FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W3203182658> ?p ?o ?g. }

• W3203182658 endingPage "1077" @default.
• W3203182658 startingPage "1070" @default.
• W3203182658 abstract "Abstract Children with acute lymphoblastic leukemia (ALL) often experience treatment-related neurocognitive deficits and significant pain. Pain may exacerbate these cognitive impairments. This study examined neuropathic pain and neurocognitive outcomes in survivors of childhood ALL treated with contemporary therapy on a clinical trial (NCT00137111). There were 345 survivors (45% female, M = 6.9 years at diagnosis) who completed neurocognitive assessments including measures of sustained attention, learning and memory, and parent ratings of attention during at least one of 4 time points: on-therapy (Induction and Reinduction), end of therapy, and 2 years post-therapy. At-risk performance was defined as a score at least 1SD below the age-adjusted mean. Data on neuropathic pain (events, duration, and severity according NCI Common Toxicity Criteria) and pharmacologic pain management (opioids and gabapentin) were ascertained. Results showed that 135 survivors (39%) experienced neuropathic pain during treatment. Compared with those without pain, survivors with pain had greater memory impairments at end of therapy (California Verbal Learning Test [CVLT]-Total, 24% vs 12%, P = 0.046). Within the pain group, survivors who experienced a greater number of pain events (CVLT-Total = −0.88, P = 0.023) and those who were treated with opioids (versus gabapentin) had poorer learning and memory performance (CVLT-Total = −0.73, P = 0.011; Short Delay = −0.57, P = 0.024; Long Delay = −0.62, P = 0.012; and Learning Slope = −0.45, P = 0.042) across time points. These are considered medium-to-large effects (SD = 0.45-0.88). Neuropathic pain may be a risk factor for learning problems after therapy completion, and treatment for pain with opioids may also adversely affect neurocognitive performance. Therefore, patients who experience pain may require closer monitoring and additional intervention for neurocognitive impairment." @default.
• W3203182658 created "2021-10-11" @default.
• W3203182658 creator A5018363328 @default.
• W3203182658 creator A5023321800 @default.
• W3203182658 creator A5035601480 @default.
• W3203182658 creator A5049391890 @default.
• W3203182658 creator A5050427262 @default.
• W3203182658 creator A5056645586 @default.
• W3203182658 creator A5087384700 @default.
• W3203182658 date "2021-09-25" @default.
• W3203182658 modified "2023-10-12" @default.
• W3203182658 title "Neuropathic pain and neurocognitive functioning in children treated for acute lymphoblastic leukemia" @default.
• W3203182658 cites W1550516490 @default.
• W3203182658 cites W1888049586 @default.
• W3203182658 cites W1905316557 @default.
• W3203182658 cites W1974648504 @default.
• W3203182658 cites W1990014844 @default.
• W3203182658 cites W2001891841 @default.
• W3203182658 cites W2004994611 @default.
• W3203182658 cites W2035605437 @default.
• W3203182658 cites W2059999488 @default.
• W3203182658 cites W2069494856 @default.
• W3203182658 cites W2099463496 @default.
• W3203182658 cites W2105402351 @default.
• W3203182658 cites W2115114044 @default.
• W3203182658 cites W2130902516 @default.
• W3203182658 cites W2136671582 @default.
• W3203182658 cites W2143618395 @default.
• W3203182658 cites W2147540914 @default.
• W3203182658 cites W2151370396 @default.
• W3203182658 cites W2152962565 @default.
• W3203182658 cites W2162850494 @default.
• W3203182658 cites W2164859678 @default.
• W3203182658 cites W2272185880 @default.
• W3203182658 cites W2302440761 @default.
• W3203182658 cites W2336669207 @default.
• W3203182658 cites W2520273472 @default.
• W3203182658 cites W2561449775 @default.
• W3203182658 cites W2573868101 @default.
• W3203182658 cites W2592295475 @default.
• W3203182658 cites W2603477765 @default.
• W3203182658 cites W2730131221 @default.
• W3203182658 cites W2739012795 @default.
• W3203182658 cites W2799753965 @default.
• W3203182658 cites W2801687989 @default.
• W3203182658 cites W2803773752 @default.
• W3203182658 cites W2806337542 @default.
• W3203182658 cites W2883562154 @default.
• W3203182658 cites W2891388821 @default.
• W3203182658 cites W2905326338 @default.
• W3203182658 cites W2946971743 @default.
• W3203182658 cites W2982699029 @default.
• W3203182658 cites W2997942904 @default.
• W3203182658 cites W3009260571 @default.
• W3203182658 cites W3114815684 @default.
• W3203182658 cites W3154972591 @default.
• W3203182658 cites W3156184215 @default.
• W3203182658 cites W4211119836 @default.
• W3203182658 doi "https://doi.org/10.1097/j.pain.0000000000002485" @default.
• W3203182658 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/34813516" @default.
• W3203182658 hasPublicationYear "2021" @default.
• W3203182658 type Work @default.
• W3203182658 sameAs 3203182658 @default.
• W3203182658 citedByCount "2" @default.
• W3203182658 countsByYear W32031826582022 @default.
• W3203182658 countsByYear W32031826582023 @default.
• W3203182658 crossrefType "journal-article" @default.
• W3203182658 hasAuthorship W3203182658A5018363328 @default.
• W3203182658 hasAuthorship W3203182658A5023321800 @default.
• W3203182658 hasAuthorship W3203182658A5035601480 @default.
• W3203182658 hasAuthorship W3203182658A5049391890 @default.
• W3203182658 hasAuthorship W3203182658A5050427262 @default.
• W3203182658 hasAuthorship W3203182658A5056645586 @default.
• W3203182658 hasAuthorship W3203182658A5087384700 @default.
• W3203182658 hasBestOaLocation W32031826582 @default.
• W3203182658 hasConcept C118552586 @default.
• W3203182658 hasConcept C142724271 @default.
• W3203182658 hasConcept C169900460 @default.
• W3203182658 hasConcept C172467417 @default.
• W3203182658 hasConcept C204787440 @default.
• W3203182658 hasConcept C2776608144 @default.
• W3203182658 hasConcept C2777107010 @default.
• W3203182658 hasConcept C2994444459 @default.
• W3203182658 hasConcept C42219234 @default.
• W3203182658 hasConcept C71924100 @default.
• W3203182658 hasConcept C8290200 @default.
• W3203182658 hasConceptScore W3203182658C118552586 @default.
• W3203182658 hasConceptScore W3203182658C142724271 @default.
• W3203182658 hasConceptScore W3203182658C169900460 @default.
• W3203182658 hasConceptScore W3203182658C172467417 @default.
• W3203182658 hasConceptScore W3203182658C204787440 @default.
• W3203182658 hasConceptScore W3203182658C2776608144 @default.
• W3203182658 hasConceptScore W3203182658C2777107010 @default.
• W3203182658 hasConceptScore W3203182658C2994444459 @default.
• W3203182658 hasConceptScore W3203182658C42219234 @default.
• W3203182658 hasConceptScore W3203182658C71924100 @default.
• W3203182658 hasConceptScore W3203182658C8290200 @default.
• W3203182658 hasIssue "6" @default.

• next