FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W3202843264> ?p ?o ?g. }

• W3202843264 endingPage "160" @default.
• W3202843264 startingPage "144" @default.
• W3202843264 abstract "Abstract Synthesis of a number of highly oxygenated furo[3,2‐c]pyran/chromen‐4‐one has been accomplished by one‐pot reaction from easily available dehydroacetic acid/3‐acetyl‐4‐hydroxycoumarin or their chalcones and α‐bromoketones. All the synthesized molecules were characterized utilizing various spectroscopic techniques and screened for anticancer activity (in vitro) against three colon (HCT‐116, SW‐620, HT‐24), lung (A‐549), prostate‐(PC‐3), breast (MCF‐7) cell lines. Compounds 5a , 9d , 9f showed good activity against breast MCF‐7 cancer cell line having IC 50 values 6.9, 2.8, 5.3 μM, respectively. Of these compounds, 9d showed better activity against prostate PC‐3 cell line with IC 50 value 3.8 μM. The synthesized compounds were also studied for antibacterial activity (in vitro) using different strains of bacteria ( Bacillus subtilis and Staphylococcus aureus – Gram‐positive and Escherichia coli, Pseudomonas aeruginosa – Gram negative) as well as fungal strains ( Aspergillus niger and Candida albicans ) using Norfloxacin and Fluconazole as antibacterial and antifungal standard drugs, respectively. The antimicrobial screening study showed that compound 9f exhibited promising activity against S. aureus and B. subtilis, while 5h showed excellent and 5i and 9b showed better activity against E. coli . Compounds 5d and 5e showed promising activity against P. aeruginosa . The compounds 5c – 5e displayed excellent activity against C. albicans and A. niger than Fluconazole." @default.
• W3202843264 created "2021-10-11" @default.
• W3202843264 creator A5014316174 @default.
• W3202843264 creator A5032045887 @default.
• W3202843264 creator A5043122923 @default.
• W3202843264 creator A5055440487 @default.
• W3202843264 creator A5062932958 @default.
• W3202843264 creator A5073052786 @default.
• W3202843264 creator A5073771747 @default.
• W3202843264 date "2021-10-08" @default.
• W3202843264 modified "2023-10-16" @default.
• W3202843264 title "Design and synthesis of highly oxygenated furo[3,2‐c]pyran‐4‐ones and furo[3,2‐c]chromen‐4‐ones scaffold as anticancer and antimicrobial agents" @default.
• W3202843264 cites W1139582027 @default.
• W3202843264 cites W1948791258 @default.
• W3202843264 cites W1964053173 @default.
• W3202843264 cites W1968913330 @default.
• W3202843264 cites W1977217146 @default.
• W3202843264 cites W1983223938 @default.
• W3202843264 cites W1984495092 @default.
• W3202843264 cites W2004871071 @default.
• W3202843264 cites W2011484189 @default.
• W3202843264 cites W2020829029 @default.
• W3202843264 cites W2026060080 @default.
• W3202843264 cites W2042663057 @default.
• W3202843264 cites W2047428834 @default.
• W3202843264 cites W2049601585 @default.
• W3202843264 cites W2053569160 @default.
• W3202843264 cites W2062336260 @default.
• W3202843264 cites W2066925684 @default.
• W3202843264 cites W2077023179 @default.
• W3202843264 cites W2083868967 @default.
• W3202843264 cites W2090221498 @default.
• W3202843264 cites W2127783606 @default.
• W3202843264 cites W2150844813 @default.
• W3202843264 cites W2160898259 @default.
• W3202843264 cites W2178377979 @default.
• W3202843264 cites W2204349601 @default.
• W3202843264 cites W2519398740 @default.
• W3202843264 cites W2756167329 @default.
• W3202843264 cites W2783927504 @default.
• W3202843264 cites W2914012784 @default.
• W3202843264 cites W2950070950 @default.
• W3202843264 cites W2951719563 @default.
• W3202843264 cites W2953303466 @default.
• W3202843264 cites W3008032111 @default.
• W3202843264 cites W3109541978 @default.
• W3202843264 doi "https://doi.org/10.1002/jhet.4374" @default.
• W3202843264 hasPublicationYear "2021" @default.
• W3202843264 type Work @default.
• W3202843264 sameAs 3202843264 @default.
• W3202843264 citedByCount "2" @default.
• W3202843264 countsByYear W32028432642022 @default.
• W3202843264 countsByYear W32028432642023 @default.
• W3202843264 crossrefType "journal-article" @default.
• W3202843264 hasAuthorship W3202843264A5014316174 @default.
• W3202843264 hasAuthorship W3202843264A5032045887 @default.
• W3202843264 hasAuthorship W3202843264A5043122923 @default.
• W3202843264 hasAuthorship W3202843264A5055440487 @default.
• W3202843264 hasAuthorship W3202843264A5062932958 @default.
• W3202843264 hasAuthorship W3202843264A5073052786 @default.
• W3202843264 hasAuthorship W3202843264A5073771747 @default.
• W3202843264 hasConcept C104317684 @default.
• W3202843264 hasConcept C178790620 @default.
• W3202843264 hasConcept C185592680 @default.
• W3202843264 hasConcept C2775960407 @default.
• W3202843264 hasConcept C2777272437 @default.
• W3202843264 hasConcept C2777637488 @default.
• W3202843264 hasConcept C2778512257 @default.
• W3202843264 hasConcept C2778746504 @default.
• W3202843264 hasConcept C2779489039 @default.
• W3202843264 hasConcept C2779548794 @default.
• W3202843264 hasConcept C2780104969 @default.
• W3202843264 hasConcept C2780651595 @default.
• W3202843264 hasConcept C2780917455 @default.
• W3202843264 hasConcept C4937899 @default.
• W3202843264 hasConcept C501593827 @default.
• W3202843264 hasConcept C523546767 @default.
• W3202843264 hasConcept C54355233 @default.
• W3202843264 hasConcept C547475151 @default.
• W3202843264 hasConcept C55493867 @default.
• W3202843264 hasConcept C86803240 @default.
• W3202843264 hasConcept C89423630 @default.
• W3202843264 hasConceptScore W3202843264C104317684 @default.
• W3202843264 hasConceptScore W3202843264C178790620 @default.
• W3202843264 hasConceptScore W3202843264C185592680 @default.
• W3202843264 hasConceptScore W3202843264C2775960407 @default.
• W3202843264 hasConceptScore W3202843264C2777272437 @default.
• W3202843264 hasConceptScore W3202843264C2777637488 @default.
• W3202843264 hasConceptScore W3202843264C2778512257 @default.
• W3202843264 hasConceptScore W3202843264C2778746504 @default.
• W3202843264 hasConceptScore W3202843264C2779489039 @default.
• W3202843264 hasConceptScore W3202843264C2779548794 @default.
• W3202843264 hasConceptScore W3202843264C2780104969 @default.
• W3202843264 hasConceptScore W3202843264C2780651595 @default.
• W3202843264 hasConceptScore W3202843264C2780917455 @default.
• W3202843264 hasConceptScore W3202843264C4937899 @default.
• W3202843264 hasConceptScore W3202843264C501593827 @default.
• W3202843264 hasConceptScore W3202843264C523546767 @default.

• next