FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W3202398148> ?p ?o ?g. }

• W3202398148 endingPage "120016" @default.
• W3202398148 startingPage "120016" @default.
• W3202398148 abstract "The links between the two archetypical basal ganglia disorders, dystonia and parkinsonism, are manifold and stem from clinical observations, imaging studies, animal models and genetics. The combination of both, i.e. the syndrome of dystonia-parkinsonism, is not uncommonly seen in movement disorders clinics and has a myriad of different underlying aetiologies, upon which treatment and prognosis depend. Based on a comprehensive literature review, we delineate the clinical spectrum of disorders presenting with dystonia-parkinsonism. The clinical approach depends primarily on the age at onset, associated neurological or systemic symptoms and neuroimaging. The tempo of disease progression, and the response to L-dopa are further important clues to tailor diagnostic approaches that may encompass dopamine transporter imaging, CSF analysis and, last but not least, genetic testing. Later in life, sporadic neurodegenerative conditions are the most frequent cause, but the younger the patient, the more likely the cause is unravelled by the recent advances of molecular genetics that are focus of this review. Here, knowledge of the associated phenotypic spectrum is key to guide genetic testing and interpretation of test results. This article is part of the Special Issue Parkinsonism across the spectrum of movement disorders and beyond edited by Joseph Jankovic, Daniel D. Truong and Matteo Bologna." @default.
• W3202398148 created "2021-10-11" @default.
• W3202398148 creator A5002674323 @default.
• W3202398148 creator A5066971314 @default.
• W3202398148 creator A5071626950 @default.
• W3202398148 creator A5076016774 @default.
• W3202398148 date "2022-02-01" @default.
• W3202398148 modified "2023-09-27" @default.
• W3202398148 title "Parkinsonism and dystonia: Clinical spectrum and diagnostic clues" @default.
• W3202398148 cites W1410841433 @default.
• W3202398148 cites W1502917522 @default.
• W3202398148 cites W1523431989 @default.
• W3202398148 cites W1553500185 @default.
• W3202398148 cites W1841551267 @default.
• W3202398148 cites W1871463035 @default.
• W3202398148 cites W1905081641 @default.
• W3202398148 cites W1974163301 @default.
• W3202398148 cites W1993178255 @default.
• W3202398148 cites W1999260106 @default.
• W3202398148 cites W2012544459 @default.
• W3202398148 cites W2013082690 @default.
• W3202398148 cites W2016100283 @default.
• W3202398148 cites W2030916925 @default.
• W3202398148 cites W2035418978 @default.
• W3202398148 cites W2037360314 @default.
• W3202398148 cites W2037654143 @default.
• W3202398148 cites W2042030637 @default.
• W3202398148 cites W2045649370 @default.
• W3202398148 cites W2047859554 @default.
• W3202398148 cites W2055063567 @default.
• W3202398148 cites W2057509775 @default.
• W3202398148 cites W2059933815 @default.
• W3202398148 cites W2061621819 @default.
• W3202398148 cites W2069086420 @default.
• W3202398148 cites W2075832622 @default.
• W3202398148 cites W2083278036 @default.
• W3202398148 cites W2095908732 @default.
• W3202398148 cites W2097132970 @default.
• W3202398148 cites W2098586075 @default.
• W3202398148 cites W2104055172 @default.
• W3202398148 cites W2109762591 @default.
• W3202398148 cites W2112455323 @default.
• W3202398148 cites W2121439756 @default.
• W3202398148 cites W2128672884 @default.
• W3202398148 cites W2129682862 @default.
• W3202398148 cites W2131134103 @default.
• W3202398148 cites W2141283639 @default.
• W3202398148 cites W2147078172 @default.
• W3202398148 cites W2147463443 @default.
• W3202398148 cites W2152047920 @default.
• W3202398148 cites W2155513971 @default.
• W3202398148 cites W2159545745 @default.
• W3202398148 cites W2168462034 @default.
• W3202398148 cites W2171869954 @default.
• W3202398148 cites W2179073303 @default.
• W3202398148 cites W2220929072 @default.
• W3202398148 cites W2272704506 @default.
• W3202398148 cites W2301530325 @default.
• W3202398148 cites W2314898675 @default.
• W3202398148 cites W2325391937 @default.
• W3202398148 cites W2340947285 @default.
• W3202398148 cites W2342456218 @default.
• W3202398148 cites W2401922463 @default.
• W3202398148 cites W2493702651 @default.
• W3202398148 cites W2550041342 @default.
• W3202398148 cites W2563066585 @default.
• W3202398148 cites W2565603412 @default.
• W3202398148 cites W2574166780 @default.
• W3202398148 cites W2599329853 @default.
• W3202398148 cites W2607570104 @default.
• W3202398148 cites W2619861344 @default.
• W3202398148 cites W2653807385 @default.
• W3202398148 cites W2724299376 @default.
• W3202398148 cites W2742692065 @default.
• W3202398148 cites W2756731354 @default.
• W3202398148 cites W2767502239 @default.
• W3202398148 cites W2773339045 @default.
• W3202398148 cites W2782980117 @default.
• W3202398148 cites W2783446226 @default.
• W3202398148 cites W2794462623 @default.
• W3202398148 cites W2797194936 @default.
• W3202398148 cites W2811441774 @default.
• W3202398148 cites W2883352070 @default.
• W3202398148 cites W2884179398 @default.
• W3202398148 cites W2884439513 @default.
• W3202398148 cites W2897487653 @default.
• W3202398148 cites W2898290174 @default.
• W3202398148 cites W2899723611 @default.
• W3202398148 cites W2911629436 @default.
• W3202398148 cites W2919721092 @default.
• W3202398148 cites W2932131656 @default.
• W3202398148 cites W2944266808 @default.
• W3202398148 cites W2945185414 @default.
• W3202398148 cites W2946536124 @default.
• W3202398148 cites W2952773981 @default.
• W3202398148 cites W2952801565 @default.
• W3202398148 cites W2962784059 @default.
• W3202398148 cites W2966251345 @default.

• next