Matches in SemOpenAlex for { <https://semopenalex.org/work/W3203399889> ?p ?o ?g. }
- W3203399889 endingPage "702" @default.
- W3203399889 startingPage "685" @default.
- W3203399889 abstract "The sympathetic nervous system prepares the body for ‘fight or flight’ responses and maintains homeostasis during daily activities such as exercise, eating a meal or regulation of body temperature. Sympathetic regulation of bodily functions requires the establishment and refinement of anatomically and functionally precise connections between postganglionic sympathetic neurons and peripheral organs distributed widely throughout the body. Mechanistic studies of key events in the formation of postganglionic sympathetic neurons during embryonic and early postnatal life, including axon growth, target innervation, neuron survival, and dendrite growth and synapse formation, have advanced the understanding of how neuronal development is shaped by interactions with peripheral tissues and organs. Recent progress has also been made in identifying how the cellular and molecular diversity of sympathetic neurons is established to meet the functional demands of peripheral organs. In this Review, we summarize current knowledge of signalling pathways underlying the development of the sympathetic nervous system. These findings have implications for unravelling the contribution of sympathetic dysfunction stemming, in part, from developmental perturbations to the pathophysiology of peripheral neuropathies and cardiovascular and metabolic disorders. The sympathetic regulation of bodily functions relies on precise connections between sympathetic neurons and peripheral organs. In this Review, Scott-Solomon and colleagues discuss the mechanisms underlying the development of the sympathetic nervous system and provide insight into disorders regulated by this branch of the nervous system." @default.
- W3203399889 created "2021-10-11" @default.
- W3203399889 creator A5005539758 @default.
- W3203399889 creator A5012924780 @default.
- W3203399889 creator A5037393551 @default.
- W3203399889 date "2021-10-01" @default.
- W3203399889 modified "2023-10-17" @default.
- W3203399889 title "The sympathetic nervous system in development and disease" @default.
- W3203399889 cites W1485241464 @default.
- W3203399889 cites W1489696679 @default.
- W3203399889 cites W1513983649 @default.
- W3203399889 cites W1516264649 @default.
- W3203399889 cites W1532174613 @default.
- W3203399889 cites W1551323416 @default.
- W3203399889 cites W1561080057 @default.
- W3203399889 cites W1563535780 @default.
- W3203399889 cites W1567527943 @default.
- W3203399889 cites W1588482966 @default.
- W3203399889 cites W1592550864 @default.
- W3203399889 cites W1598556592 @default.
- W3203399889 cites W1598713761 @default.
- W3203399889 cites W178602103 @default.
- W3203399889 cites W1898112969 @default.
- W3203399889 cites W1914197820 @default.
- W3203399889 cites W1936725718 @default.
- W3203399889 cites W1951245501 @default.
- W3203399889 cites W1953305349 @default.
- W3203399889 cites W1960355435 @default.
- W3203399889 cites W1964768186 @default.
- W3203399889 cites W1966541949 @default.
- W3203399889 cites W1966722784 @default.
- W3203399889 cites W1966917600 @default.
- W3203399889 cites W1969258789 @default.
- W3203399889 cites W1969449517 @default.
- W3203399889 cites W1969479602 @default.
- W3203399889 cites W1970431562 @default.
- W3203399889 cites W1972841407 @default.
- W3203399889 cites W1973256550 @default.
- W3203399889 cites W1974900220 @default.
- W3203399889 cites W1975011053 @default.
- W3203399889 cites W1978090633 @default.
- W3203399889 cites W1979823644 @default.
- W3203399889 cites W1980338308 @default.
- W3203399889 cites W1981377852 @default.
- W3203399889 cites W1982695140 @default.
- W3203399889 cites W1982999999 @default.
- W3203399889 cites W1983547799 @default.
- W3203399889 cites W1985306270 @default.
- W3203399889 cites W1985328527 @default.
- W3203399889 cites W1987703447 @default.
- W3203399889 cites W1987935829 @default.
- W3203399889 cites W1988004907 @default.
- W3203399889 cites W1991738499 @default.
- W3203399889 cites W1995319214 @default.
- W3203399889 cites W1996334595 @default.
- W3203399889 cites W1997973843 @default.
- W3203399889 cites W1998289610 @default.
- W3203399889 cites W2004124758 @default.
- W3203399889 cites W2004179558 @default.
- W3203399889 cites W2007378129 @default.
- W3203399889 cites W2010592389 @default.
- W3203399889 cites W2011925126 @default.
- W3203399889 cites W2014273803 @default.
- W3203399889 cites W2015077953 @default.
- W3203399889 cites W2015173843 @default.
- W3203399889 cites W2016762056 @default.
- W3203399889 cites W2018288912 @default.
- W3203399889 cites W2019286265 @default.
- W3203399889 cites W2019843044 @default.
- W3203399889 cites W2022350658 @default.
- W3203399889 cites W2022878394 @default.
- W3203399889 cites W2024456690 @default.
- W3203399889 cites W2028489659 @default.
- W3203399889 cites W2029293126 @default.
- W3203399889 cites W2029663217 @default.
- W3203399889 cites W2029730520 @default.
- W3203399889 cites W2030204732 @default.
- W3203399889 cites W2031823143 @default.
- W3203399889 cites W2031863862 @default.
- W3203399889 cites W2032180104 @default.
- W3203399889 cites W2032467002 @default.
- W3203399889 cites W2035394996 @default.
- W3203399889 cites W2035799281 @default.
- W3203399889 cites W2036994402 @default.
- W3203399889 cites W2037367816 @default.
- W3203399889 cites W2037760450 @default.
- W3203399889 cites W2039812926 @default.
- W3203399889 cites W2039908544 @default.
- W3203399889 cites W2040506298 @default.
- W3203399889 cites W2042280051 @default.
- W3203399889 cites W2043273143 @default.
- W3203399889 cites W2043479508 @default.
- W3203399889 cites W2043659972 @default.
- W3203399889 cites W2043957439 @default.
- W3203399889 cites W2043992209 @default.
- W3203399889 cites W2044712342 @default.
- W3203399889 cites W2044721985 @default.
- W3203399889 cites W2045855955 @default.