FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W3202130833> ?p ?o ?g. }

• W3202130833 endingPage "43" @default.
• W3202130833 startingPage "43" @default.
• W3202130833 abstract "Background and objective: Since the peritumoral inflammatory reaction is of considerable importance in the oncological prognosis of bladder cancer, the neutrophil-to-lymphocyte ratio (NLR) may be a very practical and accessible biomarker in non-muscle invasive bladder tumors. This study aims to analyze parameters of non-muscle invasive bladder tumors and to identify and validate potential tumor markers with a prognostic role in this condition. Material and methods: 463 patients diagnosed with non-muscle invasive urothelial tumors, between January 2016 and June 2020, hospitalized at the Urology Clinic in Târgu Mureș, after transurethral resection of bladder tumor (TURBT) were investigated. Inclusion criteria were: non-muscle invasive tumors (Ta, T1, CIS), neutrophil-to-lymphocyte ratio (NLR) determination 2 weeks prior to TURBT and complete follow-up of patients. NLR cut-off was set at 3. Results: 371 people diagnosed with non-muscle invasive bladder tumors met the inclusion criteria. The mean age of the included patients was 69.96 years (IQR 35–93). 297 (80.05%) were male and 74 (19.95%) were female. 64.95% pTa tumors, 31.26% pT1, 1.07% pTa + CIS, and 2.69% pT1 + CIS, respectively, were identified. Distribution according to Grade: 196 (52.8%) G2, 159 (42.88%) G3 and 16 (4.32%) CIS. 284 (76.5%) patients presented with a single tumor and 87 (23.35%) with multiple tumors; 295 (79.5%) had tumors larger than 3 cm and 76 (20.5%) smaller than 3 cm. 228 (61.4%) presented with recurrence after 3 months after surgery. Overall survival at 5 years was 80.06%. Advanced age at the time of diagnosis correlated with low survival, p = 0.004. The mortality rate was higher among men (20.54%) than among women (17.58%). Statistically, there was a positive relationship between the increased ratio of neutrophils and lymphocytes in people diagnosed with non-muscle invasive bladder cancer and increased mortality rate, p = 0.003. Conclusions: The overall survival of patients with non-muscle invasive bladder cancer was negatively influenced by the advanced age of the patients at the time of diagnosis. Increased preoperative NLR was associated with a higher mortality rate in patients with non-muscle invasive bladder cancers. This assay is an accessible, easy to performand useful biomarker in the prognosis of non-muscle invasive bladder tumors." @default.
• W3202130833 created "2021-10-11" @default.
• W3202130833 creator A5008502474 @default.
• W3202130833 creator A5027708301 @default.
• W3202130833 creator A5045230907 @default.
• W3202130833 creator A5047805535 @default.
• W3202130833 creator A5052048564 @default.
• W3202130833 creator A5076476146 @default.
• W3202130833 date "2021-09-26" @default.
• W3202130833 modified "2023-10-17" @default.
• W3202130833 title "Validation of the importance of neutrophil-to-lymphocyte ratio in non-muscle invasive bladder cancer" @default.
• W3202130833 doi "https://doi.org/10.31083/jomh.2021.128" @default.
• W3202130833 hasPublicationYear "2021" @default.
• W3202130833 type Work @default.
• W3202130833 sameAs 3202130833 @default.
• W3202130833 citedByCount "0" @default.
• W3202130833 crossrefType "journal-article" @default.
• W3202130833 hasAuthorship W3202130833A5008502474 @default.
• W3202130833 hasAuthorship W3202130833A5027708301 @default.
• W3202130833 hasAuthorship W3202130833A5045230907 @default.
• W3202130833 hasAuthorship W3202130833A5047805535 @default.
• W3202130833 hasAuthorship W3202130833A5052048564 @default.
• W3202130833 hasAuthorship W3202130833A5076476146 @default.
• W3202130833 hasBestOaLocation W32021308331 @default.
• W3202130833 hasConcept C121608353 @default.
• W3202130833 hasConcept C126322002 @default.
• W3202130833 hasConcept C126894567 @default.
• W3202130833 hasConcept C142724271 @default.
• W3202130833 hasConcept C2777761686 @default.
• W3202130833 hasConcept C2778963024 @default.
• W3202130833 hasConcept C2780352672 @default.
• W3202130833 hasConcept C2781197716 @default.
• W3202130833 hasConcept C55493867 @default.
• W3202130833 hasConcept C71924100 @default.
• W3202130833 hasConcept C86803240 @default.
• W3202130833 hasConcept C90924648 @default.
• W3202130833 hasConceptScore W3202130833C121608353 @default.
• W3202130833 hasConceptScore W3202130833C126322002 @default.
• W3202130833 hasConceptScore W3202130833C126894567 @default.
• W3202130833 hasConceptScore W3202130833C142724271 @default.
• W3202130833 hasConceptScore W3202130833C2777761686 @default.
• W3202130833 hasConceptScore W3202130833C2778963024 @default.
• W3202130833 hasConceptScore W3202130833C2780352672 @default.
• W3202130833 hasConceptScore W3202130833C2781197716 @default.
• W3202130833 hasConceptScore W3202130833C55493867 @default.
• W3202130833 hasConceptScore W3202130833C71924100 @default.
• W3202130833 hasConceptScore W3202130833C86803240 @default.
• W3202130833 hasConceptScore W3202130833C90924648 @default.
• W3202130833 hasIssue "2" @default.
• W3202130833 hasLocation W32021308331 @default.
• W3202130833 hasLocation W32021308332 @default.
• W3202130833 hasOpenAccess W3202130833 @default.
• W3202130833 hasPrimaryLocation W32021308331 @default.
• W3202130833 hasRelatedWork W2248406923 @default.
• W3202130833 hasRelatedWork W2791997666 @default.
• W3202130833 hasRelatedWork W2803784881 @default.
• W3202130833 hasRelatedWork W2899192203 @default.
• W3202130833 hasRelatedWork W2899557804 @default.
• W3202130833 hasRelatedWork W2905398573 @default.
• W3202130833 hasRelatedWork W3108957962 @default.
• W3202130833 hasRelatedWork W4320007947 @default.
• W3202130833 hasRelatedWork W4361014534 @default.
• W3202130833 hasRelatedWork W2118673085 @default.
• W3202130833 hasVolume "18" @default.
• W3202130833 isParatext "false" @default.
• W3202130833 isRetracted "false" @default.
• W3202130833 magId "3202130833" @default.
• W3202130833 workType "article" @default.