Matches in SemOpenAlex for { <https://semopenalex.org/work/W3203852078> ?p ?o ?g. }
Showing items 1 to 86 of
86
with 100 items per page.
- W3203852078 endingPage "289" @default.
- W3203852078 startingPage "284" @default.
- W3203852078 abstract "Summary. A number of clinical and population-based studies have shown a link between the development of insulin resistance and type 2 diabetes mellitus and hepatitis C.Purpose of research:to study the frequency of type 2 diabetes mellitus and its course in patients with chronic viral hepatitis C and B during antiviral therapy.Material and methods:213 patients (164 with CVH C, 34 with CVH B and 15 with CVH B + C) were examined before and in the course of treatment. All patients received standard antiviral therapy. In patients with type 2 diabetes, the level of fastingglycemiawas determined daily in the first 8-12 weeks of treatment. The level of glycemia was determined at the laboratory at least once every 2 weeks. Glycated hemoglobin was determined every 3 months during treatment and another 6 months after completion of the antiviral therapy.Results: In the group of patients with CVH C, type 2 diabetes mellitus occurred 2 times more often (13.4%) than in groups with CVH B (6.1%) with a reliability of p <0.01. With HCV genotype 3 is 2.5 times more often than with genotype 1 (p <0.001). Among patients, type 2 diabetes is 2.5 times more often men than women (p <0.01).Upon reaching an early virological response in 77.3% of patients, the level of glycemia returned to normal. The correlation coefficient between the achievement of a full virological response (negative PCR results on HCV RNA) and the normalization of the level of glycemia was 0.75. Glycemia control was maintained for 6 months after the completion of the antiviral therapy in the background of a persistent virological response.Conclusions:The presence of diabetes is the basis for screening for HCV, regardless of other factors. 75-77% of type 2 diabetes mellitus in the cohort of patients with CVH C is possibly virus-associated. Treatment of HCV infection can lead to a cure for type 2 diabetes mellitus in this category of patients." @default.
- W3203852078 created "2021-10-11" @default.
- W3203852078 creator A5006755481 @default.
- W3203852078 creator A5035549330 @default.
- W3203852078 creator A5039650435 @default.
- W3203852078 creator A5041439479 @default.
- W3203852078 creator A5046876636 @default.
- W3203852078 creator A5047168366 @default.
- W3203852078 date "2019-01-01" @default.
- W3203852078 modified "2023-09-27" @default.
- W3203852078 title "TYPE 2 DIABETES MELLITUS IN PATIENTS WITH CHRONIC VIRAL HEPATITIS C AND B" @default.
- W3203852078 doi "https://doi.org/10.5530/srp.2019.2.38" @default.
- W3203852078 hasPublicationYear "2019" @default.
- W3203852078 type Work @default.
- W3203852078 sameAs 3203852078 @default.
- W3203852078 citedByCount "0" @default.
- W3203852078 crossrefType "journal-article" @default.
- W3203852078 hasAuthorship W3203852078A5006755481 @default.
- W3203852078 hasAuthorship W3203852078A5035549330 @default.
- W3203852078 hasAuthorship W3203852078A5039650435 @default.
- W3203852078 hasAuthorship W3203852078A5041439479 @default.
- W3203852078 hasAuthorship W3203852078A5046876636 @default.
- W3203852078 hasAuthorship W3203852078A5047168366 @default.
- W3203852078 hasConcept C126322002 @default.
- W3203852078 hasConcept C134018914 @default.
- W3203852078 hasConcept C203014093 @default.
- W3203852078 hasConcept C2522874641 @default.
- W3203852078 hasConcept C2776455275 @default.
- W3203852078 hasConcept C2777180221 @default.
- W3203852078 hasConcept C2777382497 @default.
- W3203852078 hasConcept C2777538456 @default.
- W3203852078 hasConcept C2908647359 @default.
- W3203852078 hasConcept C2910068830 @default.
- W3203852078 hasConcept C2993512173 @default.
- W3203852078 hasConcept C3020491458 @default.
- W3203852078 hasConcept C555293320 @default.
- W3203852078 hasConcept C71924100 @default.
- W3203852078 hasConcept C90924648 @default.
- W3203852078 hasConcept C99454951 @default.
- W3203852078 hasConceptScore W3203852078C126322002 @default.
- W3203852078 hasConceptScore W3203852078C134018914 @default.
- W3203852078 hasConceptScore W3203852078C203014093 @default.
- W3203852078 hasConceptScore W3203852078C2522874641 @default.
- W3203852078 hasConceptScore W3203852078C2776455275 @default.
- W3203852078 hasConceptScore W3203852078C2777180221 @default.
- W3203852078 hasConceptScore W3203852078C2777382497 @default.
- W3203852078 hasConceptScore W3203852078C2777538456 @default.
- W3203852078 hasConceptScore W3203852078C2908647359 @default.
- W3203852078 hasConceptScore W3203852078C2910068830 @default.
- W3203852078 hasConceptScore W3203852078C2993512173 @default.
- W3203852078 hasConceptScore W3203852078C3020491458 @default.
- W3203852078 hasConceptScore W3203852078C555293320 @default.
- W3203852078 hasConceptScore W3203852078C71924100 @default.
- W3203852078 hasConceptScore W3203852078C90924648 @default.
- W3203852078 hasConceptScore W3203852078C99454951 @default.
- W3203852078 hasIssue "2" @default.
- W3203852078 hasLocation W32038520781 @default.
- W3203852078 hasOpenAccess W3203852078 @default.
- W3203852078 hasPrimaryLocation W32038520781 @default.
- W3203852078 hasRelatedWork W1987012521 @default.
- W3203852078 hasRelatedWork W2019598977 @default.
- W3203852078 hasRelatedWork W2033664904 @default.
- W3203852078 hasRelatedWork W2060669391 @default.
- W3203852078 hasRelatedWork W2127041576 @default.
- W3203852078 hasRelatedWork W2317619802 @default.
- W3203852078 hasRelatedWork W2371261453 @default.
- W3203852078 hasRelatedWork W2731273613 @default.
- W3203852078 hasRelatedWork W2770468868 @default.
- W3203852078 hasRelatedWork W2938704128 @default.
- W3203852078 hasRelatedWork W3000468036 @default.
- W3203852078 hasRelatedWork W3007523148 @default.
- W3203852078 hasRelatedWork W3008424479 @default.
- W3203852078 hasRelatedWork W3013925973 @default.
- W3203852078 hasRelatedWork W3025691253 @default.
- W3203852078 hasRelatedWork W3102828734 @default.
- W3203852078 hasRelatedWork W3158779356 @default.
- W3203852078 hasRelatedWork W3159204123 @default.
- W3203852078 hasRelatedWork W3173099300 @default.
- W3203852078 hasRelatedWork W3211793701 @default.
- W3203852078 hasVolume "10" @default.
- W3203852078 isParatext "false" @default.
- W3203852078 isRetracted "false" @default.
- W3203852078 magId "3203852078" @default.
- W3203852078 workType "article" @default.