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• W3203900512 startingPage "12021" @default.
• W3203900512 abstract "A specialized method for ochratoxin A (OTA) determination on fermented teas was developed and validated using ultraperformance liquid chromatography tandem mass spectrometry (UPLC-MS/MS). Methodology results showed that recovery, relative standard deviation, accuracy, and precision were qualified. The limits of detection and quantification were 0.32 and 0.96 μg/kg, respectively. Two of 158 collected samples were screened for OTA contamination. Comprehensive risk assessment based on OTA contaminations of this study and other peer-reviewed publications was performed. The highest hazard quotient (HQ) value (8.86 × 10-2) and the highest 1/MoE value (8.61 × 10-5) in probabilistic assessment were equally below the recommended non-neoplastic and neoplastic thresholds, indicating no health risks. However, the HQ and 1/MoE values of the 95th percentiles in 20-39 and ≥50 years of age were close to thresholds of 1.0 and 1.0 × 10-4, respectively. Under the extreme case, there were only a few scenarios (e.g., 40-49 years of age) of HQ values below the non-neoplastic threshold, but the 1/MoE value of each group exceeded the neoplastic threshold. This is the first extensive risk assessment on OTA from fermented teas worldwide, but the sample size is still limited, and a large number of samples is encouraged in a future study for a more accurate assessment." @default.
• W3203900512 created "2021-10-11" @default.
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• W3203900512 date "2021-10-04" @default.
• W3203900512 modified "2023-10-17" @default.
• W3203900512 title "Determination and Comprehensive Risk Assessment of Dietary Exposure to Ochratoxin A on Fermented Teas" @default.
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• W3203900512 doi "https://doi.org/10.1021/acs.jafc.1c04824" @default.
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