included deep vein thrombosis, history of pulmonary embolism on anticoagulation, morbid obesity, sleep apnea, and anxiety from recurrent ICD therapies. She had failed medical therapy with amiodarone and mexiletine and had previously undergone 2 VT ablation procedures including endocardial and attempted epicardial approaches. The coronary sinus approach was not feasible owing to the completely occluded great cardiac vein and anterior interventricular vein.4Roberts-Thomson K.C. Steven D. Seiler J. et al.Coronary artery injury due to catheter ablation in adults: presentations and outcomes.Circulation. 2009; 120: 1465-1473Crossref PubMed Scopus (125) Google Scholar Percutaneous pericardial approach was not feasible owing to extensive pericardial adhesions.5Santangeli P. Marchlinski F.E. Zado E.S. et al.Percutaneous epicardial ablation of ventricular arrhythmias arising from the left ventricular summit: outcomes and electrocardiogram correlates of success.Circ Arrhythm Electrophysiol. 2015; 8: 337-343Crossref PubMed Scopus (104) Google Scholar Owing to recurrent VT, she was taken to the electrophysiology lab for another epicardial VT ablation via open sternotomy. Median sternotomy was performed by a cardiothoracic team. ICD was used to induce clinical VT with a ventricular burst at 340 ms. During induced VT (identical morphology to clinical VT), the patient was hemodynamically stable; epicardial activation and entrainment mapping were done to identify critical isthmus using a PentaRay catheter (Boston Scientific, Marlborough, MA; Figure 2A ). Entrainment mapping (Figure 3; stim-QRS/TCL = 30%, Stim-QRS = electrogram-QRS) was identified at the border between LV summit and anterolateral epicardial wall. Limited activation and voltage mapping were performed using the 3-dimensional CARTO mapping system (Biosense Webster, Diamond Bar, CA) (Supplemental Figure 1) but owing to interference from the metal retractor, the images were rendered only at a certain distance from the retractor. Besides, concealed entrainment finding with diastolic electrograms reduced the need for comprehensive mapping. A 120-second cryoablation at this location was performed (Figure 2B). Three insurance lesions of similar duration were delivered to adjacent LV summit and bordering anterolateral region. Subsequent programmed ventricular electrical stimulation did not induce any further VT. The patient recovered in the hospital as per standard open heart surgery protocol. She was assessed during regular clinic visits by patient interview, 12-lead electrocardiogram, and device interrogation. At 6-month follow-up, ICD interrogation confirmed that the patient is free of any significant ventricular arrhythmias. DiscussionNonischemic dilated cardiomyopathy is frequently associated with ventricular arrhythmia of epicardial origin. Access to these areas can generally be accomplished using coronary venous branches or a percutaneous epicardial approach. In this instance, access to the coronary venous system and percutaneous pericardial approach failed.3Al-Khatib S.M. Stevenson W.G. Ackerman M.J. et al.2017 AHA/ACC/HRS Guideline for Management of Patients With Ventricular Arrhythmias and the Prevention of Sudden Cardiac Death: A Report of the American College of Cardiology/American Heart Association Task Force on Clinical Practice Guidelines and the Heart Rhythm Society.J Am Coll Cardiol. 2018; 72: e91-e220Crossref PubMed Scopus (456) Google ScholarThe subsequent decision involved a team discussion comprising the patient, cardiothoracic team, and cardiovascular/electrophysiology team members. A minimally invasive surgery vs median sternotomy approaches was discussed. Owing to morbid obesity, underlying pulmonary issues, and dense pericardial adhesions, open sternotomy was preferred over endoscopic, robotic ablation.6Mulpuru S.K. Feld G.K. Madani M. Sawhney N.S. A novel, minimally-invasive surgical approach for ablation of ventricular tachycardia originating near the proximal left anterior descending coronary artery.Circ Arrhythm Electrophysiol. 