Matches in SemOpenAlex for { <https://semopenalex.org/work/W3202801840> ?p ?o ?g. }
Showing items 1 to 91 of
91
with 100 items per page.
- W3202801840 endingPage "1678" @default.
- W3202801840 startingPage "1669" @default.
- W3202801840 abstract "Purpose Peritoneal spread of neoplastic diseases is considered a fatal condition with a dismal prognosis. Few therapeutic options were offered to these patients and surgery had only palliative character. However, advances in surgical techniques and new drugs development, have changed the management of this terminal stage disease. Cytoreductive surgery (CRS) followed by hyperthermic intraperitoneal chemotherapy (HIPEC), has been proposed as a promising alternative to palliative surgery and systemic chemotherapy, since 1980s. Many changes through all these years have refined the technique and standardized indications and limits. Methods A retrospective study was performed in our medical records, of all patients treated with CRS and HIPEC since 2006. Survival, complications and prognostic factors were studied in a total of 632 patients. Results Female patients were 419 and males were 213. Mean age was 52.6 years. Peritoneal metastases secondary to colorectal cancer were the most frequent treated disease (87 patients), whereas hepatobilliary-pancreatic neoplastic diseases and sarcomas were the less frequent causes of peritoneal carcinomatosis. Patients with peritoneal metastases from ovarian cancer, treated with systemic chemotherapy and then received interval cytoreductive surgery with HIPEC, were the largest group that are still alive (43%), while only 35% of patients with hepatobilliary-pancreatic cancer and peritoneal disease are alive at present. Gender, age, peritoneal cancer index (PCI), completeness of cytoreduction score (CCs), and number of complications were important prognostic factors of overall survival. Conclusions Peritoneal carcinomatosis is still considered a final stage disease with a poor prognosis. The confinement of the neoplastic disease in the peritoneal cavity has led to the development of local therapies with promising results. CRS and HIPEC have evolved significantly over the past several years and are at the present the most valuable treatment in highly selected patients with peritoneal carcinomatosis." @default.
- W3202801840 created "2021-10-11" @default.
- W3202801840 creator A5001912493 @default.
- W3202801840 creator A5036465749 @default.
- W3202801840 creator A5042968455 @default.
- W3202801840 creator A5052400715 @default.
- W3202801840 creator A5061732659 @default.
- W3202801840 creator A5062385942 @default.
- W3202801840 creator A5081619402 @default.
- W3202801840 date "2021-07-01" @default.
- W3202801840 modified "2023-09-24" @default.
- W3202801840 title "Cytoreductive surgery and HIPEC for peritoneal metastasis. Justified hope or desperate illusion? Fifteen years of experience from a Greek Peritoneal Surface Malignancy center." @default.
- W3202801840 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/34565035" @default.
- W3202801840 hasPublicationYear "2021" @default.
- W3202801840 type Work @default.
- W3202801840 sameAs 3202801840 @default.
- W3202801840 citedByCount "1" @default.
- W3202801840 countsByYear W32028018402022 @default.
- W3202801840 crossrefType "journal-article" @default.
- W3202801840 hasAuthorship W3202801840A5001912493 @default.
- W3202801840 hasAuthorship W3202801840A5036465749 @default.
- W3202801840 hasAuthorship W3202801840A5042968455 @default.
- W3202801840 hasAuthorship W3202801840A5052400715 @default.
- W3202801840 hasAuthorship W3202801840A5061732659 @default.
- W3202801840 hasAuthorship W3202801840A5062385942 @default.
- W3202801840 hasAuthorship W3202801840A5081619402 @default.
- W3202801840 hasConcept C121608353 @default.
- W3202801840 hasConcept C126322002 @default.
- W3202801840 hasConcept C141071460 @default.
- W3202801840 hasConcept C142724271 @default.
- W3202801840 hasConcept C143998085 @default.
- W3202801840 hasConcept C146357865 @default.
- W3202801840 hasConcept C151730666 @default.
- W3202801840 hasConcept C2776694085 @default.
- W3202801840 hasConcept C2777407522 @default.
- W3202801840 hasConcept C2778536324 @default.
- W3202801840 hasConcept C2778995398 @default.
- W3202801840 hasConcept C2779458272 @default.
- W3202801840 hasConcept C2780140570 @default.
- W3202801840 hasConcept C2780427987 @default.
- W3202801840 hasConcept C2994223192 @default.
- W3202801840 hasConcept C71924100 @default.
- W3202801840 hasConcept C86803240 @default.
- W3202801840 hasConceptScore W3202801840C121608353 @default.
- W3202801840 hasConceptScore W3202801840C126322002 @default.
- W3202801840 hasConceptScore W3202801840C141071460 @default.
- W3202801840 hasConceptScore W3202801840C142724271 @default.
- W3202801840 hasConceptScore W3202801840C143998085 @default.
- W3202801840 hasConceptScore W3202801840C146357865 @default.
- W3202801840 hasConceptScore W3202801840C151730666 @default.
- W3202801840 hasConceptScore W3202801840C2776694085 @default.
- W3202801840 hasConceptScore W3202801840C2777407522 @default.
- W3202801840 hasConceptScore W3202801840C2778536324 @default.
- W3202801840 hasConceptScore W3202801840C2778995398 @default.
- W3202801840 hasConceptScore W3202801840C2779458272 @default.
- W3202801840 hasConceptScore W3202801840C2780140570 @default.
- W3202801840 hasConceptScore W3202801840C2780427987 @default.
- W3202801840 hasConceptScore W3202801840C2994223192 @default.
- W3202801840 hasConceptScore W3202801840C71924100 @default.
- W3202801840 hasConceptScore W3202801840C86803240 @default.
- W3202801840 hasIssue "4" @default.
- W3202801840 hasLocation W32028018401 @default.
- W3202801840 hasOpenAccess W3202801840 @default.
- W3202801840 hasPrimaryLocation W32028018401 @default.
- W3202801840 hasRelatedWork W1964160152 @default.
- W3202801840 hasRelatedWork W1994674684 @default.
- W3202801840 hasRelatedWork W1994986502 @default.
- W3202801840 hasRelatedWork W2009536508 @default.
- W3202801840 hasRelatedWork W2018195451 @default.
- W3202801840 hasRelatedWork W2044035410 @default.
- W3202801840 hasRelatedWork W2044768082 @default.
- W3202801840 hasRelatedWork W205856757 @default.
- W3202801840 hasRelatedWork W2072502458 @default.
- W3202801840 hasRelatedWork W2096919405 @default.
- W3202801840 hasRelatedWork W2165798026 @default.
- W3202801840 hasRelatedWork W2169103803 @default.
- W3202801840 hasRelatedWork W2190648943 @default.
- W3202801840 hasRelatedWork W2252447036 @default.
- W3202801840 hasRelatedWork W2399929396 @default.
- W3202801840 hasRelatedWork W2401038464 @default.
- W3202801840 hasRelatedWork W2531711103 @default.
- W3202801840 hasRelatedWork W2772421854 @default.
- W3202801840 hasRelatedWork W2793185394 @default.
- W3202801840 hasRelatedWork W2944493991 @default.
- W3202801840 hasVolume "26" @default.
- W3202801840 isParatext "false" @default.
- W3202801840 isRetracted "false" @default.
- W3202801840 magId "3202801840" @default.
- W3202801840 workType "article" @default.