Matches in SemOpenAlex for { <https://semopenalex.org/work/W3202521504> ?p ?o ?g. }
- W3202521504 abstract "ABSTRACT Billions of doses of COVID-19 vaccines have been administered globally, dramatically reducing SARS-CoV-2 incidence and severity in some settings. Many studies suggest vaccines provide a high degree of protection against infection and disease, but precise estimates vary and studies differ in design, outcomes measured, dosing regime, location, and circulating virus strains. Here we conduct a systematic review of COVID-19 vaccines through February 2022. We included efficacy data from Phase 3 clinical trials for 15 vaccines undergoing WHO Emergency Use Listing evaluation and real-world effectiveness for 8 vaccines with observational studies meeting inclusion criteria. Vaccine metrics collected include protection against asymptomatic infection, any infection, symptomatic COVID-19, and severe outcomes including hospitalization and death, for partial or complete vaccination, and against variants of concern Alpha, Beta, Gamma, Delta, and Omicron. We additionally review the epidemiological principles behind the design and interpretation of vaccine efficacy and effectiveness studies, including important sources of heterogeneity." @default.
- W3202521504 created "2021-10-11" @default.
- W3202521504 creator A5004877246 @default.
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- W3202521504 creator A5061818682 @default.
- W3202521504 creator A5088439810 @default.
- W3202521504 creator A5090208751 @default.
- W3202521504 date "2021-09-25" @default.
- W3202521504 modified "2023-10-10" @default.
- W3202521504 title "A systematic review of COVID-19 vaccine efficacy and effectiveness against SARS-CoV-2 infection and disease" @default.
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