2012; 5: e95-e97Crossref PubMed Scopus (23) Google Scholar The patient agreed to undergo the procedure after being an active member of the group discussion.The advantage of median sternotomy is that it allows total exposure of nearly all of the ventricular myocardium through the mediastinum.7Michowitz Y. Mathuria N. Tung R. et al.Hybrid procedures for epicardial catheter ablation of ventricular tachycardia: value of surgical access.Heart Rhythm. 2010; 7: 1635-1643Abstract Full Text Full Text PDF PubMed Scopus (61) Google Scholar,8Li A. Hayase J. Do D. et al.Hybrid surgical vs percutaneous access epicardial ventricular tachycardia ablation.Heart Rhythm. 2018; 15: 512-519Abstract Full Text Full Text PDF PubMed Scopus (20) Google Scholar Additionally, complete exposure of the heart allows for vascular control in case of an injury and provides access for cardiopulmonary bypass in case of an emergency. Although irrigated radiofrequency ablation was available, cryoablation was considered safe by the team members owing to proximity of the scar to both the left anterior descending and circumflex coronary arteries in this position, and radiofrequency would be used as a bail-out strategy, in case of persistent inducibility.9Aziz Z. Moss J.D. Jabbarzadeh M. Hellstrom J. Balkhy H. Tung R. Totally endoscopic robotic epicardial ablation of refractory left ventricular summit arrhythmia: first-in-man.Heart Rhythm. 2017; 14: 135-138Abstract Full Text Full Text PDF PubMed Scopus (23) Google Scholar The cryoablation technique also provides enhanced catheter stabilization, which reduces damage to adjacent tissues.10Aoyama H. Nakagawa H. Pitha J.V. et al.Comparison of cryothermia and radiofrequency current in safety and efficacy of catheter ablation within the canine coronary sinus close to the left circumflex coronary artery.J Cardiovasc Electrophysiol. 2005; 16: 1218-1226Crossref PubMed Scopus (101) Google Scholar,11Di Biase L. Al-Ahamad A. Santangeli P. et al.Safety and outcomes of cryoablation for ventricular tachyarrhythmias: results from a multicenter experience.Heart Rhythm. 2011; 8: 968-974Abstract Full Text Full Text PDF PubMed Scopus (51) Google ScholarThe PentaRay catheter used for entrainment mapping has a small electrode size and close interelectrode spacing, which helps in better mapping resolution.12Maagh P. Christoph A. Dopp H. Mueller M.S. Plehn G. Meissner A. High-density mapping in ventricular tachycardia ablation: a PentaRay((R)) study.Cardiol Res. 2017; 8: 293-303Crossref PubMed Google Scholar,13Acosta J. Penela D. Andreu D. et al.Multielectrode vs. point-by-point mapping for ventricular tachycardia substrate ablation: a randomized study.Europace. 2018; 20: 512-519Crossref PubMed Scopus (36) Google Scholar Nonischemic dilated cardiomyopathy is frequently associated with ventricular arrhythmia of epicardial origin. Access to these areas can generally be accomplished using coronary venous branches or a percutaneous epicardial approach. In this instance, access to the coronary venous system and percutaneous pericardial approach failed.3Al-Khatib S.M. Stevenson W.G. Ackerman M.J. et al.2017 AHA/ACC/HRS Guideline for Management of Patients With Ventricular Arrhythmias and the Prevention of Sudden Cardiac Death: A Report of the American College of Cardiology/American Heart Association Task Force on Clinical Practice Guidelines and the Heart Rhythm Society.J Am Coll Cardiol. 2018; 72: e91-e220Crossref PubMed Scopus (456) Google Scholar The subsequent decision involved a team discussion comprising the patient, cardiothoracic team, and cardiovascular/electrophysiology team members. A minimally invasive surgery vs median sternotomy approaches was discussed. Owing to morbid obesity, underlying pulmonary issues, and dense pericardial adhesions, open sternotomy was preferred over endoscopic, robotic ablation.6Mulpuru S.K. Feld G.K. Madani M. Sawhney N.S. A novel, minimally-invasive surgical approach for ablation of ventricular tachycardia originating near the proximal left anterior descending coronary artery.Circ Arrhythm Electrophysiol. 