Matches in SemOpenAlex for { <https://semopenalex.org/work/W3201907975> ?p ?o ?g. }
Showing items 1 to 68 of
68
with 100 items per page.
- W3201907975 endingPage "21" @default.
- W3201907975 startingPage "18" @default.
- W3201907975 abstract "Glutamic acid decarboxylase (GAD) is considered as target antigen in pancreatic beta cell autoimmunity. Two isoforms of GAD (islet and brain GAD) were detected recently. In circulation of approximately 80 % of recently detected patients with insulin-dependent diabetes mellitus (IDDM) autoantibodies to brain GAD (bGAD) have been demonstrated. To detect autoantibodies to bGAD blood sera of 48 children aged 1 to 14, 36 of these with newly diagnosed IDDM, 2 with impaired glucose tolerance (IGT), 10 healthy controls, were tested. Indirect immunofluorescent staining of rat cerebellum cryoslices was carried out. The results were assessed using fluorescent microscopy and processed by statistical methods. Autoantibodies to bGAD were found in 30 out of 36 patients with IDDM: 83,3±12,4 % (p=95%), in 1 with IGT, and in none of controls. The fact that all controls were anti- body-negative proves a high specificity of this immunological marker of IDDM. Family history or a younger age by the moment of diabetes onset were conducive to a higher prevalence of autoantibodies to GAD, each of these factors being unrelated to the other." @default.
- W3201907975 created "2021-10-11" @default.
- W3201907975 creator A5003377649 @default.
- W3201907975 creator A5022058884 @default.
- W3201907975 creator A5022075559 @default.
- W3201907975 creator A5024582221 @default.
- W3201907975 creator A5025455953 @default.
- W3201907975 creator A5030271532 @default.
- W3201907975 creator A5046191937 @default.
- W3201907975 creator A5046472005 @default.
- W3201907975 date "1994-04-15" @default.
- W3201907975 modified "2023-09-27" @default.
- W3201907975 title "Аутоантитела к глутаматдекарбоксилазе у детей с впервые выявленным инсулинзависимым сахарным диабетом" @default.
- W3201907975 doi "https://doi.org/10.14341/probl11546" @default.
- W3201907975 hasPublicationYear "1994" @default.
- W3201907975 type Work @default.
- W3201907975 sameAs 3201907975 @default.
- W3201907975 citedByCount "0" @default.
- W3201907975 crossrefType "journal-article" @default.
- W3201907975 hasAuthorship W3201907975A5003377649 @default.
- W3201907975 hasAuthorship W3201907975A5022058884 @default.
- W3201907975 hasAuthorship W3201907975A5022075559 @default.
- W3201907975 hasAuthorship W3201907975A5024582221 @default.
- W3201907975 hasAuthorship W3201907975A5025455953 @default.
- W3201907975 hasAuthorship W3201907975A5030271532 @default.
- W3201907975 hasAuthorship W3201907975A5046191937 @default.
- W3201907975 hasAuthorship W3201907975A5046472005 @default.
- W3201907975 hasConcept C126322002 @default.
- W3201907975 hasConcept C134018914 @default.
- W3201907975 hasConcept C159654299 @default.
- W3201907975 hasConcept C163764329 @default.
- W3201907975 hasConcept C165220095 @default.
- W3201907975 hasConcept C181199279 @default.
- W3201907975 hasConcept C203014093 @default.
- W3201907975 hasConcept C2777180221 @default.
- W3201907975 hasConcept C2780130043 @default.
- W3201907975 hasConcept C2780609358 @default.
- W3201907975 hasConcept C55493867 @default.
- W3201907975 hasConcept C555293320 @default.
- W3201907975 hasConcept C71924100 @default.
- W3201907975 hasConcept C86803240 @default.
- W3201907975 hasConcept C9497952 @default.
- W3201907975 hasConceptScore W3201907975C126322002 @default.
- W3201907975 hasConceptScore W3201907975C134018914 @default.
- W3201907975 hasConceptScore W3201907975C159654299 @default.
- W3201907975 hasConceptScore W3201907975C163764329 @default.
- W3201907975 hasConceptScore W3201907975C165220095 @default.
- W3201907975 hasConceptScore W3201907975C181199279 @default.
- W3201907975 hasConceptScore W3201907975C203014093 @default.
- W3201907975 hasConceptScore W3201907975C2777180221 @default.
- W3201907975 hasConceptScore W3201907975C2780130043 @default.
- W3201907975 hasConceptScore W3201907975C2780609358 @default.
- W3201907975 hasConceptScore W3201907975C55493867 @default.
- W3201907975 hasConceptScore W3201907975C555293320 @default.
- W3201907975 hasConceptScore W3201907975C71924100 @default.
- W3201907975 hasConceptScore W3201907975C86803240 @default.
- W3201907975 hasConceptScore W3201907975C9497952 @default.
- W3201907975 hasIssue "2" @default.
- W3201907975 hasLocation W32019079751 @default.
- W3201907975 hasOpenAccess W3201907975 @default.
- W3201907975 hasPrimaryLocation W32019079751 @default.
- W3201907975 hasVolume "40" @default.
- W3201907975 isParatext "false" @default.
- W3201907975 isRetracted "false" @default.
- W3201907975 magId "3201907975" @default.
- W3201907975 workType "article" @default.