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- W3202805110 abstract "Despite significant achievements in oncopediatrics there is an increasing amount of children with remote consequences of anticancer treatment. Nutritional disorders are one of the key consequences, the main factors of which are taste disorders. Despite the interest in this issue, an increase in the number of studies, the exact genesis and causal relationships of these violations have not yet been established. Objective. To study the characteristics of taste perception in children with hemoblastosis and CNS tumors after treatment. Material and methods. The authors carried out a cross-sectional study, which included 110 children with hematological malignancies (42 patients) and CNS tumors (68 patients) aged from 10 to 17 years. The after – treatment period was 2–5 years. They analyzed the nutritional screening data (body mass index and survey data). A test for the identification of four tastes (sour, bitter, salty, sweet) was carried out with the solutions in a regulated concentration according to the standard GOST ISO 3972-2014. Results. The majority of children had violations of taste: to bitter taste – 64,6%, sweet – 40%, sour – 43,7%, salty – 33,6%. Children with hemoblastosis had more disorders.Parageusia was more common in children with CNS tumors. Obese children have a greater proportion of these disorders compared to children with malnutrition and normal nutritional status. There is no relationship with the frequency of food intake, its regularity andappetite. Conclusion. The authors have confirmed the presence of nutritional disorders and problems with taste perception that persist for a long time after the end of treatment. Apparently, a significant part of them has a peripheral genesis." @default.
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- W3202805110 date "2021-09-29" @default.
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- W3202805110 title "Taste disorders in children with hemoblastosis and malignant CNS tumors after treatment" @default.
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- W3202805110 doi "https://doi.org/10.21508/1027-4065-2021-66-4-74-80" @default.
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