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- W3203107720 abstract "Multiplex genome-editing (MGE) technologies are recently developed versatile bioengineering tools for modifying two or more specific DNA loci in a genome with high precision. These genome-editing tools have greatly increased the feasibility of introducing desired changes at multiple nucleotide levels into a target genome. In particular, clustered regularly interspaced short palindromic repeats (CRISPR)/CRISPR-associated protein (Cas) [CRISPR/Cas] system-based MGE tools allow the simultaneous generation of direct mutations precisely at multiple loci in a gene or multiple genes. MGE is enhancing the field of plant molecular biology and providing capabilities for revolutionizing modern crop-breeding methods as it was virtually impossible to edit genomes so precisely at the single base-pair level with prior genome-editing tools, such as zinc-finger nucleases (ZFNs) and transcription activator-like effector nucleases (TALENs). Recently, researchers have not only started using MGE tools to advance genome-editing applications in certain plant science fields but also have attempted to decipher and answer basic questions related to plant biology. In this review, we discuss the current progress that has been made toward the development and utilization of MGE tools with an emphasis on the improvements in plant biology after the discovery of CRISPR/Cas9. Furthermore, the most recent advancements involving CRISPR/Cas applications for editing multiple loci or genes are described. Finally, insights into the strengths and importance of MGE technology in advancing crop-improvement programs are presented." @default.
- W3203107720 created "2021-10-11" @default.
- W3203107720 creator A5001895846 @default.
- W3203107720 creator A5011517981 @default.
- W3203107720 creator A5028222530 @default.
- W3203107720 creator A5065555799 @default.
- W3203107720 date "2021-10-06" @default.
- W3203107720 modified "2023-10-16" @default.
- W3203107720 title "Multiplex Genome-Editing Technologies for Revolutionizing Plant Biology and Crop Improvement" @default.
- W3203107720 cites W1435110089 @default.
- W3203107720 cites W1731173485 @default.
- W3203107720 cites W1906155566 @default.
- W3203107720 cites W1916545949 @default.
- W3203107720 cites W1963554509 @default.
- W3203107720 cites W1972933969 @default.
- W3203107720 cites W1977335029 @default.
- W3203107720 cites W1980201684 @default.
- W3203107720 cites W1982802227 @default.
- W3203107720 cites W1983278548 @default.
- W3203107720 cites W1989568784 @default.
- W3203107720 cites W1992783297 @default.
- W3203107720 cites W2003240933 @default.
- W3203107720 cites W2021767455 @default.
- W3203107720 cites W2026520402 @default.
- W3203107720 cites W2028592324 @default.
- W3203107720 cites W2036176224 @default.
- W3203107720 cites W2038264207 @default.
- W3203107720 cites W2039316426 @default.
- W3203107720 cites W2045435533 @default.
- W3203107720 cites W2055652041 @default.
- W3203107720 cites W2058171894 @default.
- W3203107720 cites W2064815984 @default.
- W3203107720 cites W2074060256 @default.
- W3203107720 cites W2081261052 @default.
- W3203107720 cites W2091140839 @default.
- W3203107720 cites W2097433103 @default.
- W3203107720 cites W2101749257 @default.
- W3203107720 cites W2104459589 @default.
- W3203107720 cites W2111491970 @default.
- W3203107720 cites W2112006537 @default.
- W3203107720 cites W2120775449 @default.
- W3203107720 cites W2122890292 @default.
- W3203107720 cites W2123205135 @default.
- W3203107720 cites W2123746851 @default.
- W3203107720 cites W2125937610 @default.
- W3203107720 cites W2144589618 @default.
- W3203107720 cites W2147114967 @default.
- W3203107720 cites W2152599358 @default.
- W3203107720 cites W2154219213 @default.
- W3203107720 cites W2156319424 @default.
- W3203107720 cites W2157114569 @default.
- W3203107720 cites W2165016943 @default.
- W3203107720 cites W2165869860 @default.
- W3203107720 cites W2176976665 @default.
- W3203107720 cites W2191974075 @default.
- W3203107720 cites W2196121581 @default.
- W3203107720 cites W2210852389 @default.
- W3203107720 cites W2271754458 @default.
- W3203107720 cites W2287477038 @default.
- W3203107720 cites W2336828812 @default.
- W3203107720 cites W2341405505 @default.
- W3203107720 cites W2398256531 @default.
- W3203107720 cites W2416323981 @default.
- W3203107720 cites W2469102908 @default.
- W3203107720 cites W2479783674 @default.
- W3203107720 cites W2509994829 @default.
- W3203107720 cites W2515143162 @default.
- W3203107720 cites W2528613931 @default.
- W3203107720 cites W2537749041 @default.
- W3203107720 cites W2555786730 @default.
- W3203107720 cites W2560230043 @default.
- W3203107720 cites W2561147582 @default.
- W3203107720 cites W2567243116 @default.
- W3203107720 cites W2588577496 @default.
- W3203107720 cites W2592572078 @default.
- W3203107720 cites W2598674316 @default.
- W3203107720 cites W2611661371 @default.
- W3203107720 cites W2612076290 @default.
- W3203107720 cites W2616302079 @default.
- W3203107720 cites W2626475163 @default.
- W3203107720 cites W2673137008 @default.
- W3203107720 cites W2727154980 @default.
- W3203107720 cites W2745111034 @default.
- W3203107720 cites W2754227510 @default.
- W3203107720 cites W2756004972 @default.
- W3203107720 cites W2756471683 @default.
- W3203107720 cites W2768119869 @default.
- W3203107720 cites W2770948545 @default.
- W3203107720 cites W2779499461 @default.
- W3203107720 cites W2784712898 @default.
- W3203107720 cites W2792094074 @default.
- W3203107720 cites W2794886114 @default.
- W3203107720 cites W2801363769 @default.
- W3203107720 cites W2802107954 @default.
- W3203107720 cites W2803295557 @default.
- W3203107720 cites W2806398251 @default.
- W3203107720 cites W2806478486 @default.
- W3203107720 cites W2807979852 @default.
- W3203107720 cites W2810682161 @default.
- W3203107720 cites W2810707372 @default.