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- W3202006112 abstract "Several classes of heparan sulfate proteoglycan (HSPG) core proteins and all HS biosynthetic/modifying enzymes are evolutionarily conserved from human to Drosophila melanogaster. This genetically tractable model offers highly sophisticated techniques to manipulate gene function in a spatially and temporally controlled manner. Thus, Drosophila genetics has been a powerful system to explore functions of HSPGs in vivo. In this chapter, we will introduce three genetic techniques available in Drosophila: TARGET (temporal and regional gene expression targeting), MARCM (mosaic analysis with a repressible cell marker), and FLP-Out." @default.
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- W3202006112 date "2021-10-10" @default.
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- W3202006112 title "Molecular Genetic Techniques for the Proteoglycan Functions in Drosophila" @default.
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- W3202006112 doi "https://doi.org/10.1007/978-1-0716-1398-6_32" @default.
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