Matches in SemOpenAlex for { <https://semopenalex.org/work/W3202599995> ?p ?o ?g. }
- W3202599995 abstract "Mounting evidence suggests that probiotics can be used to treat allergic asthma by modulating the gut microbiota, and that the effects of probiotics may be influenced by environmental factors such as diet. We conducted a rat model with allergic asthma (AA) modulated by Lactobacillus paracasei, feeding up with high-fat or high-fiber diets based on collecting data from 85 questionnaires. The systemic proinflammatory cytokines were detected by ELISA and the overall structure of fecal microbiota was analyzed via 16S rRNA gene sequencing. The results showed consumption of a high-fiber diet alleviated the allergic symptoms and airway inflammation, and led to improving the imbalance of T-helper type 1 (Th1)/Th2 cells with increased expression of interferon-γ and decreased expression of interleukin-4. Whereas, the high-fat diet had deteriorating implications and skewed the inflammatory perturbation. Furthermore, abundances of phylum Bacteroidetes, families Muribaculaceae, Tannerellaceae, Prevotellaceae, Enterococcaceae, genera Allobaculum, Parabacteroides, and Enterococcus were enriched in L. paracasei-modulating rats fed with high-fiber diet. Firmicutes and Proteobacteria, families Lachnospiraceae, Ruminococcaceae and Desulfovibrionaceae, genera Blautia, unidentified_Ruminococcaceae, unidentified_Clostridiales and Oscillibacter were in relatively high abundance in the rats administered high-fat diet. Association between changed microbiota and inflammatory cytokines was also conferred. These data indicated that the efficacy of L. paracasei in allergic asthma was influenced by different dietary patterns. Hence, diet is important for probiotic therapy when managing allergic asthma." @default.
- W3202599995 created "2021-10-11" @default.
- W3202599995 creator A5004013328 @default.
- W3202599995 creator A5029727052 @default.
- W3202599995 creator A5032833916 @default.
- W3202599995 creator A5037489594 @default.
- W3202599995 creator A5058868850 @default.
- W3202599995 creator A5075571866 @default.
- W3202599995 date "2021-09-27" @default.
- W3202599995 modified "2023-09-27" @default.
- W3202599995 title "Influence of Diet on the Effect of the Probiotic Lactobacillus paracasei in Rats Suffering From Allergic Asthma" @default.
- W3202599995 cites W1545388095 @default.
- W3202599995 cites W1868032452 @default.
- W3202599995 cites W1929605979 @default.
- W3202599995 cites W1968105193 @default.
- W3202599995 cites W1969526806 @default.
- W3202599995 cites W1979507095 @default.
- W3202599995 cites W1991229004 @default.
- W3202599995 cites W2008121639 @default.
- W3202599995 cites W2008993230 @default.
- W3202599995 cites W2009170813 @default.
- W3202599995 cites W2016073847 @default.
- W3202599995 cites W2018283002 @default.
- W3202599995 cites W2030571305 @default.
- W3202599995 cites W2030618731 @default.
- W3202599995 cites W2030631780 @default.
- W3202599995 cites W2031355202 @default.
- W3202599995 cites W2033239478 @default.
- W3202599995 cites W2036396112 @default.
- W3202599995 cites W2037132377 @default.
- W3202599995 cites W2045603174 @default.
- W3202599995 cites W2048469790 @default.
- W3202599995 cites W2049533856 @default.
- W3202599995 cites W2055865722 @default.
- W3202599995 cites W2059861417 @default.
- W3202599995 cites W2064414039 @default.
- W3202599995 cites W2067806364 @default.
- W3202599995 cites W2071424821 @default.
- W3202599995 cites W2075046040 @default.
- W3202599995 cites W2087292184 @default.
- W3202599995 cites W2088192427 @default.
- W3202599995 cites W2096425196 @default.
- W3202599995 cites W2096436144 @default.
- W3202599995 cites W2108376307 @default.
- W3202599995 cites W2110389012 @default.
- W3202599995 cites W2119592066 @default.
- W3202599995 cites W2123895022 @default.
- W3202599995 cites W2124554761 @default.
- W3202599995 cites W2136902889 @default.
- W3202599995 cites W2146805064 @default.
- W3202599995 cites W2157151925 @default.
- W3202599995 cites W2160864683 @default.
- W3202599995 cites W2161357018 @default.
- W3202599995 cites W2162786126 @default.
- W3202599995 cites W2165067288 @default.
- W3202599995 cites W2166501256 @default.
- W3202599995 cites W2166562121 @default.
- W3202599995 cites W2172521887 @default.
- W3202599995 cites W2178408924 @default.
- W3202599995 cites W2261232513 @default.
- W3202599995 cites W2396034350 @default.
- W3202599995 cites W2417154838 @default.
- W3202599995 cites W2462189178 @default.
- W3202599995 cites W2510891607 @default.
- W3202599995 cites W2519618698 @default.
- W3202599995 cites W2588544546 @default.
- W3202599995 cites W2765783533 @default.
- W3202599995 cites W2766426590 @default.
- W3202599995 cites W2767988939 @default.
- W3202599995 cites W2781872300 @default.
- W3202599995 cites W2804679053 @default.
- W3202599995 cites W2884138484 @default.
- W3202599995 cites W2888212375 @default.
- W3202599995 cites W2891962226 @default.
- W3202599995 cites W2898202241 @default.
- W3202599995 cites W2903050047 @default.
- W3202599995 cites W2924139387 @default.
- W3202599995 cites W2971355818 @default.
- W3202599995 cites W2984554901 @default.
- W3202599995 cites W3110800072 @default.
- W3202599995 cites W769303411 @default.
- W3202599995 cites W2921683714 @default.
- W3202599995 doi "https://doi.org/10.3389/fmicb.2021.737622" @default.
- W3202599995 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/8516095" @default.
- W3202599995 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/34659167" @default.
- W3202599995 hasPublicationYear "2021" @default.
- W3202599995 type Work @default.
- W3202599995 sameAs 3202599995 @default.
- W3202599995 citedByCount "6" @default.
- W3202599995 countsByYear W32025999952022 @default.
- W3202599995 countsByYear W32025999952023 @default.
- W3202599995 crossrefType "journal-article" @default.
- W3202599995 hasAuthorship W3202599995A5004013328 @default.
- W3202599995 hasAuthorship W3202599995A5029727052 @default.
- W3202599995 hasAuthorship W3202599995A5032833916 @default.
- W3202599995 hasAuthorship W3202599995A5037489594 @default.
- W3202599995 hasAuthorship W3202599995A5058868850 @default.
- W3202599995 hasAuthorship W3202599995A5075571866 @default.
- W3202599995 hasBestOaLocation W32025999951 @default.
- W3202599995 hasConcept C100544194 @default.