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- W3201992509 abstract "We present a completely label-free three-dimensional (3D) optical coherence tomography (OCT)-based tissue dynamics imaging method for visualization and quantification of the metabolic and necrotic activities of tumor spheroid. Our method is based on a custom 3D scanning protocol that is designed to capture volumetric tissue dynamics tomography images only in a few tens of seconds. The method was applied to the evaluation of a tumor spheroid. The time-course viability alteration and anti-cancer drug response of the spheroid were visualized qualitatively and analyzed quantitatively. The similarity between the OCT-based dynamics images and fluorescence microscope images was also demonstrated." @default.
- W3201992509 created "2021-10-11" @default.
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- W3201992509 date "2021-10-12" @default.
- W3201992509 modified "2023-10-10" @default.
- W3201992509 title "Three-dimensional dynamics optical coherence tomography for tumor spheroid evaluation" @default.
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- W3201992509 doi "https://doi.org/10.1364/boe.440444" @default.
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