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- W3202272145 abstract "Histone lactylation and acetylation compete for epigenetic modification of lysines and mark the levels of lactates and acetyl-CoA. Whether pyruvate is committed to lactate or acetyl-CoA generation as the outlet of glycolysis determines cell fate towards malignancy or not. Taking control over the glycolytic switch as marked by lactylation suggests novel therapeutic opportunities against cancers." @default.
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- W3202272145 date "2022-02-01" @default.
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- W3202272145 title "Histone lactylation: epigenetic mark of glycolytic switch" @default.
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- W3202272145 doi "https://doi.org/10.1016/j.tig.2021.09.009" @default.
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