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- W3203559074 abstract "Lung macrophages play important roles in the maintenance of homeostasis, pathogen clearance and immune regulation. The different types of pulmonary macrophages and their roles in lung diseases have attracted attention in recent years. Alveolar macrophages (AMs), including tissue-resident alveolar macrophages (TR-AMs) and monocyte-derived alveolar macrophages (Mo-AMs), as well as interstitial macrophages (IMs) are the major macrophage populations in the lung and have unique characteristics in both steady-state conditions and disease states. The different characteristics of these three types of macrophages determine the different roles they play in the development of disease. Therefore, it is important to fully understand the similarities and differences among these three types of macrophages for the study of lung diseases. In this review, we will discuss the physiological characteristics and unique functions of these three types of macrophages in acute and chronic lung diseases. We will also discuss possible methods to target macrophages in lung diseases." @default.
- W3203559074 created "2021-10-11" @default.
- W3203559074 creator A5029727052 @default.
- W3203559074 creator A5078760796 @default.
- W3203559074 creator A5084409870 @default.
- W3203559074 creator A5088224328 @default.
- W3203559074 date "2021-09-24" @default.
- W3203559074 modified "2023-10-04" @default.
- W3203559074 title "Diversity of Macrophages in Lung Homeostasis and Diseases" @default.
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