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- W3201951720 endingPage "1090" @default.
- W3201951720 startingPage "1077" @default.
- W3201951720 abstract "Soft tissue in the human body can be visualized by MRI with unprecedented sensitivity, contrast, and spatial resolution, and for this reason, MRI is the premier choice of diagnostic imaging technique for many pathologies. However, conventional MRI often lacks specificity in terms of differential diagnoses and provides little information on tissue function or metabolism. In vivo proton ( 1 H) MR spectroscopic imaging (MRSI) combines the tools for spatial localization and mapping that were developed for MRI with the techniques for biochemical analysis that are applied in solution-state NMR spectroscopy. This allows the noninvasive imaging of metabolism in patients without the need for an injection of exogenous tracers or contrast agents. Currently, most clinical applications of MRS are focused on the brain, especially for the evaluation of brain tumors. This chapter introduces the evolution of technology for MRSI of the brain, and in particular describes 3D proton spectroscopic MRI with whole-brain coverage, and its applications to patients with brain tumors. Unfortunately, to date, vendor-provided MRS technology for clinical use has lagged far behind the capabilities developed in research labs and is limited to either single-voxel or multivoxel localization with very limited spatial coverage and resolution. However, the developments required to reach the full potential of this technology are on the way." @default.
- W3201951720 created "2021-10-11" @default.
- W3201951720 creator A5053850518 @default.
- W3201951720 date "2021-01-01" @default.
- W3201951720 modified "2023-09-26" @default.
- W3201951720 title "Spectroscopic MRI for Brain Tumor Imaging" @default.
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