Matches in SemOpenAlex for { <https://semopenalex.org/work/W3202901824> ?p ?o ?g. }
- W3202901824 abstract "Abstract Immunotherapies such as immune checkpoint blockade (ICB) and adoptive cell therapy (ACT) have revolutionized cancer treatment, especially in patients whose disease was otherwise considered incurable. However, primary and secondary resistance to single agent immunotherapy often results in treatment failure, and only a minority of patients experience long-term benefits. This review article will discuss the relationship between cancer immune response and mechanisms of resistance to immunotherapy. It will also provide a comprehensive review on the latest clinical status of combination therapies (e.g., immunotherapy with chemotherapy, radiation therapy and targeted therapy), and discuss combination therapies approved by the US Food and Drug Administration. It will provide an overview of therapies targeting cytokines and other soluble immunoregulatory factors, ACT, virotherapy, innate immune modifiers and cancer vaccines, as well as combination therapies that exploit alternative immune targets and other therapeutic modalities. Finally, this review will include the stimulating insights from the 2020 China Immuno-Oncology Workshop co-organized by the Chinese American Hematologist and Oncologist Network (CAHON), the China National Medical Product Administration (NMPA) and Tsinghua University School of Medicine." @default.
- W3202901824 created "2021-10-11" @default.
- W3202901824 creator A5002360335 @default.
- W3202901824 creator A5002476667 @default.
- W3202901824 creator A5016546967 @default.
- W3202901824 creator A5033510051 @default.
- W3202901824 creator A5052008214 @default.
- W3202901824 creator A5055615075 @default.
- W3202901824 creator A5060335470 @default.
- W3202901824 creator A5079417201 @default.
- W3202901824 date "2021-09-27" @default.
- W3202901824 modified "2023-10-16" @default.
- W3202901824 title "Combination strategies to maximize the benefits of cancer immunotherapy" @default.
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