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• W3203399945 startingPage "2371" @default.
• W3203399945 abstract "The search for new fiber supplements that can claim to be prebiotic is expanding fast, as the role of prebiotics and intestinal microbiota in well-being has been well established. This work explored the prebiotic potential of a novel fiber plus D-Limonene supplement (FLS) in comparison to fructooligosaccharides (FOS) over distal colonic fermentation with the in vitro model MICODE (multi-unit in vitro colon gut model). During fermentation, volatilome characterization and core microbiota quantifications were performed, then correlations among volatiles and microbes were interpreted. The results indicated that FLS generated positive effects on the host gut model, determining: (i) eubiosis; (ii) increased abundance of beneficial bacteria, as Bifidobacteriaceae; (iii) production of beneficial compounds, as n-Decanoic acid; (iv) reduction in detrimental bacteria, as Enterobaceteriaceae; (v) reduction in detrimental compounds, as skatole. The approach that we followed permitted us to describe the prebiotic potential of FLS and its ability to steadily maintain the metabolism of colon microbiota over time. This aspect is two-faced and should be investigated further because if a fast microbial turnover and production of beneficial compounds is a hallmark of a prebiotic, the ability to reduce microbiota changes and to reduce imbalances in the productions of microbial metabolites could be an added value to FLS. In fact, it has been recently demonstrated that these aspects could serve as an adjuvant in metabolic disorders and cognitive decline." @default.
• W3203399945 created "2021-10-11" @default.
• W3203399945 creator A5022499232 @default.
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• W3203399945 creator A5065034571 @default.
• W3203399945 date "2021-10-07" @default.
• W3203399945 modified "2023-10-17" @default.
• W3203399945 title "Multiunit In Vitro Colon Model for the Evaluation of Prebiotic Potential of a Fiber Plus D-Limonene Food Supplement" @default.
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• W3203399945 doi "https://doi.org/10.3390/foods10102371" @default.
• W3203399945 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/8535099" @default.
• W3203399945 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/34681420" @default.
• W3203399945 hasPublicationYear "2021" @default.
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