2012; 5: e95-e97Crossref PubMed Scopus (23) Google Scholar The patient agreed to undergo the procedure after being an active member of the group discussion. The advantage of median sternotomy is that it allows total exposure of nearly all of the ventricular myocardium through the mediastinum.7Michowitz Y. Mathuria N. Tung R. et al.Hybrid procedures for epicardial catheter ablation of ventricular tachycardia: value of surgical access.Heart Rhythm. 2010; 7: 1635-1643Abstract Full Text Full Text PDF PubMed Scopus (61) Google Scholar,8Li A. Hayase J. Do D. et al.Hybrid surgical vs percutaneous access epicardial ventricular tachycardia ablation.Heart Rhythm. 2018; 15: 512-519Abstract Full Text Full Text PDF PubMed Scopus (20) Google Scholar Additionally, complete exposure of the heart allows for vascular control in case of an injury and provides access for cardiopulmonary bypass in case of an emergency. Although irrigated radiofrequency ablation was available, cryoablation was considered safe by the team members owing to proximity of the scar to both the left anterior descending and circumflex coronary arteries in this position, and radiofrequency would be used as a bail-out strategy, in case of persistent inducibility.9Aziz Z. Moss J.D. Jabbarzadeh M. Hellstrom J. Balkhy H. Tung R. Totally endoscopic robotic epicardial ablation of refractory left ventricular summit arrhythmia: first-in-man.Heart Rhythm. 2017; 14: 135-138Abstract Full Text Full Text PDF PubMed Scopus (23) Google Scholar The cryoablation technique also provides enhanced catheter stabilization, which reduces damage to adjacent tissues.10Aoyama H. Nakagawa H. Pitha J.V. et al.Comparison of cryothermia and radiofrequency current in safety and efficacy of catheter ablation within the canine coronary sinus close to the left circumflex coronary artery.J Cardiovasc Electrophysiol. 2005; 16: 1218-1226Crossref PubMed Scopus (101) Google Scholar,11Di Biase L. Al-Ahamad A. Santangeli P. et al.Safety and outcomes of cryoablation for ventricular tachyarrhythmias: results from a multicenter experience.Heart Rhythm. 2011; 8: 968-974Abstract Full Text Full Text PDF PubMed Scopus (51) Google Scholar The PentaRay catheter used for entrainment mapping has a small electrode size and close interelectrode spacing, which helps in better mapping resolution.12Maagh P. Christoph A. Dopp H. Mueller M.S. Plehn G. Meissner A. High-density mapping in ventricular tachycardia ablation: a PentaRay((R)) study.Cardiol Res. 2017; 8: 293-303Crossref PubMed Google Scholar,13Acosta J. Penela D. Andreu D. et al.Multielectrode vs. point-by-point mapping for ventricular tachycardia substrate ablation: a randomized study.Europace. 2018; 20: 512-519Crossref PubMed Scopus (36) Google Scholar ConclusionOpen sternotomy with epicardial VT mapping using conventional electrophysiology catheter carries the major advantage of direct anatomical visualization and enhanced catheter stability. Therefore, hybrid VT ablation is effective in patients with multiple failed ablation attempts and pericardial adhesions. Open sternotomy with epicardial VT mapping using conventional electrophysiology catheter carries the major advantage of direct anatomical visualization and enhanced catheter stability. Therefore, hybrid VT ablation is effective in patients with multiple failed ablation attempts and pericardial adhesions." @default.
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• W3201844425 title "Left ventricular summit ablation through open sternotomy with hybrid utilization of standard electrophysiology catheters and maneuvers" @default.
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