FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W3202851423> ?p ?o ?g. }

• W3202851423 endingPage "1495" @default.
• W3202851423 startingPage "1495" @default.
• W3202851423 abstract "Mastitis is one of the most frequently encountered diseases in dairy cattle, negatively affecting animal welfare and milk production. For this reason, contributions to understanding its genomic architecture are of great interest. Genome-wide association studies (GWAS) have identified multiple loci associated with somatic cell score (SCS) and mastitis in cattle. However, most of the studies have been conducted in different parts of the world on various breeds, and none of the investigations have studied the genetic architecture of mastitis in Romanian dairy cattle breeds up to this point in time. In this study, we report the first GWAS for SCS in dairy cattle breeds from Romania. For GWAS, we used an Axiom Bovine v3 SNP-chip (>63,000 Single Nucleotide Polymorphism -SNPs) and 33,330 records from 690 cows belonging to Romanian Spotted (RS) and Romanian Brown (RB) cattle. The results found one SNP significantly associated with SCS in the RS breed and 40 suggestive SNPs with -log10 (p) from 4 to 4.9 for RS and from 4 to 5.4 in RB. From these, 14 markers were located near 12 known genes (AKAP8, CLHC1, MEGF10, SATB2, GATA6, SPATA6, COL12A1, EPS8, LUZP2, RAMAC, IL12A and ANKRD55) in RB cattle, 3 markers were close to ZDHHC19, DAPK1 and MMP7 genes, while one SNP overlapped the HERC3 gene in RS cattle. Four genes (HERC3, LUZP2, AKAP8 and MEGF10) associated with SCS in this study were previously reported in different studies. The most significant SNP (rs110749552) associated with SCS was located within the HERC3 gene. In both breeds, the SNPs and position of association signals were distinct among the three parities, denoting that mastitis is controlled by different genes that are dependent according to parity. The current results contribute to an expansion in the body of knowledge regarding the proportion of genetic variability explained by SNPs for SCS in dairy cattle." @default.
• W3202851423 created "2021-10-11" @default.
• W3202851423 creator A5004631425 @default.
• W3202851423 creator A5014631065 @default.
• W3202851423 creator A5033447732 @default.
• W3202851423 creator A5057608588 @default.
• W3202851423 creator A5065264464 @default.
• W3202851423 creator A5076335669 @default.
• W3202851423 creator A5078976173 @default.
• W3202851423 creator A5081202778 @default.
• W3202851423 creator A5089386744 @default.
• W3202851423 date "2021-09-24" @default.
• W3202851423 modified "2023-10-18" @default.
• W3202851423 title "Genome-Wide Association Studies for Milk Somatic Cell Score in Romanian Dairy Cattle" @default.
• W3202851423 cites W1912532809 @default.
• W3202851423 cites W1913178071 @default.
• W3202851423 cites W1981444328 @default.
• W3202851423 cites W1992557168 @default.
• W3202851423 cites W1999312087 @default.
• W3202851423 cites W2018453464 @default.
• W3202851423 cites W2019034479 @default.
• W3202851423 cites W2022489836 @default.
• W3202851423 cites W2024725971 @default.
• W3202851423 cites W2034226738 @default.
• W3202851423 cites W2048979501 @default.
• W3202851423 cites W2051468459 @default.
• W3202851423 cites W2061363731 @default.
• W3202851423 cites W2064013109 @default.
• W3202851423 cites W2083200763 @default.
• W3202851423 cites W2089249029 @default.
• W3202851423 cites W2092494503 @default.
• W3202851423 cites W2099751340 @default.
• W3202851423 cites W2104146295 @default.
• W3202851423 cites W2105616321 @default.
• W3202851423 cites W2108197147 @default.
• W3202851423 cites W2108374802 @default.
• W3202851423 cites W2110974472 @default.
• W3202851423 cites W2127220612 @default.
• W3202851423 cites W2130835122 @default.
• W3202851423 cites W2131478115 @default.
• W3202851423 cites W2136939537 @default.
• W3202851423 cites W2139772586 @default.
• W3202851423 cites W2142637173 @default.
• W3202851423 cites W2144623803 @default.
• W3202851423 cites W2149824640 @default.
• W3202851423 cites W2161633633 @default.
• W3202851423 cites W2199959951 @default.
• W3202851423 cites W2288642394 @default.
• W3202851423 cites W2291309687 @default.
• W3202851423 cites W2339921621 @default.
• W3202851423 cites W2400422056 @default.
• W3202851423 cites W2415114654 @default.
• W3202851423 cites W2754634689 @default.
• W3202851423 cites W2794134966 @default.
• W3202851423 cites W2801104030 @default.
• W3202851423 cites W2802515507 @default.
• W3202851423 cites W2893053176 @default.
• W3202851423 cites W2936556724 @default.
• W3202851423 cites W2953487578 @default.
• W3202851423 cites W2966555412 @default.
• W3202851423 cites W2981909786 @default.
• W3202851423 cites W2982869507 @default.
• W3202851423 cites W3004669275 @default.
• W3202851423 cites W3011271772 @default.
• W3202851423 cites W3023618341 @default.
• W3202851423 cites W3029958796 @default.
• W3202851423 cites W3044867566 @default.
• W3202851423 cites W3118368712 @default.
• W3202851423 cites W3163177653 @default.
• W3202851423 cites W3185926863 @default.
• W3202851423 doi "https://doi.org/10.3390/genes12101495" @default.
• W3202851423 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/8535694" @default.
• W3202851423 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/34680890" @default.
• W3202851423 hasPublicationYear "2021" @default.
• W3202851423 type Work @default.
• W3202851423 sameAs 3202851423 @default.
• W3202851423 citedByCount "7" @default.
• W3202851423 countsByYear W32028514232022 @default.
• W3202851423 countsByYear W32028514232023 @default.
• W3202851423 crossrefType "journal-article" @default.
• W3202851423 hasAuthorship W3202851423A5004631425 @default.
• W3202851423 hasAuthorship W3202851423A5014631065 @default.
• W3202851423 hasAuthorship W3202851423A5033447732 @default.
• W3202851423 hasAuthorship W3202851423A5057608588 @default.
• W3202851423 hasAuthorship W3202851423A5065264464 @default.
• W3202851423 hasAuthorship W3202851423A5076335669 @default.
• W3202851423 hasAuthorship W3202851423A5078976173 @default.
• W3202851423 hasAuthorship W3202851423A5081202778 @default.
• W3202851423 hasAuthorship W3202851423A5089386744 @default.
• W3202851423 hasBestOaLocation W32028514231 @default.
• W3202851423 hasConcept C104317684 @default.
• W3202851423 hasConcept C106208931 @default.
• W3202851423 hasConcept C135763542 @default.
• W3202851423 hasConcept C139275648 @default.
• W3202851423 hasConcept C153209595 @default.
• W3202851423 hasConcept C186413461 @default.
• W3202851423 hasConcept C22641795 @default.
• W3202851423 hasConcept C2776344049 @default.

• next