Matches in SemOpenAlex for { <https://semopenalex.org/work/W3203722883> ?p ?o ?g. }
Showing items 1 to 63 of
63
with 100 items per page.
- W3203722883 endingPage "2966" @default.
- W3203722883 startingPage "2966" @default.
- W3203722883 abstract "Background: Osteoarthritis is a major cause of pain and locomotor disability worldwide. Though various pharmacological, mechanical and surgical interventions are used, there is no known cure for OA. The present study was conducted to evaluate anti-inflammatory activity of Ariflex tablet (conceptualized and developed by Ari Healthcare Pvt. Ltd.) in comparison with diclofenac and aceclofenac tablet in carrageenan induced rat paw edema model.Methods: Wistar rats of either sex weighing 150-180 g were taken and divided into 4 groups with 6 animals in each group i.e. group 1 (control group), group 2 (diclofenac tablet), group 3 (aceclofenac tablet) and group 4 (ariflex tablet). The study drugs were orally administered with feeding needle, 30 minutes prior to carrageenan injection. After 30 min 1% w/v of 0.05 ml carrageenan was injected subcutaneously in the rat paw. The paw was marked with ink at the level of lateral malleolus and immersed in mercury up to lateral malleolus mark. The paw volume was measured plethysmographically after injection at 30 minutes, 1 hour, 2 hour, 3 hour, 4 hour and eventually at 5 hour.Results: All the test formulations possess statistically significant (p<0.05) anti-inflammatory activity as compared to control group. The maximum percentage inhibition for Ariflex tablet was 96.97% at the end of 5 hours. When compared to control group, statistically significant reduction of paw edema was observed. The anti-inflammatory activity of Ariflex tablet from 2 hours onwards is comparable to that of diclofenac tablet and aceclofenac tablet.Conclusions: Ariflex tablet possesses significant anti-inflammatory activity." @default.
- W3203722883 created "2021-10-11" @default.
- W3203722883 creator A5044095032 @default.
- W3203722883 creator A5045698609 @default.
- W3203722883 date "2021-09-28" @default.
- W3203722883 modified "2023-09-25" @default.
- W3203722883 title "Evaluation of in vivo anti-inflammatory activity of Ariflex tablet in comparison with diclofenac and aceclofenac tablet in carrageenan induced rat paw edema model" @default.
- W3203722883 doi "https://doi.org/10.18203/2320-6012.ijrms20213916" @default.
- W3203722883 hasPublicationYear "2021" @default.
- W3203722883 type Work @default.
- W3203722883 sameAs 3203722883 @default.
- W3203722883 citedByCount "0" @default.
- W3203722883 crossrefType "journal-article" @default.
- W3203722883 hasAuthorship W3203722883A5044095032 @default.
- W3203722883 hasAuthorship W3203722883A5045698609 @default.
- W3203722883 hasBestOaLocation W32037228831 @default.
- W3203722883 hasConcept C141071460 @default.
- W3203722883 hasConcept C150903083 @default.
- W3203722883 hasConcept C185592680 @default.
- W3203722883 hasConcept C207001950 @default.
- W3203722883 hasConcept C2779826273 @default.
- W3203722883 hasConcept C2780886150 @default.
- W3203722883 hasConcept C2780976021 @default.
- W3203722883 hasConcept C2781227287 @default.
- W3203722883 hasConcept C42219234 @default.
- W3203722883 hasConcept C43617362 @default.
- W3203722883 hasConcept C71924100 @default.
- W3203722883 hasConcept C86803240 @default.
- W3203722883 hasConcept C98274493 @default.
- W3203722883 hasConceptScore W3203722883C141071460 @default.
- W3203722883 hasConceptScore W3203722883C150903083 @default.
- W3203722883 hasConceptScore W3203722883C185592680 @default.
- W3203722883 hasConceptScore W3203722883C207001950 @default.
- W3203722883 hasConceptScore W3203722883C2779826273 @default.
- W3203722883 hasConceptScore W3203722883C2780886150 @default.
- W3203722883 hasConceptScore W3203722883C2780976021 @default.
- W3203722883 hasConceptScore W3203722883C2781227287 @default.
- W3203722883 hasConceptScore W3203722883C42219234 @default.
- W3203722883 hasConceptScore W3203722883C43617362 @default.
- W3203722883 hasConceptScore W3203722883C71924100 @default.
- W3203722883 hasConceptScore W3203722883C86803240 @default.
- W3203722883 hasConceptScore W3203722883C98274493 @default.
- W3203722883 hasIssue "10" @default.
- W3203722883 hasLocation W32037228831 @default.
- W3203722883 hasOpenAccess W3203722883 @default.
- W3203722883 hasPrimaryLocation W32037228831 @default.
- W3203722883 hasRelatedWork W2057033003 @default.
- W3203722883 hasRelatedWork W2063535984 @default.
- W3203722883 hasRelatedWork W2092111972 @default.
- W3203722883 hasRelatedWork W2377559637 @default.
- W3203722883 hasRelatedWork W2412996943 @default.
- W3203722883 hasRelatedWork W2416289301 @default.
- W3203722883 hasRelatedWork W2941282402 @default.
- W3203722883 hasRelatedWork W3160654669 @default.
- W3203722883 hasRelatedWork W3174592413 @default.
- W3203722883 hasRelatedWork W4200192277 @default.
- W3203722883 hasVolume "9" @default.
- W3203722883 isParatext "false" @default.
- W3203722883 isRetracted "false" @default.
- W3203722883 magId "3203722883" @default.
- W3203722883 workType "article" @default.