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- W3203628407 abstract "Y RNA is a conserved small non-coding RNA whose functions in aging remain unknown. Here, we sought to determine the role of C. elegans Y RNA homologs, CeY RNA (CeY) and stem-bulge RNAs (sbRNAs), in aging. We found that the levels of CeY and sbRNAs generally increased during aging. We showed that CeY was downregulated by oxidative and thermal stresses, whereas several sbRNAs were upregulated by oxidative stress. We did not observe lifespan phenotypes by mutations in CeY-coding yrn-1. Future research under various genetic and environmental conditions is required to further evaluate the role of Y RNA in C. elegans aging." @default.
- W3203628407 created "2021-10-11" @default.
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- W3203628407 date "2021-01-01" @default.
- W3203628407 modified "2023-09-24" @default.
- W3203628407 title "Age-dependent upregulation of Y RNAs in Caenorhabditis elegans." @default.
- W3203628407 doi "https://doi.org/10.17912/micropub.biology.000452" @default.
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