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- W3203736331 abstract "The correlation between T-cell infiltration and EOC survival suggests that EOC may be sensitive to adoptive cell therapy with autologous tumor-infiltrating lymphocytes (TIL). Carboplatin-paclitaxel chemotherapy (CPC) lowers the number of tumor induced immune suppressive myeloid cells, creating a window-of-opportunity for TILs to exert their effective anti-tumor response. IFNα supports TIL. A phase I/II trial (NCT04072263) was initiated to study the feasibility and safety of TIL during CPC +/- IFNα in patients with recurrent platinum sensitive EOC." @default.
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- W3203736331 date "2021-09-01" @default.
- W3203736331 modified "2023-10-14" @default.
- W3203736331 title "729P Adoptive T-cell therapy during chemotherapy with or without peginterferon-α (IFNα) in patients with platinum sensitive recurrent epithelial ovarian cancer (EOC)" @default.
- W3203736331 doi "https://doi.org/10.1016/j.annonc.2021.08.1172" @default.
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