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- W3203950744 endingPage "369" @default.
- W3203950744 startingPage "339" @default.
- W3203950744 abstract "Stroke is the second leading cause of death and the leading cause of disability among adults worldwide according to the World Health Organization. Development of efficient strategies for stroke treatment has long been a high priority. Recently remarkable progress has demonstrated that nanotechnology-based methodology shows a great potential to significantly enhance stroke treatment efficiency. This chapter will discuss the general principles for improving thrombolysis efficiency and highlight different strategies and enhancement mechanisms for nanotechnology-based stroke treatment. Two general catalogs will be discussed, passive nanoparticle (NP) treatment and active NP treatment. The compositions, drug-loading mechanisms, NP targeting methods, and drug release strategies of passive NP treatment will be elaborated in detail. For active NP treatment, recent progress on different NP activation mechanisms with or without thrombolytic agent using external magnetic field, ultrasound, or light, are reviewed. The use of active NP drug carriers is the future of nanotechnology-based stroke treatment." @default.
- W3203950744 created "2021-10-11" @default.
- W3203950744 creator A5006897488 @default.
- W3203950744 creator A5061724844 @default.
- W3203950744 creator A5062893409 @default.
- W3203950744 date "2022-01-01" @default.
- W3203950744 modified "2023-09-27" @default.
- W3203950744 title "Nanotechnology for stroke treatment" @default.
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