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• W3203650498 abstract "The design and synthesis of single-molecule amphiphilic and multifunctional phototherapeutic agents are important to cancer diagnosis and therapy. In this work, we developed three amphiphilic diketopyrrolopyrrole derivatives (TPADPP, DTPADPP, and TPADDPP) with different donor-acceptor structures and poly(ethylene glycol) side chains. The corresponding nanoparticles (NPs) were obtained via a self-assembly from three amphiphilic DPP derivatives and used as smart phototherapeutic agents for tumor diagnosis and treatment. The three amphiphilic DPP NPs exhibited near-infrared (NIR) emissions and good biocompatibility. Thus, they could be used as fluorescence (FL) imaging agents for guided therapy. DTPADPP NPs and TPADDPP NPs also displayed excellent photothermal performance and high accumulation in the tumor. Owing to these beneficial features, the DTPADPP NPs and TPADDPP NPs synthesized herein are suitable for NIR FL imaging and effective photothermal therapy against the tumor in vivo." @default.
• W3203650498 created "2021-10-11" @default.
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• W3203650498 date "2021-09-28" @default.
• W3203650498 modified "2023-10-16" @default.
• W3203650498 title "Amphiphilic Diketopyrrolopyrrole Derivatives for Efficient Near-Infrared Fluorescence Imaging and Photothermal Therapy" @default.
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• W3203650498 doi "https://doi.org/10.1021/acsomega.1c03947" @default.
• W3203650498 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/8515603" @default.
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• W3203650498 hasPublicationYear "2021" @default.
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