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- W3202908903 abstract "Uncovering the architecture of white matter axons is fundamental to the study of brain networks. We developed a method for quantifying axonal orientations at a resolution of ~15 micrometers. This method is based on the common Nissl staining technique for postmortem histological slices. Nissl staining reveals the spatial organization of glial cells along axons. Using structure tensor analysis, we leveraged this patterned organization to uncover local axonal orientation. We used Nissl-based structure tensor analysis to extract fine details of axonal architecture and demonstrated its applicability in multiple datasets of humans and nonhuman primates. Nissl-based structure tensor analysis can be used to compare fine-grained features of axonal architecture across species and is widely applicable to existing datasets." @default.
- W3202908903 created "2021-10-11" @default.
- W3202908903 creator A5041281882 @default.
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- W3202908903 date "2021-11-05" @default.
- W3202908903 modified "2023-10-16" @default.
- W3202908903 title "The glial framework reveals white matter fiber architecture in human and primate brains" @default.
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- W3202908903 doi "https://doi.org/10.1126/science.abj7960" @default.
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