Matches in SemOpenAlex for { <https://semopenalex.org/work/W3203937047> ?p ?o ?g. }
Showing items 1 to 88 of
88
with 100 items per page.
- W3203937047 endingPage "75" @default.
- W3203937047 startingPage "69" @default.
- W3203937047 abstract "Younger age of onset and mild cognitive impairment (MCI) are both independently associated with poorer quality of life (QOL) in Parkinson's disease (PD).The primary objective was to determine whether MCI differentially impacts QOL in young-onset PD (YOPD) and typical-onset PD (TOPD).YOPD patients (n = 77) were diagnosed at age 50 or younger, TOPD (n = 77) were diagnosed after age 50, and the groups were matched for cognitive status, education, and disease duration. Patients' cognitive status was classified as MCI or cognitively normal (CN) based on MDS Level II criteria. QOL was assessed using the Parkinson's Disease Questionnaire (PDQ-39). ANCOVAs were conducted for each PDQ-39 subscale, with age of onset and cognitive status as between-subjects factors and several covariates included.An interaction for the Cognition domain revealed that in TOPD, PD-MCI patients reported poorer QOL than CN patients, whereas there was no effect of MCI on cognitive satisfaction in YOPD. There was a main effect of age on Emotional Well-Being, as YOPD reported poorer QOL than TOPD in this domain. There were main effects of cognitive status, with PD-MCI patients reporting worse QOL than CN patients in the domains of Social Support, Communication, ADLs, and Mobility.The interaction revealed that PD-MCI has a greater impact on degree of cognitive concerns (cognitive QOL) in TOPD versus YOPD. A more nuanced understanding of the effects of age of onset, MCI, and their interactions on QOL in PD will inform interventions aimed at improving quality of life in this population." @default.
- W3203937047 created "2021-10-11" @default.
- W3203937047 creator A5036755275 @default.
- W3203937047 creator A5052244592 @default.
- W3203937047 creator A5056978596 @default.
- W3203937047 date "2021-10-16" @default.
- W3203937047 modified "2023-10-16" @default.
- W3203937047 title "Impact of mild cognitive impairment on quality of life in young and typical onset Parkinson's disease" @default.
- W3203937047 cites W1570641438 @default.
- W3203937047 cites W2008560062 @default.
- W3203937047 cites W2032662883 @default.
- W3203937047 cites W2052152078 @default.
- W3203937047 cites W2074302943 @default.
- W3203937047 cites W2074981988 @default.
- W3203937047 cites W2077567545 @default.
- W3203937047 cites W2089085990 @default.
- W3203937047 cites W2102535081 @default.
- W3203937047 cites W2112254680 @default.
- W3203937047 cites W2140978740 @default.
- W3203937047 cites W2156013560 @default.
- W3203937047 cites W2325881811 @default.
- W3203937047 cites W2749718288 @default.
- W3203937047 cites W2922558620 @default.
- W3203937047 cites W2948000875 @default.
- W3203937047 cites W3023586323 @default.
- W3203937047 cites W3036652104 @default.
- W3203937047 doi "https://doi.org/10.1002/mdc3.13353" @default.
- W3203937047 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/35005067" @default.
- W3203937047 hasPublicationYear "2021" @default.
- W3203937047 type Work @default.
- W3203937047 sameAs 3203937047 @default.
- W3203937047 citedByCount "2" @default.
- W3203937047 countsByYear W32039370472023 @default.
- W3203937047 crossrefType "journal-article" @default.
- W3203937047 hasAuthorship W3203937047A5036755275 @default.
- W3203937047 hasAuthorship W3203937047A5052244592 @default.
- W3203937047 hasAuthorship W3203937047A5056978596 @default.
- W3203937047 hasBestOaLocation W32039370471 @default.
- W3203937047 hasConcept C118552586 @default.
- W3203937047 hasConcept C126322002 @default.
- W3203937047 hasConcept C15744967 @default.
- W3203937047 hasConcept C169900460 @default.
- W3203937047 hasConcept C27415008 @default.
- W3203937047 hasConcept C2777767895 @default.
- W3203937047 hasConcept C2779134260 @default.
- W3203937047 hasConcept C2779734285 @default.
- W3203937047 hasConcept C2779951463 @default.
- W3203937047 hasConcept C2984915365 @default.
- W3203937047 hasConcept C542102704 @default.
- W3203937047 hasConcept C70410870 @default.
- W3203937047 hasConcept C71924100 @default.
- W3203937047 hasConceptScore W3203937047C118552586 @default.
- W3203937047 hasConceptScore W3203937047C126322002 @default.
- W3203937047 hasConceptScore W3203937047C15744967 @default.
- W3203937047 hasConceptScore W3203937047C169900460 @default.
- W3203937047 hasConceptScore W3203937047C27415008 @default.
- W3203937047 hasConceptScore W3203937047C2777767895 @default.
- W3203937047 hasConceptScore W3203937047C2779134260 @default.
- W3203937047 hasConceptScore W3203937047C2779734285 @default.
- W3203937047 hasConceptScore W3203937047C2779951463 @default.
- W3203937047 hasConceptScore W3203937047C2984915365 @default.
- W3203937047 hasConceptScore W3203937047C542102704 @default.
- W3203937047 hasConceptScore W3203937047C70410870 @default.
- W3203937047 hasConceptScore W3203937047C71924100 @default.
- W3203937047 hasFunder F4320311545 @default.
- W3203937047 hasIssue "1" @default.
- W3203937047 hasLocation W32039370471 @default.
- W3203937047 hasLocation W32039370472 @default.
- W3203937047 hasLocation W32039370473 @default.
- W3203937047 hasOpenAccess W3203937047 @default.
- W3203937047 hasPrimaryLocation W32039370471 @default.
- W3203937047 hasRelatedWork W2206382777 @default.
- W3203937047 hasRelatedWork W2414189039 @default.
- W3203937047 hasRelatedWork W2609134097 @default.
- W3203937047 hasRelatedWork W2748952813 @default.
- W3203937047 hasRelatedWork W2899084033 @default.
- W3203937047 hasRelatedWork W3113538650 @default.
- W3203937047 hasRelatedWork W3134596587 @default.
- W3203937047 hasRelatedWork W3216329096 @default.
- W3203937047 hasRelatedWork W4235719877 @default.
- W3203937047 hasRelatedWork W4380886081 @default.
- W3203937047 hasVolume "9" @default.
- W3203937047 isParatext "false" @default.
- W3203937047 isRetracted "false" @default.
- W3203937047 magId "3203937047" @default.
- W3203937047 workType "article" @default.