Matches in SemOpenAlex for { <https://semopenalex.org/work/W3203754509> ?p ?o ?g. }
Showing items 1 to 92 of
92
with 100 items per page.
- W3203754509 abstract "Neurodegenerative disorders (NDs) are a class of rapidly rising devastating diseases and the reason behind are might be an improper function of related genes or a mutation in a particular gene or even could be autoimmune also. Parkinsons disease (PD), Multiple sclerosis (MS), Huntingtons disease (HD) are some of the NDs, and still, incurable fully. Apart from the similarities in symptoms, there are common genes that express somehow a differential manner in patients of PDs, MSs, and HDs. A total of 1197 differentially expressed genes (DEGs) are obtained by analyzing the chosen datasets. The protein interactions by STRING online tool and degree sorted hubs obtained through a plug-in in Cytoscape; Cyto-Hubba. Among the sorted hubs KRAS, CREB1, PIK3CA, JAK2 are the ones that are not only common to all the studied datasets of NDs but also in other neurological disorders like Alzheimers. The enriched pathways with biological process, molecular function, cellular component, and KEGG pathway details are obtained and analyzed using Enricher. This paper frames that the obtained hub genes could be potential biomarkers also and a need for further drug design for finding a possible cure." @default.
- W3203754509 created "2021-10-11" @default.
- W3203754509 creator A5031081644 @default.
- W3203754509 creator A5031494640 @default.
- W3203754509 creator A5040822797 @default.
- W3203754509 creator A5083683534 @default.
- W3203754509 date "2021-09-27" @default.
- W3203754509 modified "2023-10-05" @default.
- W3203754509 title "In-silico analysis: common biomarkers of NDs" @default.
- W3203754509 cites W1270834676 @default.
- W3203754509 cites W1797058518 @default.
- W3203754509 cites W1902929441 @default.
- W3203754509 cites W1985213868 @default.
- W3203754509 cites W2013292648 @default.
- W3203754509 cites W2062957986 @default.
- W3203754509 cites W2083661051 @default.
- W3203754509 cites W2104166384 @default.
- W3203754509 cites W2106391842 @default.
- W3203754509 cites W2131515457 @default.
- W3203754509 cites W2146234294 @default.
- W3203754509 cites W2341128841 @default.
- W3203754509 cites W2345356016 @default.
- W3203754509 cites W2718751133 @default.
- W3203754509 cites W2724288088 @default.
- W3203754509 cites W2744119474 @default.
- W3203754509 cites W2765401047 @default.
- W3203754509 cites W2766378262 @default.
- W3203754509 cites W2884854853 @default.
- W3203754509 cites W2911286776 @default.
- W3203754509 cites W3014459671 @default.
- W3203754509 cites W3050298915 @default.
- W3203754509 cites W3093680832 @default.
- W3203754509 cites W3138813354 @default.
- W3203754509 cites W3184116075 @default.
- W3203754509 doi "https://doi.org/10.1101/2021.09.25.461779" @default.
- W3203754509 hasPublicationYear "2021" @default.
- W3203754509 type Work @default.
- W3203754509 sameAs 3203754509 @default.
- W3203754509 citedByCount "0" @default.
- W3203754509 crossrefType "posted-content" @default.
- W3203754509 hasAuthorship W3203754509A5031081644 @default.
- W3203754509 hasAuthorship W3203754509A5031494640 @default.
- W3203754509 hasAuthorship W3203754509A5040822797 @default.
- W3203754509 hasAuthorship W3203754509A5083683534 @default.
- W3203754509 hasBestOaLocation W32037545091 @default.
- W3203754509 hasConcept C104317684 @default.
- W3203754509 hasConcept C14036430 @default.
- W3203754509 hasConcept C142724271 @default.
- W3203754509 hasConcept C150194340 @default.
- W3203754509 hasConcept C152724338 @default.
- W3203754509 hasConcept C162317418 @default.
- W3203754509 hasConcept C2775905019 @default.
- W3203754509 hasConcept C2779134260 @default.
- W3203754509 hasConcept C2781187634 @default.
- W3203754509 hasConcept C501734568 @default.
- W3203754509 hasConcept C54355233 @default.
- W3203754509 hasConcept C60644358 @default.
- W3203754509 hasConcept C70721500 @default.
- W3203754509 hasConcept C71924100 @default.
- W3203754509 hasConcept C86803240 @default.
- W3203754509 hasConceptScore W3203754509C104317684 @default.
- W3203754509 hasConceptScore W3203754509C14036430 @default.
- W3203754509 hasConceptScore W3203754509C142724271 @default.
- W3203754509 hasConceptScore W3203754509C150194340 @default.
- W3203754509 hasConceptScore W3203754509C152724338 @default.
- W3203754509 hasConceptScore W3203754509C162317418 @default.
- W3203754509 hasConceptScore W3203754509C2775905019 @default.
- W3203754509 hasConceptScore W3203754509C2779134260 @default.
- W3203754509 hasConceptScore W3203754509C2781187634 @default.
- W3203754509 hasConceptScore W3203754509C501734568 @default.
- W3203754509 hasConceptScore W3203754509C54355233 @default.
- W3203754509 hasConceptScore W3203754509C60644358 @default.
- W3203754509 hasConceptScore W3203754509C70721500 @default.
- W3203754509 hasConceptScore W3203754509C71924100 @default.
- W3203754509 hasConceptScore W3203754509C86803240 @default.
- W3203754509 hasLocation W32037545091 @default.
- W3203754509 hasOpenAccess W3203754509 @default.
- W3203754509 hasPrimaryLocation W32037545091 @default.
- W3203754509 hasRelatedWork W1528013904 @default.
- W3203754509 hasRelatedWork W2060958215 @default.
- W3203754509 hasRelatedWork W2068588654 @default.
- W3203754509 hasRelatedWork W2119462611 @default.
- W3203754509 hasRelatedWork W2548465033 @default.
- W3203754509 hasRelatedWork W2802217527 @default.
- W3203754509 hasRelatedWork W3081807611 @default.
- W3203754509 hasRelatedWork W3135849929 @default.
- W3203754509 hasRelatedWork W3203754509 @default.
- W3203754509 hasRelatedWork W2466502141 @default.
- W3203754509 isParatext "false" @default.
- W3203754509 isRetracted "false" @default.
- W3203754509 magId "3203754509" @default.
- W3203754509 workType "article" @default.