FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W3203927525> ?p ?o ?g. }

• W3203927525 abstract "Cardiac surgery with cardiopulmonary bypass (CPB) is associated with a systemic inflammatory syndrome that adversely impacts cardiopulmonary function and can contribute to prolonged postoperative recovery. Intra-operative ultrafiltration during CPB is a strategy developed by pediatric cardiac specialists, aiming to dampen the inflammatory syndrome by removing circulating cytokines and improving coagulation profiles during the cardiac operation. Although ultrafiltration is commonly used in the pediatric population, it is not routinely used in the adult population. This study aims to evaluate if randomized evidence supports the use of continuous intra-operative ultrafiltration to enhance recovery for adults undergoing cardiac surgery with CPB.This systematic review and meta-analysis will include randomized controlled trials (RCT) that feature continuous forms of ultrafiltration during adult cardiac surgery with CPB, specifically assessing for benefit in mortality rates, invasive ventilation time and intensive care unit length of stay (ICU LOS). Relevant RCTs will be retrieved from databases, including MEDLINE, Embase, CENTRAL and Scopus, by a pre-defined search strategy. Search results will be screened for inclusion and exclusion criteria by two independent persons with consensus. Selected RCTs will have study demographics and outcome data extracted by two independent persons and transferred into RevMan. Risk of bias will be independently assessed by the Revised Cochrane Risk-of-Bias (RoB2) tool and studies rated as low-, some-, or high- risk of bias. Meta-analyses will compare the intervention of continuous ultrafiltration against comparators in terms of mortality, ventilation time, ICU LOS, and renal failure. Heterogeneity will be measured by the χ2 test and described by the I2 statistic. A sensitivity analysis will be completed by excluding included studies judged to have a high risk of bias. Summary of findings and certainty of the evidence, determined by the GRADE approach, will display the analysis findings.The findings of this systematic review and meta-analysis will summarize the evidence to date of continuous forms of ultrafiltration in adult cardiac surgery with CPB, to both inform adult cardiac specialists about this technique and identify critical questions for future research in this subject area.This systematic review and meta-analysis is registered in PROSPERO CRD42020219309 ( https://www.crd.york.ac.uk/prospero/display_record.php?ID=CRD42020219309 )." @default.
• W3203927525 created "2021-10-11" @default.
• W3203927525 creator A5013965253 @default.
• W3203927525 creator A5019572401 @default.
• W3203927525 creator A5024749734 @default.
• W3203927525 creator A5026239919 @default.
• W3203927525 creator A5045240657 @default.
• W3203927525 creator A5050902327 @default.
• W3203927525 date "2021-10-08" @default.
• W3203927525 modified "2023-10-06" @default.
• W3203927525 title "Do continuous forms of intra-operative ultrafiltration enhance recovery after adult cardiac surgery with cardiopulmonary bypass? A protocol for systematic review and meta-analysis of randomized controlled trials" @default.
• W3203927525 cites W2089758120 @default.
• W3203927525 cites W2099953795 @default.
• W3203927525 cites W2143077267 @default.
• W3203927525 cites W2513181318 @default.
• W3203927525 cites W2567362164 @default.
• W3203927525 cites W2983065936 @default.
• W3203927525 cites W2990505687 @default.
• W3203927525 cites W4294215472 @default.
• W3203927525 doi "https://doi.org/10.1186/s13643-021-01826-y" @default.
• W3203927525 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/8499556" @default.
• W3203927525 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/34625118" @default.
• W3203927525 hasPublicationYear "2021" @default.
• W3203927525 type Work @default.
• W3203927525 sameAs 3203927525 @default.
• W3203927525 citedByCount "1" @default.
• W3203927525 countsByYear W32039275252023 @default.
• W3203927525 crossrefType "journal-article" @default.
• W3203927525 hasAuthorship W3203927525A5013965253 @default.
• W3203927525 hasAuthorship W3203927525A5019572401 @default.
• W3203927525 hasAuthorship W3203927525A5024749734 @default.
• W3203927525 hasAuthorship W3203927525A5026239919 @default.
• W3203927525 hasAuthorship W3203927525A5045240657 @default.
• W3203927525 hasAuthorship W3203927525A5050902327 @default.
• W3203927525 hasBestOaLocation W32039275251 @default.
• W3203927525 hasConcept C126322002 @default.
• W3203927525 hasConcept C168563851 @default.
• W3203927525 hasConcept C17744445 @default.
• W3203927525 hasConcept C177713679 @default.
• W3203927525 hasConcept C199539241 @default.
• W3203927525 hasConcept C2776376669 @default.
• W3203927525 hasConcept C2778063415 @default.
• W3203927525 hasConcept C2778789114 @default.
• W3203927525 hasConcept C2778865887 @default.
• W3203927525 hasConcept C2778881276 @default.
• W3203927525 hasConcept C2779473830 @default.
• W3203927525 hasConcept C2908647359 @default.
• W3203927525 hasConcept C71924100 @default.
• W3203927525 hasConcept C95190672 @default.
• W3203927525 hasConcept C99454951 @default.
• W3203927525 hasConceptScore W3203927525C126322002 @default.
• W3203927525 hasConceptScore W3203927525C168563851 @default.
• W3203927525 hasConceptScore W3203927525C17744445 @default.
• W3203927525 hasConceptScore W3203927525C177713679 @default.
• W3203927525 hasConceptScore W3203927525C199539241 @default.
• W3203927525 hasConceptScore W3203927525C2776376669 @default.
• W3203927525 hasConceptScore W3203927525C2778063415 @default.
• W3203927525 hasConceptScore W3203927525C2778789114 @default.
• W3203927525 hasConceptScore W3203927525C2778865887 @default.
• W3203927525 hasConceptScore W3203927525C2778881276 @default.
• W3203927525 hasConceptScore W3203927525C2779473830 @default.
• W3203927525 hasConceptScore W3203927525C2908647359 @default.
• W3203927525 hasConceptScore W3203927525C71924100 @default.
• W3203927525 hasConceptScore W3203927525C95190672 @default.
• W3203927525 hasConceptScore W3203927525C99454951 @default.
• W3203927525 hasIssue "1" @default.
• W3203927525 hasLocation W32039275251 @default.
• W3203927525 hasLocation W32039275252 @default.
• W3203927525 hasLocation W32039275253 @default.
• W3203927525 hasLocation W32039275254 @default.
• W3203927525 hasOpenAccess W3203927525 @default.
• W3203927525 hasPrimaryLocation W32039275251 @default.
• W3203927525 hasRelatedWork W172659699 @default.
• W3203927525 hasRelatedWork W2045806005 @default.
• W3203927525 hasRelatedWork W2049733093 @default.
• W3203927525 hasRelatedWork W2136632926 @default.
• W3203927525 hasRelatedWork W2415759773 @default.
• W3203927525 hasRelatedWork W3022091582 @default.
• W3203927525 hasRelatedWork W3129089517 @default.
• W3203927525 hasRelatedWork W1528660514 @default.
• W3203927525 hasRelatedWork W2083697902 @default.
• W3203927525 hasRelatedWork W2490008797 @default.
• W3203927525 hasVolume "10" @default.
• W3203927525 isParatext "false" @default.
• W3203927525 isRetracted "false" @default.
• W3203927525 magId "3203927525" @default.
• W3203927525 workType "article" @default.