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• W3203136906 abstract "Timely management of frontotemporal dysfunction associated with amyotrophic lateral sclerosis (ALS) has important prognostic and therapeutic implications. However, there remains a paucity of research on best practise recommendations to guide the development of interventions for cognitive and behavioural symptoms as part of ALS care. Accordingly, a focus on illness perceptions may provide a preliminary framework for managing cognitive and behavioural symptoms. The aim of the present study was to explore the nature of illness perceptions among ALS patients with cognitive and behavioural symptoms. A total of 39 patients were recruited from a specialised ALS clinic. Factor analysis showed three independent and clinically interpretable factors corresponding to “cognitive and emotion related ALS perceptions,” “cognitive- specific ALS perceptions” and “ALS coherence”. Of these factors, greater perceived cognitive and emotional impacts of ALS were associated with an approximate 4-fold increased risk of behavioural changes ( p &lt; 0.05). Greater perceived cognitive and emotional impacts of ALS was also associated with more rapid disease progression ( p &lt; 0.001). As such, timely provision of intervention addressing perceptions about the impact of ALS on functioning as well as associated emotional distress may optimise clinical management of cognitive and behavioural symptoms of ALS." @default.
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• W3203136906 date "2021-09-24" @default.
• W3203136906 modified "2023-10-17" @default.
• W3203136906 title "Illness Cognitions in ALS: New Insights Into Clinical Management of Behavioural Symptoms" @default.
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• W3203136906 doi "https://doi.org/10.3389/fneur.2021.740693" @default.
• W3203136906 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/8498576" @default.
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• W3203136906 hasPublicationYear "2021" @default.
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