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- W3202079238 abstract "Common urological cancers of the pelvis include bladder and prostate cancer, as well as rarer diseases such as penile cancer. This chapter focuses on adjuvant therapies used after radical surgical resection of prostate and bladder cancer, and provides an introduction to systemic therapies used in these diseases. Adjuvant radiation therapy can be considered in men who have high-risk pathological features in their prostatectomy specimen. The recommended approach for patients with muscle invasive bladder cancer is neoadjuvant cisplatin-based chemotherapy. Two large randomized control trials have demonstrated a survival advantage with the use of neoadjuvant chemotherapy. Numerous historical randomized clinical trials have explored the efficacy of adjuvant chemotherapy in locally advanced bladder cancer. These trials demonstrated feasibility but used suboptimal chemotherapy regimens and were underpowered. More trials evaluated contemporary chemotherapy regimens in the adjuvant setting in patients with locally advanced bladder cancer." @default.
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- W3202079238 date "2021-09-10" @default.
- W3202079238 modified "2023-09-24" @default.
- W3202079238 title "Adjuvant Therapy Options for Urological Neoplasms" @default.
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- W3202079238 doi "https://doi.org/10.1002/9781119518495.ch23" @default.
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